Abstract: Tissue puncture devices, and systems and methods for accessing tissue (e.g., cardiovascular tissue) according to the present disclosure may include a tubular sheath extending along a longitudinal axis, the tubular sheath having a proximal end and a distal end, a needle disposed coaxially in the sheath, the needle having a proximal end and a distal end and being movable along the longitudinal axis of sheath, and a needle control mechanism disposed at the proximal end of the needle, the needle control mechanism being configured to lock the distal end of the needle in a first position retracted within the distal end of the sheath, and release the needle to an unlocked second position such that the distal end of the needle is extendable beyond the distal end of the sheath.

Abstract: Tissue puncture devices, and systems and methods for accessing tissue (e.g., cardiovascular tissue) according to the present disclosure may include a tubular sheath extending along a longitudinal axis, the tubular sheath having a proximal end and a distal end, a needle disposed coaxially in the sheath, the needle having a proximal end and a distal end and being movable along the longitudinal axis of sheath, and a needle control mechanism disposed at the proximal end of the needle, the needle control mechanism being configured to lock the distal end of the needle in a first position retracted within the distal end of the sheath, and release the needle to an unlocked second position such that the distal end of the needle is extendable beyond the distal end of the sheath.

Abstract: The present disclosure relates generally to apparatuses and methods for delivering an occlusion device to a paravalvular leak. In some embodiments, a paravalvular occlusion apparatus includes a catheter having main body including a proximal end and a distal end, a visualization element disposed in the distal end of the main body, and a working channel extending from the distal end of the main body. The catheter further includes an elongate shaft extendable from the working channel, wherein an occlusion device is coupled to the elongate shaft. In some embodiments, an occlusion device includes a leading end including a first section, and a trailing end opposite the leading end, the trailing end including a second section. The first section and the second section of the occlusion device are operable to be positioned along a perimeter of a prosthetic valve for blocking the paravalvular leak.

Abstract: Anchor delivery systems and methods for repairing a valve inside a body, such as a heart valve, may include a delivery catheter having a distal end comprised of two or more rotatably coupled knuckles. An anchor delivery mechanism is disposed distally of the two or more knuckles, and includes a first pincer arm having a distal end and a proximal end rotatably coupled to a distal end of the anchor delivery mechanism at a first connection point, and a second pincer arm having a distal end and a proximal end rotatably coupled to the distal end of the anchor delivery mechanism at a second connection point opposite the first connection point. In a closed position, the distal ends of the first and second pincer arms are positioned together. In an open position, the distal ends of the first and second pincer arms are rotated apart from each other.

Abstract: Apparatuses, systems, and methods for crossing a tissue region may include a catheter and a tip section arranged therewith. The tip section may be configured to puncture the tissue region and create an opening therein, dilate the opening in the tissue region, and pass through the opening.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for applying ablation therapy to a tissue region. The apparatuses, systems, and methods may include a balloon structure and one or more electrodes arranged on or within the balloon structure and configured to deliver energy to the tissue region.

Abstract: According to an aspect of the present disclosure, a medical device may include a deflation catheter assembly. The deflation catheter assembly may include a tubular member having an outer surface, an inner surface, and a central lumen defined by the inner surface. The deflation catheter assembly may also include a plurality of passages extending through a side of the tubular member and from the inner surface to the outer surface. The deflation catheter assembly may also include an anchoring member coupled to the tubular member. A distal portion of the tubular member may extend distal the anchoring member. The plurality of passages may be at the distal portion of the tubular member. The anchoring member may be configured to move between an unexpanded state and an expanded state. At least a portion of the anchoring member may protrude radially outwardly from the outer surface of the tubular member when the anchoring member is in the expanded state.

Abstract: Tissue puncture devices, and systems and methods for accessing tissue (e.g., cardiovascular tissue) according to the present disclosure may include a tubular sheath extending along a longitudinal axis, the tubular sheath having a proximal end and a distal end, a needle disposed coaxially in the sheath, the needle having a proximal end and a distal end and being movable along the longitudinal axis of sheath, and a needle control mechanism disposed at the proximal end of the needle, the needle control mechanism being configured to lock the distal end of the needle in a first position retracted within the distal end of the sheath, and release the needle to an unlocked second position such that the distal end of the needle is extendable beyond the distal end of the sheath.

Abstract: According to aspects of the present disclosure, a system may include a loading device including an exterior surface. The system may also include an expandable member mounted on the exterior surface of the loading device. The expandable member may be configured to selectively transition between a collapsed state and an expanded state. The system may also include a covering mounted on the expandable member. The covering may extend around the expandable member and the loading device. The loading device may be configured to position the expandable member and the covering for mounting on an exterior surface of an elongate introduction sheath.

Abstract: The present disclosure relates generally to apparatuses and methods for delivering an occlusion device to a paravalvular leak. In some embodiments, a paravalvular occlusion apparatus includes a catheter having main body including a proximal end and a distal end, a visualization element disposed in the distal end of the main body, and a working channel extending from the distal end of the main body. The catheter further includes an elongate shaft extendable from the working channel, wherein an occlusion device is coupled to the elongate shaft. In some embodiments, an occlusion device includes a leading end including a first section, and a trailing end opposite the leading end, the trailing end including a second section. The first section and the second section of the occlusion device are operable to be positioned along a perimeter of a prosthetic valve for blocking the paravalvular leak.

Abstract: According to aspects of the present disclosure, a retrieval catheter assembly for retrieving an intragastric balloon may include a tubular member configured to pass through a wall of the intragastric balloon. The retrieval catheter assembly may also include a retrieval member coupled to the tubular member and movable between an undeployed configuration and a deployed configuration. In the undeployed configuration the retrieval member may be substantially aligned with the tubular member. In the deployed configuration at least a portion of the retrieval member may diverge from the tubular member and may be configured to engage the wall of the intragastric balloon.

Abstract: Anchor delivery systems and methods for repairing a valve inside a body, such as a heart valve, may include a delivery catheter having a distal end comprised of two or more rotatably coupled knuckles. An anchor delivery mechanism is disposed distally of the two or more knuckles, and includes a first pincer arm having a distal end and a proximal end rotatably coupled to a distal end of the anchor delivery mechanism at a first connection point, and a second pincer arm having a distal end and a proximal end rotatably coupled to the distal end of the anchor delivery mechanism at a second connection point opposite the first connection point. In a closed position, the distal ends of the first and second pincer arms are positioned together. In an open position, the distal ends of the first and second pincer arms are rotated apart from each other.

Abstract: A spring element for a contact force sensing medical catheter. The spring element includes a first ring, a second ring spaced apart from the first ring, a plurality of struts connecting the first ring to the second ring, and a plurality of interlocking features. The second ring and the first ring are coaxially aligned with a longitudinal axis of the spring element. The plurality of struts is configured to permit elastic, relative axial and radial displacement between the first ring and the second ring. The plurality of interlocking features is configured to limit the relative axial and radial displacement between the first ring and the second ring.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for crossing a tissue region. The apparatuses, systems, and methods may include a catheter and a tip section arranged therewith. The tip section may be configured to puncture the tissue region and create an opening therein, dilate the opening in the tissue region, and pass through the opening.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for applying ablation therapy to a tissue region. The apparatuses, systems, and methods may include a balloon structure and one or more electrodes arranged on or within the balloon structure and configured to deliver energy to the tissue region.

Abstract: According to aspects of the present disclosure, a system may include a loading device including an exterior surface. The system may also include an expandable member mounted on the exterior surface of the loading device. The expandable member may be configured to selectively transition between a collapsed state and an expanded state. The system may also include a covering mounted on the expandable member. The covering may extend around the expandable member and the loading device. The loading device may be configured to position the expandable member and the covering for mounting on an exterior surface of an elongate introduction sheath.

Abstract: According to an aspect of the present disclosure, a medical device may include a deflation catheter assembly. The deflation catheter assembly may include a tubular member having an outer surface, an inner surface, and a central lumen defined by the inner surface. The deflation catheter assembly may also include a plurality of passages extending through a side of the tubular member and from the inner surface to the outer surface. The deflation catheter assembly may also include an anchoring member coupled to the tubular member. A distal portion of the tubular member may extend distal the anchoring member. The plurality of passages may be at the distal portion of the tubular member. The anchoring member may be configured to move between an unexpanded state and an expanded state. At least a portion of the anchoring member may protrude radially outwardly from the outer surface of the tubular member when the anchoring member is in the expanded state.

Abstract: According to aspects of the present disclosure, a retrieval catheter assembly for retrieving an intragastric balloon may include a tubular member configured to pass through a wall of the intragastric balloon. The retrieval catheter assembly may also include a retrieval member coupled to the tubular member and movable between an undeployed configuration and a deployed configuration. In the undeployed configuration the retrieval member may be substantially aligned with the tubular member. In the deployed configuration at least a portion of the retrieval member may diverge from the tubular member and may be configured to engage the wall of the intragastric balloon.