Abstract: A method includes generating spectral projection data of a subject, including at least first spectral projection data corresponding to a first energy range and second spectral projection data corresponding to a second energy range, wherein the first and the second energy range are different. The method further includes constructing an image from a combination of the spectral projection data, and constructing a set of basis images for the 5 energy ranges and from the spectral projection data. The method further includes constructing a multi-dimensional histogram from the set of basis images, wherein the multi-dimensional histogram includes at least two axes, a first corresponding to a first basis component and a second corresponding to a second basis component, and the multi-dimensional histogram includes a set of clusters, including one cluster for each material 10 represented in the spectral projection data.

Abstract: The present invention includes a composition, method, method of making, and a kit for using an enteric contrast agent formulation comprising an enteric contrast medium comprising particles comprising atoms of an element with an atomic number from 70 to 77, and a pharmaceutically acceptable vehicle in which the particles are dispersed.

Abstract: A method includes generating spectral projection data of a subject, including at least first spectral projection data corresponding to a first energy range and second spectral projection data corresponding to a second energy range, wherein the first and the second energy range are different. The method further includes constructing an image from a combination of the spectral projection data, and constructing a set of basis images for the 5 energy ranges and from the spectral projection data. The method further includes constructing a multi-dimensional histogram from the set of basis images, wherein the multi-dimensional histogram includes at least two axes, a first corresponding to a first basis component and a second corresponding to a second basis component, and the multi-dimensional histogram includes a set of clusters, including one cluster for each material 10 represented in the spectral projection data.

Abstract: The present invention includes a method of resolving gold from iodine using a multi-detector Spectral Computed Tomography (CT) scanner comprising: obtaining an image using the scanner of a subject provided a gold contrast agent; performing a Spectral CT material differentiation or imaging at 140 kVp using one or more scanner tubes; and calculating a DE ratio for ratio of gold, wherein the DE ratio is about 1.0.

Abstract: The present invention includes a method of measuring thyroid function comprising identifying a subject in need of measuring thyroid function or structure; providing the subject with an amount of an organified iodine sufficient to cause thyroid follicular cell uptake; and obtaining sufficient spectral computed tomography images of the iodine uptake in thyroid cells over an amount of time sufficient to determine thyroid cellular function.