Abstract: A system for medical navigation includes an echo-endoscope configured to acquire a real-time ultrasound signal and/or a video signal; a tracking system or device configured to track a distal tip of the echo-endoscope in space; a user interface and a display; computing and storing system containing pre-operative radiologic data of a patient; wherein the computing and storing system is configured to perform a registration between real-time intra-operative data and the pre-operative radiologic data and the display is configured to provide to the user a navigation view integrating real-time intra-operative data view within the pre-operative radiologic data based on said registration.