Patents by Inventor Tobias Rau
Tobias Rau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240142213Abstract: A measurement device includes a measurement head configured to capture dimensional measurement data of a measurement object. A guide structure is configured to move and guide at least one of the measurement head and the measurement object in a measurement volume of the measurement device. A measurement unit is configured to capture positional data of the guide structure based on which a pose of the measurement head can be calculated. Multiple temperature sensor units are configured to capture temperature data about the measurement volume. Each temperature sensor unit includes a carrier element, a temperature sensor connected to the carrier element, and a heating element connected to the carrier element. A control system is configured to process the dimensional measurement data and the positional data and, based on the temperature data, correct at least one of the dimensional measurement data and the positional data.Type: ApplicationFiled: October 29, 2023Publication date: May 2, 2024Inventors: Johannes Geiger, Tobias Perkhuhn, Alwine Schroll, Matthias Wahl, Sabrina Rau, Malte Langmack
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Patent number: 11926666Abstract: The present invention relates to a bispecific antibody construct comprising a first human binding domain which binds to human CDH3 on the surface of a target cell and a second binding domain which binds to human CDS on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.Type: GrantFiled: May 3, 2021Date of Patent: March 12, 2024Assignee: AMGEN RESEARCH (MUNICH) GMBHInventors: Bertram Weiss, Anna-Lena Frisk, Ruprecht Zierz, Peter Kufer, Tobias Raum, Doris Rau, Jonas Anlahr, Ralf Lutterbüse, Lisa Nahrwold, Christoph Dahlhoff, Claudia Blümel, Patrick Hoffmann
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Patent number: 11925684Abstract: The present invention relates to uses of bispecific antibodies exhibiting cross-species specificity for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of the same in non-human species and humans. The present invention moreover relates to methods for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of said bispecific antibodies exhibiting cross-species specificity. The present invention also relates to methods of measuring the biological activity and/or efficacy of such bispecific antibodies exhibiting cross-species specificity. In addition, the present invention relates to pharmaceutical compositions comprising bispecific single chain antibodies exhibiting cross-species specificity and to methods for the preparation of pharmaceutical compositions comprising said bispecific single chain antibodies exhibiting cross-species specificity for the treatment of diseases.Type: GrantFiled: August 29, 2018Date of Patent: March 12, 2024Assignee: AMGEN RESEARCH (MUNICH) GMBHInventors: Roman Kischel, Tobias Raum, Bernd Schlereth, Doris Rau, Ronny Cierpka, Peter Kufer
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Patent number: 11015499Abstract: An oil separator separates oil from aerosol in a combustion engine. The oil separator includes a housing having an inlet opening for the aerosol, an impeller which can be rotatably driven about a rotational axis, and which is adapted for generating an aerosol flow along an axial direction of the impeller and arranged in the housing, and an impact wall which is designed in such a way that a projection of the impeller oriented axially and downstream in the air flow impinges on the impact wall. At least one part of a projection of the impeller oriented axially and downstream in the air flow impinges on the inlet opening.Type: GrantFiled: November 13, 2018Date of Patent: May 25, 2021Assignee: Bayerische Motoren Werke AktiengesellschaftInventor: Tobias Rau
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Publication number: 20190078475Abstract: An oil separator separates oil from aerosol in a combustion engine. The oil separator includes a housing having an inlet opening for the aerosol, an impeller which can be rotatably driven about a rotational axis, and which is adapted for generating an aerosol flow along an axial direction of the impeller and arranged in the housing, and an impact wall which is designed in such a way that a projection of the impeller oriented axially and downstream in the air flow impinges on the impact wall. At least one part of a projection of the impeller oriented axially and downstream in the air flow impinges on the inlet opening.Type: ApplicationFiled: November 13, 2018Publication date: March 14, 2019Inventor: Tobias RAU
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Patent number: 8731680Abstract: Therapeutic system with implantable therapeutic unit (ITU) comprising control unit (CU), memory, telemetry unit connected (in)directly to CU for wireless bidirectional transmission of data to/from external device (ED) and detection unit for detecting physiological patient data or operational data. CU triggers outgoing data transmission (DT) from ITU to ED based on preselected internal events and establishes standby mode for reception on part of telemetry unit for receiving beginning (header) of incoming DT from ED to therapeutic unit exclusively within preselected response time window after DT from ITU to ED.Type: GrantFiled: April 16, 2008Date of Patent: May 20, 2014Assignee: Biotronik CRM Patent AGInventors: Joachim Reinke, Joern Bungartz, Volker Kukla, Tobias Rau
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Patent number: 8350058Abstract: The invention relates to a method for producing alkenyl succinic anhydrides of formula (1), in which R represents a C4 to C250 alkylene radical that can be linear or branched. The method involves the reaction of maleic acid, maleic anhydride, fumaric acid or esters thereof and an alkene which contains 4-250 carbon atoms at from 150 to 250° C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator.Type: GrantFiled: December 3, 2005Date of Patent: January 8, 2013Assignee: Clariant Produkte (Deutschland) GmbHInventors: Dirk Leinweber, Tobias Rau
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Patent number: 8205753Abstract: This invention relates to the use of a compound of the formula (I) where R1 is a hydrocarbon group having 1-40 carbon atoms, R2 is an aliphatic hydrocarbon group having 2-4 carbon atoms, and also R3 is an alkoxy group, n is in the range from 1 to 50, and m is 1 or 2, as flotation reagent in silicate flotation R1—O—R2—NH(2-m)—[(R3)n—H]m??(I).Type: GrantFiled: February 26, 2007Date of Patent: June 26, 2012Assignee: Clariant Finance (BVI) LimitedInventors: Klaus-Ulrich Pedain, Tobias Rau
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Patent number: 8172089Abstract: The invention relates to the use of a compound of formula R—N-[A-NH2]2??(1) wherein R represents a linear or branched alkyl group or alkenyl group having 6 to 20 carbon atoms while A represents a C2 to C4 alkylene group, as collector in silicate flotation.Type: GrantFiled: April 16, 2007Date of Patent: May 8, 2012Assignee: Clarient Finance (BVI) LimitedInventors: Klaus-Ulrich Pedain, Tobias Rau, Michael Patzke
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Patent number: 7695634Abstract: The present invention relates a flotation reagent for sulfidic ores, containing at least one compound of formula (1), wherein R2, R3, R4, R5, R6 and R7, independent of one another, represent hydrogen or groups containing 1 to 15 carbon atoms or groups containing oxygen or nitrogen, and at least another compound serving as collector and containing at least one sulfur atom that is directly bound to a carbon or phosphorus atom, wherein the carbon or phosphorus atom is directly bound to at least another sulfur atom or an oxygen atom.Type: GrantFiled: April 28, 2005Date of Patent: April 13, 2010Assignee: Clariant Produkte (Deutschland) GmbHInventors: Heinrich Hesse, Tobias Rau, Wolfgang Buch, Jaime Gomez, Miguel Angel Arends, Norbert Ernstorfer
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Patent number: 7553984Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms. Also disclosed is the process for preparing the above compound.Type: GrantFiled: July 21, 2006Date of Patent: June 30, 2009Assignee: Clariant Produkte (Deutschland) GmbHInventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Angel Arends, Norbert Ernstorfer
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Publication number: 20090152174Abstract: The invention relates to the use of a compound of formula R—N-[A-NH2]2??(1) wherein R represents a linear or branched alkyl group or alkenyl group having 6 to 20 carbon atoms while A represents a C2 to C4 alkylene group, as collector in silicate flotation.Type: ApplicationFiled: April 16, 2007Publication date: June 18, 2009Applicant: CLARIANT INTERNATIONAL LTD.Inventors: Klaus-Ulrich Pedian, Tobias Rau, Michael Patzke
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Publication number: 20090114573Abstract: This invention relates to the use of a compound of the formula (I) where R1 is a hydrocarbon group having 1-40 carbon atoms, R2 is an aliphatic hydrocarbon group having 2-4 carbon atoms, and also R3 is an alkoxy group, n is in the range from 1 to 50, and m is 1 or 2, as flotation reagent in silicate flotation R1—O—R2—NH(2-m)—[(R3)n—H]m??(I)Type: ApplicationFiled: February 26, 2007Publication date: May 7, 2009Inventors: Klaus-Ulrich Pedain, Tobias Rau
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Publication number: 20080262572Abstract: Therapeutic system with implantable therapeutic unit (ITU) comprising control unit (CU), memory, telemetry unit connected (in)directly to CU for wireless bidirectional transmission of data to/from external device (ED) and detection unit for detecting physiological patient data or operational data. CU triggers outgoing data transmission (DT) from ITU to ED based on preselected internal events and establishes standby mode for reception on part of telemetry unit for receiving beginning (header) of incoming DT from ED to therapeutic unit exclusively within preselected response time window after DT from ITU to ED.Type: ApplicationFiled: April 16, 2008Publication date: October 23, 2008Inventors: Joachim REINKE, Joern Bungartz, Volker Kukla, Tobias Rau
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Publication number: 20080108836Abstract: The invention relates to a method for producing alkenyl succinic anhydrides of formula (1), in which R represents a C4 to C250 alkylene radical that can be linear or branched. The method involves the reaction of maleic acid, maleic anhydride, fumaric acid or esters thereof and an alkene which contains 4-250 carbon atoms at from 150 to 250° C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator.Type: ApplicationFiled: December 3, 2005Publication date: May 8, 2008Inventors: Dirk Leinweber, Tobias Rau
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Publication number: 20070221878Abstract: The present invention relates a flotation reagent for sulfidic ores, containing at least one compound of formula (1), wherein R2, R3, R4, R5, R6 and R7, independent of one another, represent hydrogen or groups containing 1 to 15 carbon atoms or groups containing oxygen or nitrogen, and at least another compound serving as collector and containing at least one sulfur atom that is directly bound to a carbon or phosphorus atom, wherein the carbon or phosphorus atom is directly bound to at least another sulfur atom or an oxygen atom.Type: ApplicationFiled: April 28, 2005Publication date: September 27, 2007Inventors: Heinrich Hesse, Tobias Rau, Wolfgang Buch, Jaime Gomez, Miguel Arends, Norbert Ernstorfer
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Publication number: 20070181467Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms. Also disclosed is the process for preparing the above compound.Type: ApplicationFiled: July 21, 2006Publication date: August 9, 2007Inventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Arends, Norbert Ernstorfer
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Patent number: 7104404Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms.Type: GrantFiled: July 22, 2003Date of Patent: September 12, 2006Assignee: Clariant GmbHInventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Angel Arends, Norbert Ernstorfer
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Publication number: 20060032799Abstract: The invention relates to a composition which is effective as a flotation reagent for collecting and separating potash salt mixtures. The flotation reagent comprises A) at least one compound of the formula [R1—NH3]+X?, where R1 is a C8 to C22 alkyl radical and X? is an anion, and B) a branched fatty acid having a chain length of 8 to 22 carbon atoms.Type: ApplicationFiled: March 7, 2003Publication date: February 16, 2006Inventors: Klaus-Ulrich Pedain, Tobias Rau
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Publication number: 20050263442Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms.Type: ApplicationFiled: July 22, 2003Publication date: December 1, 2005Inventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Arends, Norbert Ernstorfer