Abstract: A method of generating an indication of where, within a geographical region, a mobile unit can move to from a specified origin in the geographical region using a network of navigable elements in the geographical region and in accordance with a total movement budget specified for the mobile unit, the method including: for each sub-region of a set of one or more sub-regions of the geographical region, associating one or more corresponding utilization amounts with said sub-region; identifying an initial navigable element that corresponds to the origin; performing a sequence of steps, wherein each step includes: using an identification function to try to identify an additional navigable element, wherein the additional navigable element is a neighbour of an already-identified navigable element and can be reached by the mobile unit from the origin in accordance with the total movement budget; and in response to the identification function identifying an additional navigable element of at least one sub-region, perfo

Abstract: A method for collision avoidance between a vulnerable road user transportation vehicle and a surrounding transportation vehicle. The user of the vulnerable road user transportation vehicle makes use of a portable communication device. Since such vulnerable road users are often involved in accidents since they are not easily recognized in the traffic, the disclosure increases safety for these vulnerable road users. The method includes transferring position detecting sensor data or derived position data of the vulnerable road user transportation vehicle to the portable communication device which performs a map matching technique for refining the position data and transfers the refined position data to the vulnerable road user transportation vehicle. The vulnerable road user transportation vehicle distributes the refined position data to the surrounding transportation vehicles which calculate a trajectory for the vulnerable road user transportation vehicle and estimate the risk of a collision.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.

Abstract: A method for collision avoidance between a vulnerable road user transportation vehicle and a surrounding transportation vehicle. The user of the vulnerable road user transportation vehicle makes use of a portable communication device. Since such vulnerable road users are often involved in accidents since they are not easily recognized in the traffic, the disclosure increases safety for these vulnerable road users. The method includes transferring position detecting sensor data or derived position data of the vulnerable road user transportation vehicle to the portable communication device which performs a map matching technique for refining the position data and transfers the refined position data to the vulnerable road user transportation vehicle. The vulnerable road user transportation vehicle distributes the refined position data to the surrounding transportation vehicles which calculate a trajectory for the vulnerable road user transportation vehicle and estimate the risk of a collision.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.

Abstract: The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked through a triazole- or tetrazole linker to a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked through a triazole- or tetrazole linker to a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.

Abstract: The present invention is directed towards new 18F-folate radio-pharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety, which connects the condensed pyrimidine heterocycle to the amino acid portion within folate structures, as well as their precursors and their non-radioactive references, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.