Patents by Inventor Tobias Söderman
Tobias Söderman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10864512Abstract: The invention discloses a separation matrix for purification of biomacromolecules, comprising a plurality of particles (1) having a core region (2) and a shell region (3), wherein: a) said shell region is accessible to a target biomacromolecule; b) said core region is less accessible to the target biomacromolecule than the shell region; and c) the core region comprises a grafted polymer comprising residues of at least one polymerizable monomer.Type: GrantFiled: March 30, 2017Date of Patent: December 15, 2020Assignee: Cytiva BioProcess R&D ABInventors: Jean-Luc Maloisel, Tobias Söderman, Ola Lind, Ida Eklind
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Publication number: 20190111419Abstract: The invention discloses a separation matrix for purification of biomacromolecules, comprising a plurality of particles (1) having a core region (2) and a shell region (3), wherein: a) said shell region is accessible to a target biomacromolecule; b) said core region is less accessible to the target biomacromolecule than the shell region; and c) the core region comprises a grafted polymer comprising residues of at least one polymerizable monomer.Type: ApplicationFiled: March 30, 2017Publication date: April 18, 2019Inventors: Jean-Luc Maloisel, Tobias Söderman, Ola Lind, Ida Eklind
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Patent number: 8600684Abstract: The present invention relates to a method for determining the identity of a microfluidic device and a home position by means of a set of home position marks on the microfluidic device, which is of the type used in a microfluidic system. Said method comprises following phases: a microfluidic device scanning phase, wherein a microfluidic device is scanned for mark identifiers; a microfluidic device identifying phase, wherein at least one a characteristic feature of the set of home marks is/are determined and used for identifying the identity of the microfluidic device; a home position determining phase, wherein the home position is determined by the use of at least a subset of the home position marks identified during said previous phases. The present invention relates to a set of home marks, a microfluidic device carrying such a set of home marks, a microfluidic system, a computer program product and a computer program on a computer usable medium.Type: GrantFiled: May 31, 2006Date of Patent: December 3, 2013Assignee: Gyros Patent ABInventors: Agneta Ohlström, Mårten Bergström, Tobias Söderman, Robert Bielik
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Publication number: 20090308470Abstract: The present invention relates to a method for determining the identity of a microfluidic device and a home position by means of a set of home position marks on the microfluidic device, which is of the type used in a microfluidic system. Said method comprises following phases: a microfluidic device scanning phase, wherein a microfluidic device is scanned for mark identifiers; a microfluidic device identifying phase, wherein at least one a characteristic feature of the set of home marks is/are determined and used for identifying the identity of the microfluidic device; a home position determining phase, wherein the home position is determined by the use of at least a subset of the home position marks identified during said previous phases. The present invention relates to a set of home marks, a microfluidic device carrying such a set of home marks, a microfluidic system, a computer program product and a computer program on a computer usable medium.Type: ApplicationFiled: May 31, 2006Publication date: December 17, 2009Applicant: GYROS Patent ABInventors: Mårten Bergström, Robert Bielik, Tobias Söderman, Agneta Ohlström
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Patent number: 7616791Abstract: The present invention relates to a method, a system, a neural network and a computer program product for determining the quality of an analytical process, preferably the confidence value. The analytical process is performed in a microchannel structure of a microfluidic device, from which data information of the analytic process is acquired by scanning at least one search area of the microchannel structure for signal data. The search area comprises the result of the analytical process and the acquired data information is stored as an image, one image for each scanned search area.Type: GrantFiled: June 30, 2004Date of Patent: November 10, 2009Assignee: Gyros Patent ABInventors: Tobias Söderman, Mats Inganäs
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Patent number: 7148264Abstract: The present invention relates to a method of producing one or more macroporous cross-linked polymer particles, which comprises polymerization and cross-linking of divinyl ether monomers in an inert solvent, in which method the polymerization is free radical initiated. The invention also relates to particles so produced, which are useful as separation medium e.g. in RPC or, after suitable derivatization, in other chromatographic methods.Type: GrantFiled: August 9, 2004Date of Patent: December 12, 2006Assignee: GE Healthcare Bio-Sciences ABInventors: Tobias Söderman, Anders Larsson, Philippe Busson
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Publication number: 20060249457Abstract: The present invention relates to a separation matrix comprised of a support to the surfaces of which polymer chains have been coupled, wherein each polymer chain presents recurring proton-donating groups and at least the surface of the support is substantially hydrophilic. In the most advantageous embodiment, the support is porous cross-linked agarose, the polymers are poly(acrylic acid) and the proton-donating groups are carboxyl groups. The matrix is useful e.g. to remove PEG from pegylated and/or native compounds in a liquid. Accordingly, the invention also encompasses a method, such as a chromatographic method, wherein the separation matrix according to the invention is used, for example as a pre-treatment of a reaction mixture that comprises unreacted PEG, pegylated proteins and native proteins.Type: ApplicationFiled: September 6, 2004Publication date: November 9, 2006Inventors: James Van Alstine, Jan Bergström, Henrik Ihre, Tobias Söderman
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Patent number: 6878555Abstract: A method for dispensing droplets of a liquid to a microsystem in the form of a disc comprising a target area (TA0I) in its surface, said disc preferably being a microfluidic disc comprising a microchannel structure with an inlet port that is a target area (TA0I). The method is characterized by comprising the steps of: i) providing (1) said disc which has a triggering mark, and (2) a dispenser arrangement comprising: a) a spinner for rotating the disc around its axis, b) a drop dispenser permitting dispensation of droplets to inlet port I, c) a fixed trigger position outside the disc, and d) a controller which is capable of triggering the dispensation of a droplet into (TA0I) as a function of the triggering mark passing the trigger position, ii) placing the disc in the spinner and programming the controller with values for dispensing parameters that will give dispensation of the droplets to TA0I, iii) dispensing the droplets. The invention also comprises the dispenser arrangement as such.Type: GrantFiled: December 6, 2001Date of Patent: April 12, 2005Assignee: Gyros ABInventors: Per Andersson, Gérald Jesson, Tobias Söderman, Jan Sjöberg