Patents by Inventor Toby M. Freyman

Toby M. Freyman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microencapsulated compositions for endoluminal tissue engineering
    Patent number: 8518682
    Abstract: A tissue engineering composition adapted for application to an interior surface of a body lumen of a patient. The composition comprises (a) a carrier medium that is adapted to flow and to stably adhere the composition to the body lumen and (b) microcapsules, which are dispersed within the carrier medium and which contain one or more living cells encapsulated within a coating that includes a biodegradable polymer. The composition promotes growth of the cells on the lumen surface subsequent to application of the composition to the lumen.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: August 27, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Toby M. Freyman, Joseph A. Levendusky
  • MICROENCAPSULATED COMPOSITIONS FOR ENDOLUMINAL TISSUE ENGINEERING
    Publication number: 20110189240
    Abstract: A tissue engineering composition adapted for application to an interior surface of a body lumen of a patient. The composition comprises (a) a carrier medium that is adapted to flow and to stably adhere the composition to the body lumen and (b) microcapsules, which are dispersed within the carrier medium and which contain one or more living cells encapsulated within a coating that includes a biodegradable polymer. The composition promotes growth of the cells on the lumen surface subsequent to application of the composition to the lumen.
    Type: Application
    Filed: December 13, 2010
    Publication date: August 4, 2011
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Toby M. Freyman, Joseph A. Levendusky
  • Microencapsulated compositions for endoluminal tissue engineering
    Patent number: 7851189
    Abstract: A tissue engineering composition adapted for application to an interior surface of a body lumen of a patient. The composition comprises (a) a carrier medium that is adapted to flow and to stably adhere the composition to the body lumen and (b) microcapsules, which are dispersed within the carrier medium and which contain one or more living cells encapsulated within a coating that includes a biodegradable polymer. The composition promotes growth of the cells on the lumen surface subsequent to application of the composition to the lumen.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: December 14, 2010
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Toby M. Freyman, Joseph A. Levendusky
  • METHODS FOR REPAIR AND REGENERATION OF BONE MARROW
    Publication number: 20090180965
    Abstract: The invention is directed to a method for treating a tissue or organ in a subject by directly administering an effective amount of an exogenous, decellularized extracellular matrix or a mixture of extracellular matrix and mesenchymal stem cells into the intended site of activity, such as bone marrow cavity. In one embodiment, the invention provides methods of treating bone marrow to increase the number of circulating progenitor and stem cells. In some other embodiments of the invention, the decellularized extracellular matrix to be directly administered is configured to be a time released therapeutic.
    Type: Application
    Filed: January 2, 2009
    Publication date: July 16, 2009
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Toby M. Freyman, Wendy Naimark, Maria Palasis