Patents by Inventor Toby Richardson

Toby Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7785855
    Abstract: The invention relates to nucleic acids encoding polypeptides having amylase activity, and methods for making and using them. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides encoded by the nucleic acids of this invention.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: August 31, 2010
    Assignee: Syngenta Participations AG
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Patent number: 7781201
    Abstract: This invention relates generally to polypeptides and peptides having an amylase activity, e.g., enzymes, polynucleotides encoding the enzymes, the use of such polypeptides and peptides. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides having amylase activity of the invention.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: August 24, 2010
    Assignee: Syngenta Participations AG
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Publication number: 20100209995
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
    Type: Application
    Filed: February 1, 2010
    Publication date: August 19, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Eric Mathur, Jay Short
  • Publication number: 20100189706
    Abstract: The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a ?-xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention.
    Type: Application
    Filed: January 30, 2008
    Publication date: July 29, 2010
    Inventors: Cathy Chang, Justin T. Stege, Nahla Aboushadi, Gordana Djordjevic, Ellen Burke, Peter Luginbuhl, Mark Dycaico, Toby Richardson, John Poland, Ying Hefner, Stacy Marie Miles
  • Patent number: 7759093
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: July 20, 2010
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Kevin Gray, Janne S. Kerovuo, Malgorzata Slupska, Nelson Barton, Eileen O'Donoghue, Carl Miller
  • Publication number: 20100112666
    Abstract: The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: January 7, 2010
    Publication date: May 6, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Jay M. Short, Toby Richardson, Dan E. Robertson, Kevin A. Gray
  • Patent number: 7671189
    Abstract: The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: March 2, 2010
    Assignee: Verenium Corporation
    Inventors: Jay M. Short, Toby Richardson, Dan E. Robertson, Kevin A. Gray
  • Publication number: 20100047392
    Abstract: The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures.
    Type: Application
    Filed: September 25, 2009
    Publication date: February 25, 2010
    Applicant: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Patent number: 7666633
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases, and methods of making and using them. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: February 23, 2010
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric J. Mathur
  • Patent number: 7659102
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into 10 sugars.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: February 9, 2010
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl A. Miller, Martin Kazaoka, Eric J. Mathur, Jay M. Short
  • Patent number: 7582455
    Abstract: Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: September 1, 2009
    Assignee: Cargill, Incorporated
    Inventors: Brian J. Brazeau, Ellen Burke, Mervyn DeSouza, Steven J. Gort, Paula M. Hicks, Sherry R. Kollmann, Peter Luginbuhl, Sara C. McFarlan, Toby Richardson, Fernando A. Sanchez-Riera, Christopher Solheid, David Weiner, Lishan Zhao
  • Patent number: 7560126
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: July 14, 2009
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska, Nelson R. Barton, Eileen O'Donoghue, Eric J. Mathur, Jay M. Short
  • Publication number: 20090038023
    Abstract: This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.
    Type: Application
    Filed: March 10, 2006
    Publication date: February 5, 2009
    Applicant: Verenium Corporation
    Inventors: David P. Weiner, Alexander Varvak, Toby Richardson, Mircea Podar, Ellen Burke, Shaun Healey
  • Patent number: 7407677
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: August 5, 2008
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska
  • Publication number: 20080168572
    Abstract: The invention provides a genome of the hyperthermophile Nanoarchaeum equitans, polypeptides, including enzymes, structural protein and binding proteins, derived from this genome, polynucleotides encoding these polypeptides, methods of making and using these polynucleotides and polypeptides. The invention also provides isolated hyperthermophile Nanoarchaeum equitans.
    Type: Application
    Filed: May 1, 2003
    Publication date: July 10, 2008
    Applicant: Diversa Corporation
    Inventors: Karl O. Stetter, Elizabeth Waters, Keith Kretz, Mircea Podar, Toby Richardson, Michiel Noordewier
  • Publication number: 20080047037
    Abstract: The invention relates to nucleic acids encoding polypeptides having amylase activity, and methods for making and using them. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides encoded by the nucleic acids of this invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: February 21, 2008
    Applicant: Diversa Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • Publication number: 20080032378
    Abstract: This invention relates generally to polypeptides and peptides having an amylase activity, e.g., enzymes, polynucleotides encoding the enzymes, the use of such polypeptides and peptides. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides having amylase activity of the invention.
    Type: Application
    Filed: January 9, 2007
    Publication date: February 7, 2008
    Applicant: Diversa Corporation
    Inventors: Walter CALLEN, Toby Richardson, Gerhard Frey, Jay Short, Eric Mathur, Kevin Gray, Janne Kerovuo, Malgorzata Slupska
  • Patent number: 7323336
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: January 29, 2008
    Assignee: Verenium Corporation
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Carl Miller, Martin Kazaoka, Jay M. Short, Eric J. Mathur
  • Publication number: 20080020435
    Abstract: This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In some embodiments, the invention is directed to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides in accordance with the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.
    Type: Application
    Filed: March 7, 2007
    Publication date: January 24, 2008
    Applicant: Cargill, Incorporated
    Inventors: Ellen Burke, Steven Gort, Paula Hicks, Peter Luginbuhl, Sara McFarlan, Toby Richardson, Christopher Solheid, David Weiner, Lishan Zhao
  • Publication number: 20070286871
    Abstract: The present invention relates to compositions for inducing immune responses, including an antigen and a promiscuous T-cell epitope. Also provided are methods of inducing immune responses in hosts, comprising administering compositions comprising antigens and promiscuous T-cell epitopes to the host.
    Type: Application
    Filed: April 3, 2007
    Publication date: December 13, 2007
    Applicant: Diversa Corporation
    Inventors: Leslie Hickle, Abraham Anderson, Robert Brown, Paul Budworth, Gordana Djordjevic, Scott Kroken, Peter Luginbuhl, Toby Richardson, Genevieve Hansen