Abstract: An injector for use with a primary package. The injector comprises distal and proximal housing components in telescopic engagement, a rod configured for axial movement with the distal housing part, and a mechanism for releasably fixing the rod to a plunger to allow trained axial movement of the rod and the plunger during telescoping together of the distal and proximal housing components over a first distance whilst allowing relative axial movement of the rod and the plunger during telescoping together of the distal and proximal housing components over a second, subsequent distance. The mechanism comprises two or more flexible fingers on one of the rod and the plunger and cooperating features on the other of the rod and the plunger, and a locking component axially moveable during telescoping between a locking position in which it substantially surrounds the flexible fingers and a release position in which it is axially spaced from the locking fingers.

Abstract: An auto-injector (100) for use with a primed safety syringe (200). The auto-injector comprises: a first detector (312) configured, after activation of the auto-injector, to detect movement of a plunger (206, 222) of the safety syringe to a point on a delivery stroke thereof that is indicative of full dose delivery of a substance from the safety syringe.

Abstract: A medicament packaging assembly for installation in a medicament delivery device is disclosed. The packaging assembly comprises a cartridge having a medicament chamber, a sealing element for sealing a distal end of the medicament chamber, a sealing element release member, a cannula and a removable cap member. The assembly is switchable from a starting configuration in which the release member is spaced from the sealing element to an activated configuration in which the release member cooperates with the sealing element to connect the medicament chamber to the cannula. The packaging assembly further comprises a first chamber defined in part by the cap member and arranged for receiving the cannula such that at least a distal end of the cannula is sealed in the first chamber when the cap member is in place, and a second chamber defined in part by the sealing element and arranged for receiving the release member.

Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.

Abstract: A medicament delivery device is disclosed, comprising a cartridge assembly that comprises a cartridge having a medicament chamber for containing a medicament, a sealing element for sealing a distal end of the medicament chamber and a coupling element attached to the cartridge. The device also includes a sealing element release member, a cannula for delivery of the medicament, and a removable cap. The device is switchable from a starting configuration in which the release member is spaced from the sealing element to an activated configuration in which the release member cooperates with the sealing element to connect the medicament chamber to the cannula. A proximal end of the release member is sealed in a release member chamber defined in part by, the sealing element and in part by the coupling element.

Abstract: A medicament delivery device (100) for delivery of medicament from a cartridge (10) into an injection site, through a cannula (134). The cartridge has a medicament chamber (14) with an outlet (15), and a sealing element (16) for closing the outlet (15). The device has a housing (102) for receiving the cartridge (10), and a drive mechanism (200) to expel the medicament from the device upon activation of the drive mechanism (200). The device has a connection arrangement (199) comprising a hub (166) and spring means (184) for driving relative movement between the hub (166) and the cartridge (10) upon operation of an operating member (190). The operating member switches the connection arrangement (199) from an unconnected configuration to a connected configuration, in which the hub (166) cooperates with the cartridge (10) to open the outlet (15). When connected, fluid may flow between the chamber (14) and the cannula (134).

Abstract: Aspects of the present invention relate to a test device comprising a housing configured to receive a test component, an inlet, integral with the housing, configured to receive body fluid; and a reservoir in fluid communication with the inlet and the test component. The inlet may be integral with the housing. Optionally the reservoir may comprise a recess in the upper wall of the housing and being in fluid communication with the inlet and the test component. Alternatively, the housing may comprise a projection from an upper wall of the housing extending into a cavity formed by the housing such that it contacts the test component to direct fluid from the reservoir along at least a part of the test component.

Abstract: Aspects of the present invention relate to an injection device configured to receive a medicament container. The injection device comprises movable means, such that before injection an information code is not visible and such that during or after injection the movable means moves to allow the code to be visible.

Abstract: A container (200) for containing a coupling medium for transdermal delivery of a medicament and a transducer unit (100) for use with the container (200) are disclosed. The transducer unit (100) has a transducer (108) with an output face (110), and the container comprises a chamber (214) for receiving the coupling medium and a contact surface (212) for contacting the output face (110) of the transducer (108). The container (200) is attachable to the transducer unit (100) and is arranged such that, upon attachment of the container (200) to the transducer unit (100), an acoustic coupling for ultrasound transmission is formed between the output face (110) of the transducer (108) and the contact surface (212).

Abstract: A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.

Abstract: A needle assembly is disclosed, for use with an injection device. The needle assembly comprises a needle hub (20) having a needle (22) and a needle shield (40) arranged for relative axial movement with respect to the needle hub, between a retracted position in which the tip of the needle projects beyond a forward end of the shield and an extended position in which the tip of the needle does not project beyond the forward end of the shield. The needle shield (40) is axially biased towards the extended position. The needle shield (40) is further arranged to be torsionally biased for relative rotational movement with respect to the needle hub (20).

Abstract: An injection device for delivering a dose from a cartridge or syringe. The injection device comprises a housing, a drive shaft, a drive spring for urging the drive shaft to rotate relative to the housing, and a plunger coupled to the drive shaft such that rotation of the drive shaft relative to the housing causes the plunger to move axially relative to the housing. The device further comprises a dose setting member moveable relative to the drive member between a first position in which the dose setting member is rotatable relative to the housing for setting a dose and a second position in which the dose setting member is rotationally fixed relative to the housing for delivering a dose, and a stop member.

Abstract: A medicament delivery device (100) for delivery of medicament from a container (12) into an injection site through a cannula (16). The device comprises a chassis (106), a drive mechanism (400) for driving a piston member (22) along a container axis (A) to expel the medicament through the cannula (16), and a carriage (200) for retaining the container (12), the cannula (16) and the drive mechanism (400). An insertion mechanism (70, 120, 130, 504) is provided for moving the carriage (200) in an insertion direction (H) relative to the chassis (106), and a cannula bending mechanism (300) is provided for bending the cannula (16) about a bending axis (B) to substantially align at least an end part of the cannula (16) with the insertion direction (H) prior to movement of the carriage (200) in the insertion direction (H).

Abstract: Pen-type lancing device of the re-usable type wherein a lancet body having a needle/tip is inserted; standard spring type actuator (urging member); skin touching forward face having a textured surface for pain relieve; sleeve having internal stop(s) so that the lancet does not overshoot. Also a pen-type lancing device of the re-usable type wherein a lancet body having a needle/tip is inserted; elastomer type urging member for driving the lancet; triggering means (denoted “actuating means”). Further a pen-type lancing device of the reusable type wherein a lancet body having a needle/tip is inserted; standard spring type actuator (urging member) for driving the lancet; alignment splines and cooperating alignment portion(s) for guiding the lancet movement. Even further a method of assembling a blood sampling device in which it does not matter what rotational orientation the components are assembled in.

Abstract: A device (200) for mixing first and second substances. The device comprises a first container (100) for storage of the first substance and a second container (150) received in the first container (100) and for storage of the second substance. An outlet (112) is disposed at the distal end of the first container (100). Valve means (180) are provided for closing a distal end of the second container (150) and a proximal end of the first container (100). A stopper means (166) closes a proximal end of the second chamber (152) and is movable with respect to the second container (150). An operating mechanism drives relative movement between the first and second containers for causing displacement of the second substance into the first chamber (102) through the valve means (180) when the outlet (112) is closed, for mixing the first and second substances in a mixing stroke of the device.

Abstract: A medicament delivery device (100) for the delivery of medicament from a container (12) through a cannula (16). The device comprises a chassis (300), a carriage (200), and an insertion spring (70) for biasing the carriage (200) for movement in an insertion direction with respect to the chassis (300) from a starting position in which the cannula (16) is shrouded to an insertion position in which the cannula (16) is extended. A drive mechanism (400) is provided for driving the container's stopper (22) to expel medicament. The drive mechanism (400) is carried by the carriage (200) and comprises a movable drive member (404), a drive means (40) for applying a driving force to the drive member (404), and force transmission means (406) for transmitting the driving force to the stopper (22). The drive means (40) is arranged around or alongside at least part of the force transmission means (406).

Abstract: A device (200) for mixing first and second substances. The device comprises a first container (100) for storage of the first substance and a second container (150) received in the first container (100) and for storage of the second substance. An outlet (112) is disposed at the distal end of the first container (100). Valve means (180) are provided for closing a distal end of the second container (150) and a proximal end of the first container (100). A stopper means (166) closes a proximal end of the second chamber (152) and is movable with respect to the second container (150). An operating mechanism drives relative movement between the first and second containers for causing displacement of the second substance into the first chamber (102) through the valve means (180) when the outlet (112) is closed, for mixing the first and second substances in a mixing stroke of the device.