Patents by Inventor Tobias SPECK

Tobias SPECK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA VIRUSES FOR IMMUNOVIROTHERAPY
    Publication number: 20190099461
    Abstract: The present invention relates to a recombinant virus of the family Paramyxoviridae, comprising at least one expressible polynucleotide encoding a multispecific binding polypeptide, said multispecific binding polypeptide comprising a first binding domain binding to a surface molecule of an immune cell with antitumor activity, preferably a lymphocyte, more preferably a T cell or a dendritic cell, and a second binding domain binding to a tumor-associated antigen; to a polynucleotide encoding the same, and to a kit comprising the same. Moreover, the present invention relates to a method for treating cancer in a subject afflicted with cancer, comprising contacting said subject with a recombinant virus of the family Paramyxoviridae of the invention, and thereby, treating cancer in a subject afflicted with cancer.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 4, 2019
    Applicants: Deutsches Krebsforschungszentrum, RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
    Inventors: Guy UNGERECHTS, Tobias SPECK, Christine ENGELAND, Sascha BOSSOW
  • RNA viruses for immunovirotherapy
    Patent number: 10172894
    Abstract: The present invention relates to a recombinant virus of the family Paramyxoviridae, comprising at least one expressible polynucleotide encoding a multispecific binding polypeptide, said multispecific binding polypeptide comprising a first binding domain binding to a surface molecule of an immune cell with antitumor activity, preferably a lymphocyte, more preferably a T cell or a dendritic cell, and a second binding domain binding to a tumor-associated antigen; to a polynucleotide encoding the same, and to a kit comprising the same. Moreover, the present invention relates to a method for treating cancer in a subject afflicted with cancer, comprising contacting said subject with a recombinant virus of the family Paramyxoviridae of the invention, and thereby, treating cancer in a subject afflicted with cancer.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: January 8, 2019
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM, RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
    Inventors: Guy Ungerechts, Tobias Speck, Christine Engeland, Sascha Bossow
  • RNA VIRUSES FOR IMMUNOVIROTHERAPY
    Publication number: 20170128505
    Abstract: The present invention relates to a recombinant virus of the family Paramyxoviridae, comprising at least one expressible polynucleotide encoding a multispecific binding polypeptide, said multispecific binding polypeptide comprising a first binding domain binding to a surface molecule of an immune cell with antitumor activity, preferably a lymphocyte, more preferably a T cell or a dendritic cell, and a second binding domain binding to a tumor-associated antigen; to a polynucleotide encoding the same, and to a kit comprising the same. Moreover, the present invention relates to a method for treating cancer in a subject afflicted with cancer, comprising contacting said subject with a recombinant virus of the family Paramyxoviridae of the invention, and thereby, treating cancer in a subject afflicted with cancer.
    Type: Application
    Filed: August 25, 2016
    Publication date: May 11, 2017
    Inventors: Guy UNGERECHTS, Tobias SPECK, Christine ENGELAND, Sascha BOSSOW