Abstract: The present invention concerns novel Gram-negative bacteria efflux pump inhibitors. It further relates to the use of Gram-negative bacteria efflux pump inhibitors to prevent and/or treat antibiotic resistance by potentiating the activity of antibiotics. Infections by multidrug resistant (MDR) Gram-negative bacteria are a major threat to global healthcare. The inventors have discovered a novel class of Resistance Nodulation cell Division-efflux pump inhibitors. The inventors tested the effects of these inhibitors on growth inhibition of different bacteria as well as their impact on the boosting of antibiotic activity in different bacteria. Particularly, the inventors tested the effects of these inhibitors on E. coli, A. baumamnii, K. pneumoniae and P. aeruginosa.

Abstract: The present disclosure includes a system diagnosis method in an energy management system for electrical energy and at least one additional form of energy. The method includes acquiring actual values of one or more operating parameters; comparing the actual values with target values of the operating parameters in order to obtain a deviation; determining whether the deviation of the actual values of the operating parameters from the target values of the operating parameters exceeds a deviation threshold value; determining existence of a malfunction and where it is occurring when the deviation exceeds the deviation threshold value; assigning the malfunction to predefined malfunction groups based on the deviation; and producing a notification signal.

Abstract: A solid state power switch assembly of an aircraft solid state power controller includes a circuit board, at least one solid state power switch, and a busbar. The at least one solid state power switch has a first side and an opposing second side. A power switch electric contact surface is formed on the first side and the at least one solid state power switch is arranged on the circuit board with the second side facing the circuit board and the first side facing away from the circuit board. The busbar comprises at least one busbar contact portion configured for electrically contacting the power switch electric contact surface and at least one busbar mounting portion, which is configured for be mounted to the circuit board, so that the at least one solid state power switch is sandwiched between the at least one busbar contact portion and the circuit board.

Abstract: A shaped article, a method for making it, and its use. The shaped article is formed from flat fiber material and has a bottom (2), a body (4), and an opening, which is surrounded by a circumferential flange (6). The shaped article (1) comprises a flange stabilizer (10) attached to the second flat side (18) of the flange (6) facing the bottom (2). The flange stabilizer (10) is disc-shaped and has an inner contour (12) corresponding to the desired cross-sectional shape of the shaped article (1) in the region of the opening and can be slipped over the body (4) in the region of the bottom (2) and up to the flange (6). The flat sides (16, 18) of the flange stabilizer (10) extend essentially parallel to the flange (6), defining and stabilizing the cross-sectional shape of the body (4) in the region of the opening and the flange.

Abstract: A component of a brake for a vehicle, having a metallic base body with a surface provided with a coating which includes an intermediate layer lying on the base body and a covering layer lying on the intermediate layer. The covering layer is formed from a stainless steel matrix with hard material particles embedded therein. The hard material particles embedded in the stainless steel matrix have an average grain diameter of 10-125 ?m and have a non-melted core region consisting of uninfluenced material of the hard material particles, which core region is surrounded at least in sections by a mixing zone formed from material of the stainless steel matrix and material of the respective hard material particle, via which mixing zone the hard material particles are in each case materially bonded to the stainless steel matrix. Also, a method by which a component coated in this way is produced.

Abstract: A transmission unit, a vehicle powertrain and a vehicle are provided. The transmission unit comprises a first transmission shaft forming an input shaft of the transmission unit, and a second transmission shaft comprising a first shaft portion and a second shaft portion. The first shaft portion is rotatably connected to the first transmission shaft via a first gear wheel pair. The transmission unit further comprises a third transmission shaft rotatably connectable to the first shaft portion via a second gear wheel pair and rotatably connectable to the second shaft portion via a third gear wheel pair. The second and third gear wheel pairs are arranged at a distance from each other in a direction parallel to the longitudinal axis of the second transmission shaft such that, when the transmission unit is arranged in the vehicle powertrain, an electrical machine may be arranged therebetween.

Abstract: A transmission unit, a vehicle powertrain comprising the transmission unit and a vehicle are disclosed. The transmission unit comprises a first transmission shaft comprising a first gear wheel, and a second transmission shaft comprising a second gear wheel and a third gear wheel. The second gear wheel is arranged to cooperate with the first gear wheel. The transmission unit further comprises a third transmission shaft comprising a fourth gear wheel, the fourth gear wheel being arranged to cooperate with the third gear wheel. The third transmission shaft further comprises a fifth gear wheel arranged to be selectively connectable to the third transmission shaft for rotation therewith. The fifth gear wheel is arranged to cooperate with the second gear wheel. The transmission unit may be incorporated in a transmission arrangement further comprising a planetary gearbox unit.

Abstract: A method is disclosed for determining mechanical robustness of an overhead stowage bin for an aircraft includes repeatedly effecting an impact of a test body against an impact surface of the overhead stowage bin with a predefined impact force by a robotic arm of a manipulator, and investigating damage parameters of the overhead stowage bin.

Abstract: A component of a brake for a vehicle, having a metallic base body with a surface provided with a coating which includes an intermediate layer lying on the base body and a covering layer lying on the intermediate layer. The covering layer is formed from a stainless steel matrix with hard material particles embedded therein. The hard material particles embedded in the stainless steel matrix have an average grain diameter of 10-125 ?m and have a non-melted core region consisting of uninfluenced material of the hard material particles, which core region is surrounded at least in sections by a mixing zone formed from material of the stainless steel matrix and material of the respective hard material particle, via which mixing zone the hard material particles are in each case materially bonded to the stainless steel matrix. Also, a method by which a component coated in this way is produced.

Abstract: An electric motor, in particular for a vacuum pump, with two magnetically coupled shafts. A correction force can be set on each shaft by means of adjusting magnet devices, whereby negative effects due to errors in the magnetic coupling can be compensated.

Abstract: The invention relates to a die for arrangement in a press, wherein the die extends along an axial direction between two end faces and forms an inner peripheral surface between the end faces, wherein the die extends from the inner peripheral surface along a radial direction toward an outer peripheral surface and toward at least one centering surface that is disposed in the radial direction on a first diameter, wherein the die has a pressing zone that is spaced apart from the end faces and, in the vicinity of the pressing zone, the die has a greater maximum first stiffness, at least relative to zones of the die that are arranged on the end faces, compared to a pressing force acting on the inner peripheral surface in a direction of a normal vector, and wherein the maximum first stiffness is at least 10% greater than a minimum second stiffness that is present in at least one zone that is arranged on one of the end faces.

Abstract: An unbalance exciter for a vibratory plate includes a rotatably mounted unbalance shaft, on which an unbalance mass is provided. The exciter includes an exciter housing for the unbalance shaft, at least two bearing devices for the rotatable mounting of the unbalance shaft, and two bearing seats for the bearing devices. The exciter housing has a central part and two end parts arranged at the ends of the central part. The central part has a hollow-cylindrical recess in which a bearing point is provided for each of the bearing devices. The the central part is designed to optionally accommodate an unbalance shaft for either a first drive type in which the unbalance exciter can be driven by a drive device provided outside the exciter housing, or a second drive type in which the unbalance exciter can be driven by a drive device provided inside the exciter housing.

Abstract: At least one image of an interior of a vehicle is captured by at least one camera present in the vehicle. Image data of the at least one image that are denoted in reference to the vehicle are transmitted to an external server. A user is authorized by the external server to access the image data denoted in reference to the vehicle, for display to the user via VR goggles. An object detected by numerical methods is highlighted in color in the image depicted in the VR goggles.

Abstract: A shaped article, a method for making it, and its use. The shaped article is formed from flat fiber material and has a bottom (2), a body (4), and an opening, which is surrounded by a circumferential flange (6). The shaped article (1) comprises a flange stabilizer (10) attached to the second flat side (18) of the flange (6) facing the bottom (2). The flange stabilizer (10) is disc-shaped and has an inner contour (12) corresponding to the desired cross-sectional shape of the shaped article (1) in the region of the opening and can be slipped over the body (4) in the region of the bottom (2) and up to the flange (6). The flat sides (16, 18) of the flange stabilizer (10) extend essentially parallel to the flange (6), defining and stabilizing the cross-sectional shape of the body (4) in the region of the opening and the flange.

Abstract: In a method for aligning a polarization-maintaining optical fiber, in which the optical fiber (7a, 7b, 7c) is held in clamping fashion by means of a clamping device (12, 19, 23), a given rotational position of the optical fiber (7a, 7b, 7c) about the fiber longitudinal axis is detected, and the optical fiber (7a, 7b, 7c) is rotated about the fiber longitudinal axis by means of the clamping device (12, 19, 23), it is proposed that at least one clamping element (13, 14, 20-22, 24-27) of the clamping device (12, 19, 23), said clamping element abutting against the optical fiber (7a, 7b, 7c), is moved relative to at least one further clamping element (13, 14, 20-22, 24-27) of the clamping device (12, 13, 17), said at least one further clamping element likewise abutting against the optical fiber (7a, 7b, 7c), for the purposes of rotating the optical fiber (7a, 7b, 7c). Moreover, a correspondingly configured apparatus is presented.

Abstract: A composition contains at least one microorganism which can form a phosphate or carbonate precipitate in an alkaline medium, and at least one calcium source. The composition has at least one silicon compound having at least one Si-atom, at least one C-atom, and at least one H-atom. The composition can be used in a method for producing a construction product.

Abstract: A plate heat exchanger includes a stack of plate pairs arranged within a housing. Comb-like baffles extend into flow gaps between the plate pairs to direct a fluid flow in a sinusoidal pattern within the flow gaps. The flow gaps are divided into two sub-sets of flow gaps, preferably alternatingly arranged along the height of the stack. Legs of some baffles extend into a first sub-set but not into the second sub-set, while legs of some baffles extend into the second sub-set but not into the first sub-set. The baffles are arranged so that the sinusoidal pattern in the second sub-set is phase-shifted form the sinusoidal pattern in the first sub-set.

Abstract: A method is disclosed for determining mechanical robustness of an overhead stowage bin for an aircraft includes repeatedly effecting an impact of a test body against an impact surface of the overhead stowage bin with a predefined impact force by a robotic arm of a manipulator, and investigating damage parameters of the overhead stowage bin.

Abstract: At least one image of an interior of a vehicle is captured by at least one camera present in the vehicle. Image data of the at least one image that are denoted in reference to the vehicle are transmitted to an external server. A user is authorized by the external server to access the image data denoted in reference to the vehicle, for display to the user via VR goggles. An object detected by numerical methods is highlighted in color in the image depicted in the VR goggles.

Abstract: The invention relates to a die for arrangement in a press, wherein the die extends along an axial direction between two end faces and forms an inner peripheral surface between the end faces, wherein the die extends from the inner peripheral surface along a radial direction toward an outer peripheral surface and toward at least one centering surface that is disposed in the radial direction on a first diameter, wherein the die has a pressing zone that is spaced apart from the end faces and, in the vicinity of the pressing zone, the die has a greater maximum first stiffness, at least relative to zones of the die that are arranged on the end faces, compared to a pressing force acting on the inner peripheral surface in a direction of a normal vector, and wherein the maximum first stiffness is at least 10% greater than a minimum second stiffness that is present in at least one zone that is arranged on one of the end faces.