Abstract: The present invention is directed to the administration of aerosolized particles to specific area of the lungs, and in particular to the targeted delivery of aerosolized pharmaceutical formulations to a specific area of the lungs. More specifically, the present invention relates to devices and methods for depositing aerosolized particles to a specific area of the lungs by regulating aerosolizing parameters of the device. The present invention also relates to devices, systems and methods for disease management, where the aerosolizing parameters are adjusted based on monitoring at least one health parameter.

Abstract: A testing device for detecting vapor emission of at least one leakage point has at least one upstream measuring unit arranged upstream of the leakage point and at least one downstream measuring unit arranged downstream of the leakage point. The at least one upstream and the at least one downstream measuring units are connected serially. The at least one upstream measuring unit determines measured values of a reference stream and the at least one downstream measuring unit determines measured values of the reference stream plus a vapor emission of the leakage point. By comparing the measured values, the humidity quantity and thus the vapor emission at the leakage point can be determined.