Patents by Inventor Tobias THALER

Tobias THALER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphic form of N-{6-(hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide
    Patent number: 10759758
    Abstract: The present invention relates to crystalline forms of N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide, to processes for their preparation, to pharmaceutical compositions comprising them and to their use in the control of disorders.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: September 1, 2020
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias Thaler, Johannes Platzek, Nicolas Guimond
  • Synthesis of indazoles
    Patent number: 10633365
    Abstract: The present invention relates to a novel method of preparing a 2-substituted indazole of formula (I) to novel intermediate compounds, and to the use of intermediate compounds for the preparation of said 2-substituted indazole.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: April 28, 2020
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias Thaler, Johannes Platzek, Nicolas Guimond
  • Crystalline forms of N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide
    Patent number: 10501437
    Abstract: The present invention relates to crystalline forms of N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide, to processes for their preparation, to pharmaceutical compositions comprising them and to their use in the control of disorders.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: December 10, 2019
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias Thaler, Johannes Platzek, Nicolas Guimond
  • Synthesis of indazoles
    Patent number: 10501417
    Abstract: The present invention relates to a novel method of preparing a 2-substituted indazole of structure: (I), to intermediate compounds, and to the use of intermediate compounds for the preparation of said 2-substituted indazole.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: December 10, 2019
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias Thaler, Johannes Platzek, Nicolas Guimond
  • Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents
    Patent number: 10479765
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: November 19, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Beck, Tobias Thaler, Raimund Kast, Daniel Meibom, Mark Meininghaus, Carsten Terjung, Martina Delbeck, Klemens Lustig, Uwe Muenster, Britta Olenik
  • CRYSTALLINE FORMS OF N-[2-(3-HYDROXY-3-METHYLBUTYL)-6-(2-HYDROXYPROPAN-2-YL)-2H-INDAZOL-5-YL]-6-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE
    Publication number: 20190152944
    Abstract: The present invention relates to crystalline forms of N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide, to processes for their preparation, to pharmaceutical compositions comprising them and to their use in the control of disorders.
    Type: Application
    Filed: April 25, 2017
    Publication date: May 23, 2019
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias THALER, Johannes PLATZEK, Nicolas GUIMOND
  • SYNTHESIS OF INDAZOLES
    Publication number: 20190144420
    Abstract: The present invention relates to a novel method of preparing a 2-substituted indazole of formula (I) to novel intermediate compounds, and to the use of intermediate compounds for the preparation of said 2-substituted indazole.
    Type: Application
    Filed: April 25, 2017
    Publication date: May 16, 2019
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias THALER, Johannes PLATZEK, Nicolas GUIMOND
  • POLYMORPHIC FORM OF N-{6-(2-HYDROXYPROPAN-2-YL)-2-[2-(METHYLSULPHONYL)ETHYL]-2H-INDAZOL-5-YL}-6-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE
    Publication number: 20190112270
    Abstract: The present invention relates to crystalline forms of N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide, to processes for their preparation, to pharmaceutical compositions comprising them and to their use in the control of disorders.
    Type: Application
    Filed: April 25, 2017
    Publication date: April 18, 2019
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias THALER, Johannes PLATZEK, Nicolas GUIMOND
  • SYNTHESIS OF INDAZOLES
    Publication number: 20190106407
    Abstract: The present invention relates to a novel method of preparing a 2-substituted indazole of structure: (I), to intermediate compounds, and to the use of intermediate compounds for the preparation of said 2-substituted indazole.
    Type: Application
    Filed: April 25, 2017
    Publication date: April 11, 2019
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Tobias THALER, Johannes PLATZEK, Nicolas GUIMOND
  • Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents
    Patent number: 10189788
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Grant
    Filed: September 7, 2015
    Date of Patent: January 29, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Beck, Tobias Thaler, Raimund Kast, Daniel Meibom, Mark Meininghaus, Carsten Terjung, Martina Delbeck, Klemens Lustig, Uwe Muenster, Britta Olenik
  • SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20190002409
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Hartmut BECK, Tobias THALER, Raimund KAST, Daniel MEIBOM, Mark MEININGHAUS, Carsten TERJUNG, Martina DELBECK, Klemens LUSTIG, Uwe MUENSTER, Britta OLENIK
  • Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof
    Patent number: 10117864
    Abstract: The present application relates to novel substituted N-bicyclo-2-arylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: November 6, 2018
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Beck, Tobias Thaler, Raimund Kast, Mark Meininghaus, Carsten Terjung, Uwe Muenster, Britta Olenik
  • SUBSTITUTED N-BICYCLO-2-ARYL-QUINOLIN-4-CARBOXAMIDES AND USE THEREOF
    Publication number: 20180036300
    Abstract: The present application relates to novel substituted N-bicyclo-2-arylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.
    Type: Application
    Filed: March 15, 2016
    Publication date: February 8, 2018
    Inventors: Hartmut BECK, Tobias THALER, Raimund KAST, Mark MEININGHAUS, Carsten TERJUNG, Uwe MUENSTER, Britta OLENIK
  • SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20170260140
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Application
    Filed: September 7, 2015
    Publication date: September 14, 2017
    Applicant: Bayer Pharma Aktiengesekkschaft
    Inventors: Hartmut BECK, Tobias THALER, Raimund KAST, Daniel MEIBOM, Mark MEININGHAUS, Carsten TERJUNG, Martina DELBECK, Klemens LUSTIG, Uwe MUENSTER, Britta OLENIK