Patents by Inventor Toby Richardson

Toby Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dehalogenases, Nucleic Acids Encoding Them and Methods for Making and Using Them
    Publication number: 20100112666
    Abstract: The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: January 7, 2010
    Publication date: May 6, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Jay M. Short, Toby Richardson, Dan E. Robertson, Kevin A. Gray
  • Enzymes having dehalogenase activity and methods of use thereof
    Patent number: 7671189
    Abstract: The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: March 2, 2010
    Assignee: Verenium Corporation
    Inventors: Jay M. Short, Toby Richardson, Dan E. Robertson, Kevin A. Gray
  • Enzymes Having Alpha Amylase Activity and Methods of Making and Using Them
    Publication number: 20100047392
    Abstract: The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures.
    Type: Application
    Filed: September 25, 2009
    Publication date: February 25, 2010
    Applicant: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Enzymes having alpha amylase activity and methods of making and using them
    Patent number: 7666633
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases, and methods of making and using them. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: February 23, 2010
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric J. Mathur
  • Amylases, nucleic acids encoding them and methods for making and using them
    Patent number: 7659102
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into 10 sugars.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: February 9, 2010
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl A. Miller, Martin Kazaoka, Eric J. Mathur, Jay M. Short
  • Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
    Patent number: 7582455
    Abstract: Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: September 1, 2009
    Assignee: Cargill, Incorporated
    Inventors: Brian J. Brazeau, Ellen Burke, Mervyn DeSouza, Steven J. Gort, Paula M. Hicks, Sherry R. Kollmann, Peter Luginbuhl, Sara C. McFarlan, Toby Richardson, Fernando A. Sanchez-Riera, Christopher Solheid, David Weiner, Lishan Zhao
  • Amylases, nucleic acids encoding them and methods for making and using them
    Patent number: 7560126
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: July 14, 2009
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska, Nelson R. Barton, Eileen O'Donoghue, Eric J. Mathur, Jay M. Short
  • Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them
    Publication number: 20090038023
    Abstract: This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.
    Type: Application
    Filed: March 10, 2006
    Publication date: February 5, 2009
    Applicant: Verenium Corporation
    Inventors: David P. Weiner, Alexander Varvak, Toby Richardson, Mircea Podar, Ellen Burke, Shaun Healey
  • Enzymes having alpha amylase activity and methods of use thereof
    Patent number: 7407677
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: August 5, 2008
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Nanoarchaeum genome, Nanoarchaeum polypeptides and nucleic acids encoding them and methods for making and using them
    Publication number: 20080168572
    Abstract: The invention provides a genome of the hyperthermophile Nanoarchaeum equitans, polypeptides, including enzymes, structural protein and binding proteins, derived from this genome, polynucleotides encoding these polypeptides, methods of making and using these polynucleotides and polypeptides. The invention also provides isolated hyperthermophile Nanoarchaeum equitans.
    Type: Application
    Filed: May 1, 2003
    Publication date: July 10, 2008
    Applicant: Diversa Corporation
    Inventors: Karl O. Stetter, Elizabeth Waters, Keith Kretz, Mircea Podar, Toby Richardson, Michiel Noordewier
  • NUCLEIC ACIDS ENCODING POLYPEPTIDES HAVING AMYLASE ACTIVITY AND METHODS OF MAKING AND USING THEM
    Publication number: 20080047037
    Abstract: The invention relates to nucleic acids encoding polypeptides having amylase activity, and methods for making and using them. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides encoded by the nucleic acids of this invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: February 21, 2008
    Applicant: Diversa Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • POLYPEPTIDES HAVING AMYLASE ACTIVITY AND METHODS OF MAKING AND USING THEM
    Publication number: 20080032378
    Abstract: This invention relates generally to polypeptides and peptides having an amylase activity, e.g., enzymes, polynucleotides encoding the enzymes, the use of such polypeptides and peptides. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides having amylase activity of the invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: February 7, 2008
    Applicant: Diversa Corporation
    Inventors: Walter CALLEN, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • Enzymes having alpha amylase activity and methods of use thereof
    Patent number: 7323336
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: January 29, 2008
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric J. Mathur
  • Aldolases, nucleic acids encoding them and methods for making and using them
    Publication number: 20080020435
    Abstract: This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In some embodiments, the invention is directed to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides in accordance with the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.
    Type: Application
    Filed: March 7, 2007
    Publication date: January 24, 2008
    Applicant: Cargill, Incorporated
    Inventors: Ellen Burke, Steven Gort, Paula Hicks, Peter Luginbuhl, Sara McFarlan, Toby Richardson, Christopher Solheid, David Weiner, Lishan Zhao
  • VACCINES
    Publication number: 20070286871
    Abstract: The present invention relates to compositions for inducing immune responses, including an antigen and a promiscuous T-cell epitope. Also provided are methods of inducing immune responses in hosts, comprising administering compositions comprising antigens and promiscuous T-cell epitopes to the host.
    Type: Application
    Filed: April 3, 2007
    Publication date: December 13, 2007
    Applicant: Diversa Corporation
    Inventors: Leslie Hickle, Abraham Anderson, Robert Brown, Paul Budworth, Gordana Djordjevic, Scott Kroken, Peter Luginbuhl, Toby Richardson, Genevieve Hansen
  • P450 ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS OF MAKING AND USING THEM
    Publication number: 20070231820
    Abstract: The invention is directed to polypeptides having P450 activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using these polynucleotides and polypeptides. The P450 enzymes can be used to catalyze the hydrolysis of epoxides and arene oxides to their corresponding diols.
    Type: Application
    Filed: March 16, 2007
    Publication date: October 4, 2007
    Applicant: Diversa Corporation
    Inventors: David Weiner, Mark Burk, Tim Hitchman, Catherine Pujol, Toby Richardson, Jay Short
  • Enzymes having alpha amylase activity and methods of use thereof
    Patent number: 7273740
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: September 25, 2007
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric Mathur
  • METHODS FOR USING POLYPEPTIDES HAVING AMYLASE ACTIVITY AND NUCLEIC ACIDS ENCODING THEM
    Publication number: 20070161099
    Abstract: The invention relates to uses of polypeptides having amylase activity, nucleic acids encoding them, and methods for making and using them. For example, in one aspect, the invention provides methods for making alcohol using polypeptides of the invention. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, for hydrolyzing a starch, comprising use of polypeptides of the invention, or polypeptides encoded by the nucleic acids of this invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: July 12, 2007
    Applicant: Diversa Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • Amylases, nucleic acids encoding them and methods for making and using them
    Publication number: 20070157329
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating.
    Type: Application
    Filed: March 8, 2004
    Publication date: July 5, 2007
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Kevin Gray, Janne Kerovuo, Malgorzata Slupska, Nelson Barton, Eileen O'Donoghue, Carl Miller
  • P450 enzymes, nucleic acids encoding them and methods of making and using them
    Patent number: 7232672
    Abstract: The invention is directed to polypeptides having P450 activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using these polynucleotides and polypeptides. The P450 enzymes can be used to catalyze the hydrolysis of epoxides and arene oxides to their corresponding diols.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: June 19, 2007
    Assignee: Diversa Corporation
    Inventors: David Weiner, Mark J. Burk, Tim Hitchman, Catherine Pujol, Toby Richardson, Jay M. Short