Abstract: An infusion system includes a catheter with a proximal end, distal end, at least one lumen between the proximal end and distal end, and outlets. Each outlet connects to the at least one lumen to convey fluid, and extends radially through a catheter wall of the catheter. The outlets are spaced apart from in the proximodistal direction, and include a first outlet and a second outlet. The first outlet is opened independently of a fluid pressure prevailing in the lumen in order to administer an analgesic. The second outlet is adapted for fluid pressure-dependent administration of the analgesic and capable of being converted, as a function of fluid pressure inside the lumen, between an opening state, in which the second outlet is opened to administer the analgesic, and a closure state, in which the second outlet is closed. The infusion system can be used in pain management.

Abstract: The disclosure relates to a package having a package lower part for receiving a product and having a lid part attached to the package lower part for closing the package. The lid part includes a label and a carrier layer section, wherein the label adheres to the carrier layer section, and wherein the lid part is adhered to the package lower part by means of the label. Furthermore, the disclosure relates to a method of manufacturing a package.

Abstract: An infusion system and method for providing different medical fluids to a patient. The infusion system, which can be used in complex infusion therapies, includes a catheter with a catheter tube and at least one lumen extending longitudinally through the catheter tube between a proximal tube end and a distal tube end. A plurality of pump devices are each connected to the at least one lumen so as to convey fluid. A control device is connected to the pump devices and adapted to control the pump devices so that the different medical fluids can be delivered through the at least one lumen by the pump devices in time division multiplex. The catheter can include the pump devices. Each pump device can be configured as a micropump mounted at the proximal tube end.

Abstract: A system for tracking a catheter in a patient. The system including a plurality of surface electrodes and a surface patch attached to the patient and a processor coupled to the plurality of surface electrodes and the surface patch. The processor determines a location of at least one of the plurality of surface electrodes, stores locations of the surface patch and the at least one of the plurality of surface electrodes, determines a three-dimensional shell shape that corresponds to a portion of the patient, determines a model of an impedance tracking field in at least a portion of the three-dimensional shell shape, injects current through one or more of the plurality of surface electrodes, fits measured voltages from the catheter to the model of the impedance tracking field to determine locations of the catheter, and provides therapy to the patient based on the locations of the catheter.

Abstract: A system for tracking a catheter in a patient. The system including a plurality of surface electrodes and a surface patch attached to the patient and a processor coupled to the plurality of surface electrodes and the surface patch. The processor determines a location of at least one of the plurality of surface electrodes, stores locations of the surface patch and the at least one of the plurality of surface electrodes, determines a three-dimensional shell shape that corresponds to a portion of the patient, determines a model of an impedance tracking field in at least a portion of the three-dimensional shell shape, injects current through one or more of the plurality of surface electrodes, fits measured voltages from the catheter to the model of the impedance tracking field to determine locations of the catheter, and provides therapy to the patient based on the locations of the catheter.

Abstract: A detection and identification system of instruments for use with a surgical navigation system is described. The navigation system contains an instrument assembly containing a coil (of a receiver) having an interior space, an instrument configured to be removably coupled to the coil, and a prong affixed to the instrument and configured to be at least partially disposed within the interior space of the coil when the instrument is coupled to the coil, where the prong has a length corresponding to physical dimensions of the instrument. The navigation system can also contain a transmitter located within the body of a patient.

Abstract: A method for simulating the development over time of bookings situations for flights. It is proposed that a first number of hard parameters which include at least one flight schedule between at least two departure and arrival points, and a second number of soft parameters which include at least one fare for a flight between the at least two departure and arrival points, are provided, as well as a virtual environment which constitutes a representation of a real environment in which virtual passengers book flights under conditions defined in each case by the parameters. The pattern over time of the totality of all bookings is recorded and can be displayed on a display device and wherein a user influences the respective bookings situations by prior adjustment of at least one of the soft parameters.

Abstract: Methods and systems are provided for an electromagnetic coil assembly for a surgical navigation tracking system which may be used during image-guided surgery. A medical instrument assembly for an electromagnetic surgical navigation system, may comprise a tracking sensor interface included within a handle of a medical instrument, the interface having a first mating surface. Further, the assembly may include a tracking sensor including a second mating surface and one or more electromagnetic coils, where the tracking sensor is removably coupled to the tracking sensor interface of the medical instrument via an attachment device included on one or more of the first mating surface and second mating surface.

Abstract: Minimally invasive systems and methods for navigation-assisted surgery are described. The system comprises a patient reference device and a transmitter. The patient reference device comprises a microsensor disposed at a distal end. The distal end is configured to pierce a patient's skin and to be anchored in a patient's anatomy. The microsensor is at least partially embedded in the patient's anatomy and is anchored proximate to a surgical field of interest. The transmitter is configured to be detachably attached to the patient's skin proximate to the surgical field of interest. The system establishes a global navigation reference frame by transmitting signals from the transmitter and receiving the signals with the microsensor to establish a position and an orientation of the microsensor to register a position and an orientation of the patient's anatomy within the global navigation reference frame. Other embodiments are described.

Abstract: A detection and identification system of instruments for use with a surgical navigation system is described. The navigation system contains an instrument assembly containing a coil (of a receiver) having an interior space, an instrument configured to be removably coupled to the coil, and a prong affixed to the instrument and configured to be at least partially disposed within the interior space of the coil when the instrument is coupled to the coil, where the prong has a length corresponding to physical dimensions of the instrument. The navigation system can also contain a transmitter located within the body of a patient.

Abstract: Electromagnetic tracking systems and methods for correcting hemispherical ambiguity are described. The system may include a single transmitter having three coils arranged in an industry-standard coil arrangement (ISCA). The tracking system may also contain a receiver having three coils arranged in an ISCA configuration, as well as a fourth coil having a different orientation then any of the other three coils of the receiver. The fourth coil may be used to determine the correct solution to the hemispherical ambiguity that can occur when tracking using two three-coil assemblies. Other embodiments are described.

Abstract: An identification system for surgical navigation is described. The navigation system contains an instrument assembly containing a coil (of a receiver) having an interior space, an instrument configured to be removably coupled to the coil, and a prong affixed to the instrument and configured to be at least partially disposed within the interior space of the coil when the instrument is coupled to the coil. The prong can have a length corresponding to the physical dimensions of the instrument. The navigation system can also contain a transmitter located within the body of a patient. The navigation system can be used to identify interchangeable instruments. Other embodiments are described.

Abstract: A method for simulating the development over time of bookings situations for flights. It is proposed that a first number of hard parameters which include at least one flight schedule between at least two departure and arrival points, and a second number of soft parameters which include at least one fare for a flight between the at least two departure and arrival points, are provided, as well as a virtual environment which constitutes a representation of a real environment in which virtual passengers book flights under conditions defined in each case by the parameters. The pattern over time of the totality of all bookings is recorded and can be displayed on a display device and wherein a user influences the respective bookings situations by prior adjustment of at least one of the soft parameters.