Patents by Inventor Todd C. Zankel

Todd C. Zankel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic receptor-associated protein (RAP) peptides
    Patent number: 8440629
    Abstract: The present invention relates generally to receptor-selective variants of the low-density lipoprotein receptor-associated protein (RAP) and compositions thereof, methods of generating such variants and methods of using such receptor-selective RAP variant compositions for therapeutic purposes.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: May 14, 2013
    Assignee: Raptor Pharmaceuticals Inc.
    Inventors: Christopher M. Starr, Todd C. Zankel
  • TREATMENT OF LIVER DISORDERS BY ADMINISTRATION OF RAP CONJUGATES
    Publication number: 20120251444
    Abstract: The present invention relates to the use of receptor-associate protein (RAP) and fragments and variants thereof to improve delivery of therapeutic compounds to the liver and provides methods to treat liver disorders and conditions, such as hepatic carcinoma, by administering RAP or RAP variants conjugated to active agents.
    Type: Application
    Filed: September 18, 2007
    Publication date: October 4, 2012
    Inventors: Christopher M. Starr, Todd C. Zankel
  • Method for Treating Liver Disorders with Receptor Associated Protein (RAP) Peptide-Fucosidase Inhibitor Conjugates
    Publication number: 20110189084
    Abstract: The present invention relates, in general, to methods and compositions for the treatment of liver disorders and liver tumors, such as hepatocellular carcinoma, with a peptide of the receptor associated protein (RAP) molecule conjugated to a fucosidase inhibitor.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 4, 2011
    Applicant: RAPTOR PHARMACEUTICAL INC.
    Inventor: Todd C. Zankel
  • Receptor associated protein (RAP) conjugates
    Patent number: 7829537
    Abstract: The present invention is directed to a methods and compositions for receptor mediated drug delivery, particularly across the blood-brain barrier.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: November 9, 2010
    Assignee: Raptor Pharmaceuticals Inc.
    Inventors: Todd C. Zankel, Christopher M. Starr
  • CYCLIC RECEPTOR-ASSOCIATED PROTEIN (RAP) PEPTIDES
    Publication number: 20100210517
    Abstract: The present invention relates generally to receptor-selective variants of the low-density lipoprotein receptor-associated protein (RAP) and compositions thereof, methods of generating such variants and methods of using such receptor-selective RAP variant compositions for therapeutic purposes.
    Type: Application
    Filed: March 21, 2008
    Publication date: August 19, 2010
    Applicant: Raptor Pharmaceutical Inc.
    Inventors: Christopher M. Starr, Todd C. Zankel
  • Compositions Comprising Receptor-Associated Protein (RAP) Variants Specific for CR-Containing Proteins and Uses Thereof
    Publication number: 20090281024
    Abstract: The present invention relates generally to receptor-selective variants of the low-density lipoprotein receptor-associated protein (RAP) and compositions thereof, methods of generating such variants and methods of using such receptor-selective RAP variant compositions for therapeutic purposes.
    Type: Application
    Filed: September 18, 2006
    Publication date: November 12, 2009
    Applicant: RAPTOR PHARMACEUTICAL INC.
    Inventors: Todd C. Zankel, Christopher M. Starr
  • Compositions Comprising Receptor-Associated Protein (RAP) Variants Specific for LRP2 and Uses Thereof
    Publication number: 20090269346
    Abstract: The present invention relates generally to receptor-selective variants of the low-density lipoprotein receptor-associated protein (RAP) and compositions thereof, methods of generating such variants and methods of using such receptor-selective RAP variant compositions for therapeutic purposes. The invention also relates to antibodies that bind to one or a small subset of CR-containing proteins.
    Type: Application
    Filed: June 14, 2006
    Publication date: October 29, 2009
    Applicant: RAPTOR PHARMACEUTICAL INC.
    Inventors: Christopher M. Starr, Todd C. Zankel
  • Manufacture of Highly Phosphorylated Lysosomal Enzymes and Uses Thereof
    Publication number: 20090191178
    Abstract: This invention provides compositions of highly phosphorylated lysosomal enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases.
    Type: Application
    Filed: July 30, 2008
    Publication date: July 30, 2009
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Todd C. Zankel, Christopher M. Starr
  • Manufacture of Highly Phosphorylated Lysosomal Enzymes and Uses Thereof
    Publication number: 20080014188
    Abstract: This invention provides compositions of highly phosphorylated lysosomal enzymes, their pharmaceutical compositions, methods of producing and purifying such compounds and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases.
    Type: Application
    Filed: February 7, 2005
    Publication date: January 17, 2008
    Inventors: Todd C. Zankel, Christopher M. Starr