Abstract: The present disclosure provides anti-tau antibodies and adeno-associated virus (AAV) particles with an AAV genome encoding anti-tau antibodies. Also provided are methods of using anti-tau antibodies and AAV particles for treatment and diagnosis of neurological indications.

Abstract: The present disclosure provides anti-tau antibodies and vectorization thereof (e.g., into AAV particles). Also provided are methods of using anti-tau antibodies and/or AAV particles for prevention, treatment, and/or diagnosis of neurological indications.

Abstract: The present disclosure provides anti-tau antibodies and vectorization thereof (e.g., into AAV particles). Also provided are methods of using anti-tau antibodies and/or AAV particles for prevention, treatment, and/or diagnosis of neurological indications.

Abstract: A furniture accessory may include an outer body configured to connect to a furniture item, and a receptacle slidably supported in the outer body. The receptacle may be configured to receive a beverage container therein. The top end of the inner receptacle is axially spaced from and above the top end of the outer body when the inner receptacle is in each of a retracted and extended position.

Abstract: A video editor is configured to create and edit video content. These configurations provide tools to create shorter segments or video “moments” from longer video content. The tools may permit an end user to embedded information that identifies objects that appear in the short video segments. In one implementation, the video editor can provide interactive tools for the end use to manually create, edit, and “tag” objects in the shorter segment. The video editor may alternatively create a listing of text or transcription. The end user may, in turn, interact with this listing to create the smaller segments of the video content. Once complete, the tools may allow the end user to publish the shorter segments individually or as a collection through their own channels or social media, which may, inter alia, drive consumer views and customer conversion to the identified products and goods.

Abstract: The present disclosure provides anti-tau antibodies. Also provided are methods of using anti-tau antibodies for treatment and diagnosis of neurological indications.

Abstract: A convertible bed may have a headboard including one or more panels and one or more functional features disposed on the headboard. The functional features may be electronic features. The functional features may be concealed by the headboard in a closed configuration where the headboard appears uniform. In an open configuration one or more functional features on the headboard are visible. The convertible bed may include one or more of an ambient lighting source, a motion sensor operative to control the ambient lighting source, a multifunctional supporting leg, and a power button.

Abstract: The disclosure provides compositions and methods for the preparation, manufacture and therapeutic use of viral vectors, such as adeno-associated virus (AAV) particles having viral genomes encoding one or more antibodies or antibody fragments or antibody-like polypeptides, for the prevention and/or treatment of diseases and/or disorders.

Abstract: The invention provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.

Abstract: The present disclosure provides anti-tau antibodies and vectorization thereof (e.g., into AAV particles). Also provided are methods of using anti-tau antibodies and/or AAV particles for prevention, treatment, and/or diagnosis of neurological indications.

Abstract: The present disclosure provides compositions and methods for the preparation, manufacture and therapeutic use of viral vectors, such as adeno-associated virus (AAV) particles having viral genomes encoding one or more antibodies or antibody fragments or antibody-like polypeptides, for the prevention and/or treatment of diseases and/or disorders.

Abstract: The invention provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.

Abstract: The disclosure provides compositions and methods for the preparation, manufacture and therapeutic use of viral vectors, such as adeno-associated virus (AAV) particles having viral genomes encoding one or more antibodies or antibody fragments or antibody-like polypeptides, for the prevention and/or treatment of diseases and/or disorders.

Abstract: The present disclosure relates to pharmaceutical compositions of adeno-associated viral (AAV) particles encoding siRNA molecules and methods for treating Huntington's Disease (HD).

Abstract: The disclosure provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.

Abstract: The present disclosure describes methods and systems for use in the production of adeno-associated virus (AAV) particles and AAV formulations, including recombinant adeno-associated virus (rAAV) particles and formulations. In certain embodiments, the present disclosure presents methods and systems for clarifying, purifying, formulating, filtering and processing AAV particles and AAV formulations. The present disclosure also describes compositions, methods and processes for the design, preparation, manufacture, use and/or formulation of AAV particles comprising modulatory polynucleotides, e.g., polynucleotides encoding small interfering RNA (siRNA) molecules which target the Huntingtin (HTT) gene (e.g., the wild-type or the mutated CAG-expanded HTT gene). Methods for using formulated AAV particles comprising modulatory polynucleotides to inhibit the HTT gene expression in a subject with a neurodegenerative disease (e.g., Huntington's Disease (HD)) are also disclosed.

Abstract: The disclosure provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.

Abstract: The invention provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.

Abstract: Seats and methods to assemble a seat are disclosed. A method to assemble a seat includes positioning a left arm and a right arm over a seat frame, each of the left and right arms having fabric that covers a left side and a right side of the respective arm. The method also includes wrapping the fabric of the left arm around a left side of the seat frame to cover the left side of the seat frame, and wrapping the fabric of the right arm around a right side of the seat frame to cover the right side of the seat frame. The method further includes positioning a back frame over the seat frame, wrapping fabric of the back frame around a back side of the seat frame to cover the back side of the seat frame, and securing the left and right arms to the seat frame.