Patents by Inventor Tobias Rau

Tobias Rau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240142213
    Abstract: A measurement device includes a measurement head configured to capture dimensional measurement data of a measurement object. A guide structure is configured to move and guide at least one of the measurement head and the measurement object in a measurement volume of the measurement device. A measurement unit is configured to capture positional data of the guide structure based on which a pose of the measurement head can be calculated. Multiple temperature sensor units are configured to capture temperature data about the measurement volume. Each temperature sensor unit includes a carrier element, a temperature sensor connected to the carrier element, and a heating element connected to the carrier element. A control system is configured to process the dimensional measurement data and the positional data and, based on the temperature data, correct at least one of the dimensional measurement data and the positional data.
    Type: Application
    Filed: October 29, 2023
    Publication date: May 2, 2024
    Inventors: Johannes Geiger, Tobias Perkhuhn, Alwine Schroll, Matthias Wahl, Sabrina Rau, Malte Langmack
  • Patent number: 11926666
    Abstract: The present invention relates to a bispecific antibody construct comprising a first human binding domain which binds to human CDH3 on the surface of a target cell and a second binding domain which binds to human CDS on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: March 12, 2024
    Assignee: AMGEN RESEARCH (MUNICH) GMBH
    Inventors: Bertram Weiss, Anna-Lena Frisk, Ruprecht Zierz, Peter Kufer, Tobias Raum, Doris Rau, Jonas Anlahr, Ralf Lutterbüse, Lisa Nahrwold, Christoph Dahlhoff, Claudia Blümel, Patrick Hoffmann
  • Patent number: 11925684
    Abstract: The present invention relates to uses of bispecific antibodies exhibiting cross-species specificity for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of the same in non-human species and humans. The present invention moreover relates to methods for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of said bispecific antibodies exhibiting cross-species specificity. The present invention also relates to methods of measuring the biological activity and/or efficacy of such bispecific antibodies exhibiting cross-species specificity. In addition, the present invention relates to pharmaceutical compositions comprising bispecific single chain antibodies exhibiting cross-species specificity and to methods for the preparation of pharmaceutical compositions comprising said bispecific single chain antibodies exhibiting cross-species specificity for the treatment of diseases.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: March 12, 2024
    Assignee: AMGEN RESEARCH (MUNICH) GMBH
    Inventors: Roman Kischel, Tobias Raum, Bernd Schlereth, Doris Rau, Ronny Cierpka, Peter Kufer
  • Patent number: 11015499
    Abstract: An oil separator separates oil from aerosol in a combustion engine. The oil separator includes a housing having an inlet opening for the aerosol, an impeller which can be rotatably driven about a rotational axis, and which is adapted for generating an aerosol flow along an axial direction of the impeller and arranged in the housing, and an impact wall which is designed in such a way that a projection of the impeller oriented axially and downstream in the air flow impinges on the impact wall. At least one part of a projection of the impeller oriented axially and downstream in the air flow impinges on the inlet opening.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: May 25, 2021
    Assignee: Bayerische Motoren Werke Aktiengesellschaft
    Inventor: Tobias Rau
  • Publication number: 20190078475
    Abstract: An oil separator separates oil from aerosol in a combustion engine. The oil separator includes a housing having an inlet opening for the aerosol, an impeller which can be rotatably driven about a rotational axis, and which is adapted for generating an aerosol flow along an axial direction of the impeller and arranged in the housing, and an impact wall which is designed in such a way that a projection of the impeller oriented axially and downstream in the air flow impinges on the impact wall. At least one part of a projection of the impeller oriented axially and downstream in the air flow impinges on the inlet opening.
    Type: Application
    Filed: November 13, 2018
    Publication date: March 14, 2019
    Inventor: Tobias RAU
  • Patent number: 8731680
    Abstract: Therapeutic system with implantable therapeutic unit (ITU) comprising control unit (CU), memory, telemetry unit connected (in)directly to CU for wireless bidirectional transmission of data to/from external device (ED) and detection unit for detecting physiological patient data or operational data. CU triggers outgoing data transmission (DT) from ITU to ED based on preselected internal events and establishes standby mode for reception on part of telemetry unit for receiving beginning (header) of incoming DT from ED to therapeutic unit exclusively within preselected response time window after DT from ITU to ED.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: May 20, 2014
    Assignee: Biotronik CRM Patent AG
    Inventors: Joachim Reinke, Joern Bungartz, Volker Kukla, Tobias Rau
  • Patent number: 8350058
    Abstract: The invention relates to a method for producing alkenyl succinic anhydrides of formula (1), in which R represents a C4 to C250 alkylene radical that can be linear or branched. The method involves the reaction of maleic acid, maleic anhydride, fumaric acid or esters thereof and an alkene which contains 4-250 carbon atoms at from 150 to 250° C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator.
    Type: Grant
    Filed: December 3, 2005
    Date of Patent: January 8, 2013
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Dirk Leinweber, Tobias Rau
  • Patent number: 8205753
    Abstract: This invention relates to the use of a compound of the formula (I) where R1 is a hydrocarbon group having 1-40 carbon atoms, R2 is an aliphatic hydrocarbon group having 2-4 carbon atoms, and also R3 is an alkoxy group, n is in the range from 1 to 50, and m is 1 or 2, as flotation reagent in silicate flotation R1—O—R2—NH(2-m)—[(R3)n—H]m??(I).
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: June 26, 2012
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Klaus-Ulrich Pedain, Tobias Rau
  • Patent number: 8172089
    Abstract: The invention relates to the use of a compound of formula R—N-[A-NH2]2??(1) wherein R represents a linear or branched alkyl group or alkenyl group having 6 to 20 carbon atoms while A represents a C2 to C4 alkylene group, as collector in silicate flotation.
    Type: Grant
    Filed: April 16, 2007
    Date of Patent: May 8, 2012
    Assignee: Clarient Finance (BVI) Limited
    Inventors: Klaus-Ulrich Pedain, Tobias Rau, Michael Patzke
  • Patent number: 7695634
    Abstract: The present invention relates a flotation reagent for sulfidic ores, containing at least one compound of formula (1), wherein R2, R3, R4, R5, R6 and R7, independent of one another, represent hydrogen or groups containing 1 to 15 carbon atoms or groups containing oxygen or nitrogen, and at least another compound serving as collector and containing at least one sulfur atom that is directly bound to a carbon or phosphorus atom, wherein the carbon or phosphorus atom is directly bound to at least another sulfur atom or an oxygen atom.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: April 13, 2010
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Heinrich Hesse, Tobias Rau, Wolfgang Buch, Jaime Gomez, Miguel Angel Arends, Norbert Ernstorfer
  • Patent number: 7553984
    Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms. Also disclosed is the process for preparing the above compound.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: June 30, 2009
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Angel Arends, Norbert Ernstorfer
  • Publication number: 20090152174
    Abstract: The invention relates to the use of a compound of formula R—N-[A-NH2]2??(1) wherein R represents a linear or branched alkyl group or alkenyl group having 6 to 20 carbon atoms while A represents a C2 to C4 alkylene group, as collector in silicate flotation.
    Type: Application
    Filed: April 16, 2007
    Publication date: June 18, 2009
    Applicant: CLARIANT INTERNATIONAL LTD.
    Inventors: Klaus-Ulrich Pedian, Tobias Rau, Michael Patzke
  • Publication number: 20090114573
    Abstract: This invention relates to the use of a compound of the formula (I) where R1 is a hydrocarbon group having 1-40 carbon atoms, R2 is an aliphatic hydrocarbon group having 2-4 carbon atoms, and also R3 is an alkoxy group, n is in the range from 1 to 50, and m is 1 or 2, as flotation reagent in silicate flotation R1—O—R2—NH(2-m)—[(R3)n—H]m??(I)
    Type: Application
    Filed: February 26, 2007
    Publication date: May 7, 2009
    Inventors: Klaus-Ulrich Pedain, Tobias Rau
  • Publication number: 20080262572
    Abstract: Therapeutic system with implantable therapeutic unit (ITU) comprising control unit (CU), memory, telemetry unit connected (in)directly to CU for wireless bidirectional transmission of data to/from external device (ED) and detection unit for detecting physiological patient data or operational data. CU triggers outgoing data transmission (DT) from ITU to ED based on preselected internal events and establishes standby mode for reception on part of telemetry unit for receiving beginning (header) of incoming DT from ED to therapeutic unit exclusively within preselected response time window after DT from ITU to ED.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 23, 2008
    Inventors: Joachim REINKE, Joern Bungartz, Volker Kukla, Tobias Rau
  • Publication number: 20080108836
    Abstract: The invention relates to a method for producing alkenyl succinic anhydrides of formula (1), in which R represents a C4 to C250 alkylene radical that can be linear or branched. The method involves the reaction of maleic acid, maleic anhydride, fumaric acid or esters thereof and an alkene which contains 4-250 carbon atoms at from 150 to 250° C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator.
    Type: Application
    Filed: December 3, 2005
    Publication date: May 8, 2008
    Inventors: Dirk Leinweber, Tobias Rau
  • Publication number: 20070221878
    Abstract: The present invention relates a flotation reagent for sulfidic ores, containing at least one compound of formula (1), wherein R2, R3, R4, R5, R6 and R7, independent of one another, represent hydrogen or groups containing 1 to 15 carbon atoms or groups containing oxygen or nitrogen, and at least another compound serving as collector and containing at least one sulfur atom that is directly bound to a carbon or phosphorus atom, wherein the carbon or phosphorus atom is directly bound to at least another sulfur atom or an oxygen atom.
    Type: Application
    Filed: April 28, 2005
    Publication date: September 27, 2007
    Inventors: Heinrich Hesse, Tobias Rau, Wolfgang Buch, Jaime Gomez, Miguel Arends, Norbert Ernstorfer
  • Publication number: 20070181467
    Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms. Also disclosed is the process for preparing the above compound.
    Type: Application
    Filed: July 21, 2006
    Publication date: August 9, 2007
    Inventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Arends, Norbert Ernstorfer
  • Patent number: 7104404
    Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: September 12, 2006
    Assignee: Clariant GmbH
    Inventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Angel Arends, Norbert Ernstorfer
  • Publication number: 20060032799
    Abstract: The invention relates to a composition which is effective as a flotation reagent for collecting and separating potash salt mixtures. The flotation reagent comprises A) at least one compound of the formula [R1—NH3]+X?, where R1 is a C8 to C22 alkyl radical and X? is an anion, and B) a branched fatty acid having a chain length of 8 to 22 carbon atoms.
    Type: Application
    Filed: March 7, 2003
    Publication date: February 16, 2006
    Inventors: Klaus-Ulrich Pedain, Tobias Rau
  • Publication number: 20050263442
    Abstract: A method for the flotation of sulfide ores is disclosed. The method comprises contacting the sulfide ores with a composition comprising at least one compound of the formula where R1, R2 and R3 independently of one another are alkyl groups having 1 to 18 carbon atoms, alkenyl groups having 2 to 18 carbon atoms, aryl groups having 6 to 10 carbon atoms, or alkylaryl groups having 7 to 10 carbon atoms.
    Type: Application
    Filed: July 22, 2003
    Publication date: December 1, 2005
    Inventors: Tobias Rau, Heinrich Hesse, Wolfgang Buch, Jaime Gomez, Miguel Arends, Norbert Ernstorfer