Patents by Inventor Toby Passioura

Toby Passioura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic Peptide
    Publication number: 20210395310
    Abstract: The purpose of the present invention is to provide a cyclic peptide having any unit structure selected from the structures represented by the following formula (1): —X1—X2—X3—X4—X5—??(1) (in the formula (1), X1 is I, V or L, or an N-alkylamino acid thereof, X2 is S or T, or an N-alkylamino acid thereof, X3 is K or an N-alkylamino acid thereof, X4 is W or an N-alkylamino acid thereof, and X5 is W, Y, or H, or K or an N-alkylamino acid thereof), or a pharmaceutically acceptable salt of the cyclic peptide.
    Type: Application
    Filed: September 6, 2019
    Publication date: December 23, 2021
    Inventors: Hiroaki Suga, Toby Passioura, Kenichiro Ito, Kunio Matsumoto, Katsuya Sakai, Hiroki Sato
  • NTCP Inhibitor
    Publication number: 20210061859
    Abstract: The present invention provides a sodium taurocholate cotransporting polypeptide (NTCP) inhibitor comprising a cyclic peptide having a Xw1-W-Xw2-W structure, wherein Xw1 and Xw2 are each independently T, S, I, L, or V, or a N-alkylamino acid thereof, or having a P-Xp1-Xp2-H structure, wherein Xp1 is any amino acid, and Xp2 is I, L, or V, or a N-alkylamino acid thereof, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 11, 2019
    Publication date: March 4, 2021
    Inventors: Hiroaki Suga, Toby Passioura, Takaji Wakita, Koichi Watashi
  • Multitargeting interfering RNAs having two active strands and methods for their design and use
    Patent number: 8097715
    Abstract: Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. The multitargeting interfering RNA molecules have two strands that target multiple target sites on one or more pre-selected RNA molecules. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: January 17, 2012
    Assignee: Johnson & Johnson Research PTY Limited
    Inventors: Laurent Pierre Rivory, Michael Poidinger, Donald John Birkett, Gregory Martin Arndt, Toby Passioura
  • SUPPRESSION OF VIRUSES INVOLVED IN RESPIRATORY INFECTION OR DISEASE
    Publication number: 20100286238
    Abstract: The present invention concerns methods and reagents useful in decreasing the level of or severity of respiratory infection or disease due to paramyxoviruses, such as RSV or HPIV, or coronavirus infection. Particularly, the invention relates to modulating gene expression using a multitargeting interfering RNA molecules that target multiple target sites on one or more pre-selected RNA molecules.
    Type: Application
    Filed: May 14, 2008
    Publication date: November 11, 2010
    Inventors: Laurent Pierre Rivory, Michael Poidinger, Donald John Birkett, Gregory Martin Arndt, Toby Passioura
  • Multitargeting Interfering RNAs And Methods Of Their Use And Design
    Publication number: 20090239816
    Abstract: Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation.
    Type: Application
    Filed: May 21, 2008
    Publication date: September 24, 2009
    Applicant: Johnson & Johnson Research PTY. Limited
    Inventors: Laurent Pierre Rivory, Michael Poidinger, Donald John Birkett, Gregory Martin Arndt, Toby Passioura
  • Multitargeting Interfering RNAs Having Two Active Strands And Methods For Their Design And Use
    Publication number: 20090192103
    Abstract: Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. The multitargeting interfering RNA molecules have two strands that target multiple target sites on one or more pre-selected RNA molecules. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation.
    Type: Application
    Filed: May 21, 2008
    Publication date: July 30, 2009
    Applicant: Johnson & Johnson Research PTY. Limited
    Inventors: Laurent Pierre RIVORY, Michael Poidinger, Donald John Birkett, Gregory Martin Arndt, Toby Passioura
  • Multitargeting interfering RNAs having two active strands and methods for their design and use
    Publication number: 20070269815
    Abstract: Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. The multitargeting interfering RNA molecules have two strands that target multiple target sites on one or more pre-selected RNA molecules. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation.
    Type: Application
    Filed: November 21, 2006
    Publication date: November 22, 2007
    Inventors: Laurent Rivory, Michael Poidinger, Donald Birkett, Gregory Arndt, Toby Passioura