Patents by Inventor Toby E. Claus

Toby E. Claus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for cloning and producing the Msel restriction endonuclease
    Patent number: 6846658
    Abstract: A method for cloning restriction-modification system is provided whereby the target modification methylase is produced and confers full protection during all growth phases in which the cognate restriction enzyme is present. The method is employed in the cloning of the MseI restriction-modification system.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: January 25, 2005
    Assignee: New England Biolabs, Inc.
    Inventors: Romualdas Vaisvila, Richard D. Morgan, Rebecca B. Kucera, Toby E. Claus, Elisabeth A. Raleigh
  • Isolated DNA encoding the NotI restriction endonuclease and related methods for producing the same
    Patent number: 5371006
    Abstract: The present invention is directed to a method for cloning and producing the NotI restriction endonuclease by 1) introducing the restriction endonuclease gene from Nocardia otitidis-caviarum into a host whereby the restriction gene is expressed; 2) fermenting the host which contains the plasmid encoding and expressing the NotI restriction endonuclease activity, and 3) purifying the NotI restriction endonuclease from the fermented host which contains the plasmid encoding and expressing the NotI restriction endonuclease activity.
    Type: Grant
    Filed: January 11, 1993
    Date of Patent: December 6, 1994
    Assignee: New England Biolabs, Inc.
    Inventors: Richard D. Morgan, Jack S. Benner, Toby E. Claus