Abstract: Methods and systems are provided for generating regional digital subtraction angiography (DSA) images and roadmap images with landmarks. In one embodiment, a method comprises generating a mask from a set of mask images of an anatomy of a subject, and generating a masked image by applying the mask to acquired image data of the anatomy of the subject, including weighting the mask differently inside a region of interest (ROI) of the image than outside the ROI, the weighting inside ROI independent of the weighting outside the ROI. In this way, a user may be able to adjust a relative magnitude of subtraction inside and outside the ROI, and thus be able to visualize both vasculature and landmarks within the same image frame.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: A hanging system is disclosed. The hanging system is especially adapted to couple with travel bags of various sizes for holding garments and accessories in place when traveling or commuting. A second embodiment includes a hangar accessory which allows the hanging system to be mounted from a standard hanging rod.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: Computer program products, methods, systems, apparatus, and computing entities for tracking an item delivery are provided. In one embodiment, an item is associated with a vehicle (e.g., manned or unmanned terrestrial vehicle, nautical vehicle, and/or aerial vehicle) by updating item data in a database. An item tracking session is then generated based on the item data. Upon the determination that session availability trigger has occurred, access to the item tracking session is provided to a user. Data representing an updated location of the delivery vehicle is then used to update the item data to indicate the current location of the item as the updated location of the vehicle.

Abstract: Computer program products, methods, systems, apparatus, and computing entities for tracking an item delivery are provided. In one embodiment, an item is associated with a vehicle (e.g., manned or unmanned terrestrial vehicle, nautical vehicle, and/or aerial vehicle) by updating item data in a database. An item tracking session is then generated based on the item data. Upon the determination that session availability trigger has occurred, access to the item tracking session is provided to a user. Data representing an updated location of the delivery vehicle is then used to update the item data to indicate the current location of the item as the updated location of the vehicle.

Abstract: Systems and methods for preparing osteoinductive synthetic bone grafts are provided in which a porous ceramic granule, which may be incorporated within a biocompatible matrix material, is loaded with an osteoinductive agent. Loading of granules is facilitated in some cases by the use of low-pH buffers and pre-treatments.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: A method of manufacturing curved composite structural elements can include fabricating a web ply in a flat curve over a removable substrate and laying up the ply on a curved web surface of a manufacturing tool. The method also can include laying up a diagonal ply with fibers oriented at +/?45° from the centerline of the web surface. The method further can include cutting a unidirectional composite tape into segments and laying up the tape segments to form a cross ply with a fiber orientation normal to the centerline of the web surface. One or both edges of the diagonal and cross plies may be folded over one or two sides of the manufacturing tool to form one or two flange surfaces. Additionally, a cap ply can be laid up on one or both flange surfaces using composite tape. The structural element layup can then be inspected and any excess composite material can be trimmed away.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Abstract: A sealing machine adapted to support a plurality of different heating/sealing/cutting mechanisms, including tubular heaters and heated cutting blades, is disclosed. The sealing machine utilizes a common interface and mounting system for all side sealers. In addition, in some embodiments, the control system within the sealing machine is adapted to monitor and control the temperature of these various mechanisms automatically so as to create proper seals.

Abstract: A method of manufacturing curved composite structural elements can include fabricating a web ply in a flat curve over a removable substrate and laying up the ply on a curved web surface of a manufacturing tool. The method also can include laying up a diagonal ply with fibers oriented at +/?45° from the centerline of the web surface. The method further can include cutting a unidirectional composite tape into segments and laying up the tape segments to form a cross ply with a fiber orientation normal to the centerline of the web surface. One or both edges of the diagonal and cross plies may be folded over one or two sides of the manufacturing tool to form one or two flange surfaces. Additionally, a cap ply can be laid up on one or both flange surfaces using composite tape. The structural element layup can then be inspected and any excess composite material can be trimmed away.

Abstract: A tubular heating element which is resistant to damage caused by foreign material is disclosed. The tubular heating element is pivotably attached to the side sealing machine at its leading (upstream) edge. The trailing (downstream) edge of the tubular heating element is moved by means of a compressible force, such as an air cylinder. In this way, the air in the cylinder pushes the tubular heating element downward into the plane of the film. However, a foreign object located on the film can overcome the force of the air cylinder, thereby lifting the tubular heating element out of the path of the film.

Abstract: A method of manufacturing curved composite structural elements can include fabricating a web ply in a flat curve over a removable substrate and laying up the ply on a curved web surface of a manufacturing tool. The method also can include laying up a diagonal ply with fibers oriented at +/?45° from the centerline of the web surface. The method further can include cutting a unidirectional composite tape into segments and laying up the tape segments to form a cross ply with a fiber orientation normal to the centerline of the web surface. One or both edges of the diagonal and cross plies may be folded over one or two sides of the manufacturing tool to form one or two flange surfaces. Additionally, a cap ply can be laid up on one or both flange surfaces using composite tape. The structural element layup can then be inspected and any excess composite material can be trimmed away.

Abstract: A thin sealing device which is resistant to damage caused by foreign material is disclosed. The thin sealing device has an internal heating element. The thin sealing device has a blunt edge, which has a radius smaller than that of the heating element. A thermocouple is placed in a cavity near this blunt edge to monitor the temperature at the point of sealing. In some embodiments, the thin sealing device is pivotably attached at its leading (upstream) edge. The trailing (downstream) edge of the thin sealing device is moved by means of a compressible force, such as an air cylinder. In this way, the air in the cylinder pushes the thin sealing device downward into the plane of the film. However, a foreign object located on the film can overcome the force of the air cylinder, thereby lifting the thin sealing device out of the path of the film.

Abstract: A sealing machine adapted to support a plurality of different heating/sealing/cutting mechanisms, including tubular heaters and heated cutting blades, is disclosed. The sealing machine utilizes a common interface and mounting system for all side sealers. In addition, in some embodiments, the control system within the sealing machine is adapted to monitor and control the temperature of these various mechanisms automatically so as to create proper seals.

Abstract: A tubular heating element which is resistant to damage caused by foreign material is disclosed. The tubular heating element is pivotably attached to the side sealing machine at its leading (upstream) edge. The trailing (downstream) edge of the tubular heating element is moved by means of a compressible force, such as an air cylinder. In this way, the air in the cylinder pushes the tubular heating element downward into the plane of the film. However, a foreign object located on the film can overcome the force of the air cylinder, thereby lifting the tubular heating element out of the path of the film.

Abstract: The method for controlling a safety system (102-108) of a vehicle (10) determines a reference velocity from a first front wheel sensor (20A) and a second front wheel speed signal from a second front wheel sensor (20B). An axle speed sensor (20C) may be used to determine an axle speed signal. A first rear speed signal and a second rear speed signal are determined from the reference velocity, a slip effect and a yaw signal. The yaw signal may be determined from a yaw rate sensor (28). Safety system (102-108) may be controlled in response to the first rear wheel speed signal and the second rear wheel speed signal.