Patents by Inventor Todd A. Ciche

Todd A. Ciche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210246464
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
    Type: Application
    Filed: April 27, 2021
    Publication date: August 12, 2021
    Applicant: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Uma R. Kesanapalli, Jennifer L. Lutke
  • Patent number: 11021715
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: June 1, 2021
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Urna R. Kesanapalli, Jennifer L. Lutke
  • Publication number: 20200370066
    Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
    Type: Application
    Filed: June 8, 2020
    Publication date: November 26, 2020
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Jason S. Milligan, James K. Roberts, Yong Yin
  • Publication number: 20200308632
    Abstract: Methods useful in detecting viable microbes in an agricultural composition are provided. Certain embodiments relate to methods in which a sample of an agricultural composition is obtained, and an amount of at least one pre-rRNA from at least one microbe is detected. The detected pre-rRNA from an agricultural sample may be compared with the amount of pre-rRNA from a control sample to determine the presence of a viable microbe.
    Type: Application
    Filed: August 29, 2018
    Publication date: October 1, 2020
    Inventors: Adil Anjem, Amy L. Caruano-Yzermans, Todd A. Ciche, Julia L. Stevens, Keith H. Turner
  • Publication number: 20200229445
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3 pesticidal proteins are also provided. Also disclosed are methods and compositions to improve the insecticidal activity of a pesticidal protein against an insect pest species.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 23, 2020
    Inventors: David J. Bowen, Catherine A Chay, Danqi Chen, Todd A. Ciche, Arlene R. Howe, Jennifer L. Lutke, Barbara E. Wiggins, Yuanji Zhang
  • Patent number: 10717989
    Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: July 21, 2020
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Jason S. Milligan, James K. Roberts, Yong Yin
  • Publication number: 20200115721
    Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention.
    Type: Application
    Filed: October 21, 2019
    Publication date: April 16, 2020
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Krishnakumar Sridharan
  • Publication number: 20200095603
    Abstract: A pesticidal protein class of PirA, PirB, and PirAB fusion proteins exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the PirA, PirB, and PirAB fusion proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran, Lepidopteran, and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the PirA, PirB, and PirAB fusion proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the PirA, PirB, and PirAB fusion proteins are also provided.
    Type: Application
    Filed: September 24, 2019
    Publication date: March 26, 2020
    Inventors: DAVID J. BOWEN, CATHERINE A. CHAY, TODD A. CICHE, ARLENE R. HOWE
  • Patent number: 10465205
    Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: November 5, 2019
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Krishnakumar Sridharan
  • Publication number: 20190055577
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
    Type: Application
    Filed: November 2, 2018
    Publication date: February 21, 2019
    Applicant: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Uma R. Kesanapalli, Jennifer L. Lutke
  • Patent number: 10155960
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: December 18, 2018
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Uma R. Kesanapalli, Jennifer L. Lutke
  • Publication number: 20180291395
    Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention.
    Type: Application
    Filed: April 3, 2018
    Publication date: October 11, 2018
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Krishnakumar Sridharan
  • Publication number: 20180208940
    Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
    Type: Application
    Filed: December 19, 2017
    Publication date: July 26, 2018
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Jason S. Milligan, James K. Roberts, Yong Yin
  • Publication number: 20170058294
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
    Type: Application
    Filed: August 25, 2016
    Publication date: March 2, 2017
    Applicant: Monsanto Technology LLC
    Inventors: David J. BOWEN, Catherine A. CHAY, Todd A. CICHE, Uma R. KESANAPALLI, Jennifer L. LUTKE
  • Patent number: 7569748
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterohabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: August 4, 2009
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Publication number: 20030207806
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Application
    Filed: October 2, 2002
    Publication date: November 6, 2003
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Patent number: 6528484
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: March 4, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Publication number: 20020147148
    Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.
    Type: Application
    Filed: February 19, 2002
    Publication date: October 10, 2002
    Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, Todd A. Ciche, James K. Petell, James A. Strickland, Gregory L. Orr, Raymond O. Fatig, Scott B. Bintrim, Richard H. Ffrench-Constant
  • Patent number: 6379946
    Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: April 30, 2002
    Assignee: Wisconsin Alumn Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, James K. Petell, Gregory L. Orr, Scott B. Bintrim, Todd A. Ciche, James A. Strickland, Raymond O. Fatig, Richard H. Ffrench-Constant
  • Patent number: 6048838
    Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.
    Type: Grant
    Filed: May 4, 1998
    Date of Patent: April 11, 2000
    Assignee: Dow AgroSciences LLC
    Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, Todd A. Ciche, James K. Petell, James A. Strickland, Gregory L. Orr, Raymond O. Fatig, Scott B. Bintrim, Richard H. Ffrench-Constant