Patents by Inventor Todd B. Vinzant
Todd B. Vinzant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7932054Abstract: The invention provides a thermal tolerant (thermostable) cellulase, AviIII, that is a member of the glycoside hydrolase (GH) family. AviIII was isolated and characterized from Acidothermus cellulolyticus, and, like many cellulases, the disclosed polypeptide and/or its derivatives may be useful for the conversion of biomass into biofuels and chemicals.Type: GrantFiled: April 16, 2009Date of Patent: April 26, 2011Assignee: Alliance for Sustainable Energy, LLCInventors: William S. Adney, Todd B. Vinzant, Shih-You Ding, Michael E. Himmel
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Publication number: 20100136667Abstract: The invention provides a thermal tolerant (thermostable) cellulase, AviIII, that is a member of the glycoside hydrolase (GH) family. AviIII was isolated and characterized from Acidothermus cellulolyticus, and, like many cellulases, the disclosed polypeptide and/or its derivatives may be useful for the conversion of biomass into biofuels and chemicals.Type: ApplicationFiled: April 16, 2009Publication date: June 3, 2010Applicant: ALLIANCE FOR SUSTAINABLE ENERGY, LLCInventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Patent number: 7538200Abstract: The invention provides a thermal tolerant (thermostable) cellulase, AviIII, that is a member of the glycoside hydrolase (GH) family. AviIII was isolated and characterized from Acidothermus cellulolyticus and, like many cellulases, the disclosed polypeptide and/or its derivatives may be useful for the conversion of biomass into biofuels and chemicals.Type: GrantFiled: October 18, 2002Date of Patent: May 26, 2009Assignee: Alliance for Sustainable Energy, LLCInventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Patent number: 7393673Abstract: The invention provides a thermal tolerant cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as Gux1. Gux1 has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified Gux1. Methods of making and using Gux1 polypeptides, including fusions, variants, and derivatives, are also disclosed.Type: GrantFiled: July 28, 2001Date of Patent: July 1, 2008Assignee: Midwest Research InstituteInventors: William S. Adney, Shi-You Ding, Todd B. Vinzant, Michael E. Himmel, Stephen R. Decker, Suzanne Lantz McCarter
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Patent number: 7375197Abstract: The disclosure provides a method for preparing an active exoglucanase in a heterologous host of eukaryotic origin. The method includes mutagenesis to reduce glycosylation of the exoglucanase when expressed in a heterologous host. It is further disclosed a method to produce variant cellobiohydrolase that is stable at high temperature through mutagenesis.Type: GrantFiled: January 14, 2002Date of Patent: May 20, 2008Assignee: MidWest Research InstituteInventors: William S. Adney, Stephen R. Decker, Suzanne Mc Carter, John O. Baker, Raphael Nieves, Michael E. Himmel, Todd B. Vinzant
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Patent number: 7364890Abstract: The invention provides a thermal tolerant (thermostable) cellulase, AviIII, that is a member of the glycoside hydrolase (GH) family. AviIII was isolated and characterized from Acidothermus cellulolyticus and, like many cellulases, the disclosed polypeptide and/or its derivatives may be useful for the conversion of biomass into biofuels and chemicals.Type: GrantFiled: July 28, 2001Date of Patent: April 29, 2008Assignee: Midwest Research InstituteInventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Patent number: 7306650Abstract: A method, and systems for implementing such method, for purifying and conditioning air of weaponized contaminants. The method includes wetting a filter packing media with a salt-based liquid desiccant, such as water with a high concentration of lithium chloride. Air is passed through the wetted filter packing media and the contaminants in are captured with the liquid desiccant while the liquid desiccant dehumidifies the air. The captured contaminants are then deactivated in the liquid desiccant, which may include heating the liquid desiccant. The liquid desiccant is regenerated by applying heat to the liquid desiccant and then removing moisture. The method includes repeating the wetting with the regenerated liquid desiccant which provides a regenerable filtering process that captures and deactivates contaminants on an ongoing basis while also conditioning the air. The method may include filtration effectiveness enhancement by electrostatic or inertial means.Type: GrantFiled: February 28, 2003Date of Patent: December 11, 2007Assignee: Midwest Research InstituteInventors: Steven J. Slayzak, Ren S. Anderson, Ronald D. Judkoff, Daniel M. Blake, Todd B. Vinzant, Joseph P. Ryan
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Patent number: 7112429Abstract: The invention provides a thermal tolerant mannanase that is a member of the glycoside hydrolase family. The invention further discloses this mannanase as ManA. ManA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified ManA. Methods of making ManA polypeptides, including fusions, variants, and derivatives, are also disclosed. Methods of using mannanase A, including for the processing of food and for use in food stuffs as bulking agents and the like, are also disclosed.Type: GrantFiled: July 28, 2001Date of Patent: September 26, 2006Assignee: Midwest Research InstituteInventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Patent number: 7059993Abstract: The invention provides a thermal tolerant cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as GuxA. GuxA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified GuxA. Methods of making and using GuxA polypeptides, including fusions, variants, and derivatives, are also disclosed.Type: GrantFiled: July 28, 2001Date of Patent: June 13, 2006Assignee: Midwest Research InstituteInventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel, Stephen R. Decker
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Publication number: 20040231512Abstract: A method, and systems for implementing such method, for purifying and conditioning air of weaponized contaminants. The method includes wetting a filter packing media with a salt-based liquid desiccant, such as water with a high concentration of lithium chloride. Air is passed through the wetted filter packing media and the contaminants in are captured with the liquid desiccant while the liquid desiccant dehumidifies the air. The captured contaminants are then deactivated in the liquid desiccant, which may include heating the liquid desiccant. The liquid desiccant is regenerated by applying heat to the liquid desiccant and then removing moisture. The method includes repeating the wetting with the regenerated liquid desiccant which provides a regenerable filtering process that captures and deactivates contaminants on an ongoing basis while also conditioning the air. The method may include filtration effectiveness enhancement by electrostatic or inertial means.Type: ApplicationFiled: November 7, 2003Publication date: November 25, 2004Inventors: Steven J. Slayzak, Ren S. Anderson, Ronald D. Judkoff, Daniel M. Blake, Todd B. Vinzant, Joseph P. Ryan
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Publication number: 20040038334Abstract: The invention provides a thermal tolerant (thermostable) cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as AviIII. AviIII has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified AviIII. Methods of making and using AviIII polypeptides, including fusions, variants, and derivatives, are also disclosed.Type: ApplicationFiled: July 28, 2001Publication date: February 26, 2004Inventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Publication number: 20030170861Abstract: A nucleic acid molecule having a nucleic acid sequence that encodes a linker region of exoglucanase, said nucleic acid sequence comprising the nucleic sequence 5′-GGCGGAAACCCGCCTGGCACCACC-3′.Type: ApplicationFiled: January 14, 2002Publication date: September 11, 2003Inventors: William S. Adney, Stephen R. Decker, Suzanne McCarter, John O. Baker, Rafael Nieves, Michael E. Himmel, Todd B. Vinzant
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Publication number: 20030119093Abstract: The invention provides a thermal tolerant mannanase that is a member of the glycoside hydrolase family. The invention further discloses this mannanase as ManA. ManA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified ManA. Methods of making ManA polypeptides, including fusions, variants, and derivatives, are also disclosed. Methods of using mannanase A, including for the processing of food and for use in food stuffs as bulking agents and the like, are also disclosed.Type: ApplicationFiled: July 28, 2001Publication date: June 26, 2003Inventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Publication number: 20030108988Abstract: An isolated polynucleotide molecule encoding a thermal stable AviIII polypeptide, said aviIII polypeptide comprising:Type: ApplicationFiled: October 18, 2002Publication date: June 12, 2003Inventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
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Publication number: 20030104522Abstract: The invention provides a thermal tolerant cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as GuxA. GuxA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified GuxA. Methods of making and using GuxA polypeptides, including fusions, variants, and derivatives, are also disclosed.Type: ApplicationFiled: July 28, 2001Publication date: June 5, 2003Inventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel, Stephen R. Decker
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Publication number: 20030096342Abstract: The invention provides a thermal tolerant cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as Gux1. Gux1 has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified Gux1. Methods of making and using Gux1 polypeptides, including fusions, variants, and derivatives, are also disclosed.Type: ApplicationFiled: July 28, 2001Publication date: May 22, 2003Inventors: William S. Adney, Shi-You Ding, Todd B. Vinzant, Michael E. Himmel, Stephen R. Decker, Suzanne Lantz McCarter
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Publication number: 20030054535Abstract: The invention provides a method for increasing the specific activity of a glycosyl hydrolase on a substrate, comprising replacing a hydrophobic surface binding amino acid of the hydrolase with a positively charged amino acid; and a method for increasing the specific activity of a glycosyl hydrolase on a substrate, comprising replacing an active site associated glycosyl-stabilizing amino acid of the hydrolase with an amino acid, the replacing amino acid not strongly retarding cellobiose from leaving the active site. The invention further provides mutant glycosyl hydrolases, which include Y245G, Y42R, and W82R.Type: ApplicationFiled: November 19, 2001Publication date: March 20, 2003Inventors: Michael E. Himmel, William S. Adney, John O. Baker, Todd B. Vinzant, Steven R. Thomas, Joshua Sakon, Stephen R. Decker
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Patent number: 6509184Abstract: A process for production of an alkaline tolerant dextranase enzyme comprises culturing a dextran-producing microorganism Streptomyces anulatus having accession no. ATCC PTA-3866 to produce an alkaline tolerant dextranase, Dex 1 wherein the protein in said enzyme is characterized by a MW of 63.3 kDa and Dex 2 wherein its protein is characterized by a MW of 81.8 kDa.Type: GrantFiled: August 24, 1999Date of Patent: January 21, 2003Assignee: Midwest Research InstituteInventors: Stephen R. Decker, William S. Adney, Todd B. Vinzant, Michael E. Himmel