Patents by Inventor Toby Jackson

Toby Jackson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenyl-sulfamates as aromatase inhibitors
    Patent number: 8470860
    Abstract: There is provided a compound of Formula I wherein X, Y and Z are each independently of each other an optional linker group; R1 is a ring system; R2 is selected from hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2) and halogens; R3 and R4 are independently selected from H and hydrocarbyl, ring A and B are independently optionally further substituted.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: June 25, 2013
    Assignee: Sterix Limited
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Christian Bubert, Atul Purohit, Michael John Reed, Barry Victor Lloyd Potter
  • Compound
    Patent number: 8093279
    Abstract: There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and —Y—R8; wherein each R8 is independently selected from —OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2), H-bond acceptors, and halogens; wherein at least one of R3, R4, R5, R6 and R7 is —Y—R8 wherein R8 is selected from substituted and unsubstituted heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further substituted; wherein R9 is selected from H, —OH and —OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is —Y—R8; OR (b) R9 is —OSO2NR1R2 or —OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is —Y—R8.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: January 10, 2012
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Atul Purohit, Michael John Reed, Gillian Reed, legal representative, Barry Victor Lloyd Potter
  • 1,2,4-triazol-1-yl bisphenyl derivatives for use in the treatment of endocrine-dependent tumors
    Patent number: 8022224
    Abstract: There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and —Y—R8; wherein each R8 is independently selected from —OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2), H-bond acceptors, and halogens; wherein at least one of R3, R4, R5, R6 and R7 is —Y—R8 wherein R8 is selected from substituted and unsubstituted heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further substituted; wherein R9 is selected from H, —OH and —OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is —Y—R8; OR (b) R9 is —OSO2NR1R2 or —OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is —Y—R8. These compounds inhibit steroid sulphatase and aromatase activity and are useful in the treatment of endocrine-dependent tumors.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: September 20, 2011
    Assignee: Sterix Limited
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Atul Purohit, Michael John Reed, Barry Victor Lloyd Potter
  • PHENYL-SULFAMATES AS AROMATASE INHIBITORS
    Publication number: 20110021586
    Abstract: There is provided a compound of Formula I wherein X, Y and Z are each independently of each other an optional linker group; R1 is a ring system; R2 is selected from hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2) and halogens; R3 and R4 are independently selected from H and hydrocarbyl, ring A and B are independently optionally further substituted.
    Type: Application
    Filed: July 22, 2010
    Publication date: January 27, 2011
    Applicant: Sterix, Limited
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Christian Bubert, Atul Purohit, Michael John Reed, Barry Victory Lloyd Potter
  • Phenyl-sulfamates as aromatase inhibitors
    Patent number: 7763642
    Abstract: There is provided a compound of Formula I wherein X, Y and Z are each independently of each other an optional linker group; R1 is a ring system; R2 is selected from hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2) and halogens; R3 and R4 are independently selected from H and hydrocarbyl, ring A and B are independently optionally further substituted.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: July 27, 2010
    Assignee: Sterix Ltd.
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Christian Bubert, Atul Purohit, Michael John Reed, Barry Victory Lloyd Potter
  • COMPOUND
    Publication number: 20100173963
    Abstract: There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and —Y—R8; wherein each R8 is independently selected from —OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2), H-bond acceptors, and halogens; wherein at least one of R3, R4, R5, R6 and R7 is —Y—R8 wherein R8 is selected from substituted and unsubstituted heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further substituted; wherein R9 is selected from H, —OH and —OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is —Y—R8; OR (b) R9 is —OSO2NR1R2 or —OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is —Y—R8.
    Type: Application
    Filed: September 8, 2009
    Publication date: July 8, 2010
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Atul Purohit, Michael John Reed, Barry Victor Lloyd Potter, Gillin Reed
  • 1,2,4-TRIAZOL-1-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMORS
    Publication number: 20080319037
    Abstract: There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and —Y—R8; wherein each R8 is independently selected from —OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2), H-bond acceptors, and halogens; wherein at least one of R3, R4, R5, R6 and R7 is —Y—R8 wherein R8 is selected from substituted and unsubstituted heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further substituted; wherein R9 is selected from H, —OH and —OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is —Y—R8; OR (b) R9 is —OSO2NR1R2 or —OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is —Y—R8. These compounds inhibit steroid sulphatase and aromatase activity and are useful in the treatment of endocrine-dependent tumors.
    Type: Application
    Filed: June 13, 2008
    Publication date: December 25, 2008
    Inventors: Lok Wai Lawrence Woo, Toby Jackson, Atul Purohit, Michael John Reed, Barry Victor Lloyd Potter
  • Phenyl-sulfamates as aromatase inhibitors
    Publication number: 20070117855
    Abstract: There is provided a compound of Formula I wherein X, Y and Z are each independently of each other an optional linker group; R1 is a ring system; R2 is selected from hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2) and halogens; R3 and R4 are independently selected from H and hydrocarbyl, ring A and B are independently optionally further substituted.
    Type: Application
    Filed: December 4, 2006
    Publication date: May 24, 2007
    Inventors: Lok Lawrence Woo, Toby Jackson, Christian Bubert, Atul Purohit, Michael Reed, Barry Victory Potter