Patents by Inventor Todd HEIL

Todd HEIL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TARGETED THERAPEUTIC DELIVERY TO BONE
    Publication number: 20250179136
    Abstract: Provided herein are polypeptides comprising a therapeutic targeted for delivery to an organ or tissue, and uses thereof.
    Type: Application
    Filed: February 20, 2025
    Publication date: June 5, 2025
    Inventors: Luis ALVAREZ, David STEWART, Hyeon PARK, Todd HEIL
  • Compositions and methods for targeted therapeutic delivery to bone
    Patent number: 12264187
    Abstract: Provided herein are polypeptides comprising a therapeutic targeted for delivery to an organ or tissue, and uses thereof.
    Type: Grant
    Filed: October 14, 2022
    Date of Patent: April 1, 2025
    Assignee: Theradaptive, Inc.
    Inventors: Luis Alvarez, David Stewart, Hyeon Park, Todd Heil
  • CERAMIC COMPOSITIONS AND METHODS OF USE
    Publication number: 20240226383
    Abstract: The present disclosure provides devices comprising a therapeutic agent bound to a printed three-dimensional structure. Ink formulations for three-dimensional printing are also disclosed. Additionally, provided herein are methods for manufacturing devices and uses there e.g., in treating a condition in a subject in need thereof. The devices may be coated with therapeutic agents, such as those that promo bone growth, and/or seeded with cells to generate devices for use in tissue replacement and grafting.
    Type: Application
    Filed: February 23, 2022
    Publication date: July 11, 2024
    Inventors: Luis ALVAREZ, Todd HEIL
  • CERAMIC COMPOSITIONS AND METHODS OF USE
    Publication number: 20240131228
    Abstract: The present disclosure provides devices comprising a therapeutic agent bound to a printed three-dimensional structure. Ink formulations for three-dimensional printing are also disclosed. Additionally, provided herein are methods for manufacturing devices and uses there e.g., in treating a condition in a subject in need thereof. The devices may be coated with therapeutic agents, such as those that promo bone growth, and/or seeded with cells to generate devices for use in tissue replacement and grafting.
    Type: Application
    Filed: February 23, 2022
    Publication date: April 25, 2024
    Inventors: Luis ALVAREZ, Todd HEIL
  • COMPOSITIONS AND METHODS FOR TARGETED THERAPEUTIC DELIVERY TO BONE
    Publication number: 20230235002
    Abstract: Provided herein are polypeptides comprising a therapeutic targeted for delivery to an organ or tissue, and uses thereof.
    Type: Application
    Filed: October 14, 2022
    Publication date: July 27, 2023
    Inventors: Luis ALVAREZ, David STEWART, Hyeon PARK, Todd HEIL
  • THERAPEUTIC COMPOSITIONS COMPRISING GRAFT MATERIALS AND BETA-TCP BINDING PEPTIDES AND USES THEREOF
    Publication number: 20230203115
    Abstract: Provided herein are polypeptides that include one or more ?-tricalcium phosphate (?TCP)-binding sequence(s) and uses thereof.
    Type: Application
    Filed: January 5, 2021
    Publication date: June 29, 2023
    Inventors: Luis ALVAREZ, Todd HEIL, David Hunt STEWART, Hyeon PARK
  • MATERIALS FOR DELIVERY OF TETHERABLE PROTEINS IN BONE IMPLANTS
    Publication number: 20220323641
    Abstract: The present disclosure provides devices comprising a therapeutic agent bound to a printed three-dimensional structure. The printed three-dimensional structure comprises about 50% to about 100% by weight ceramic and about 0% to about 50% by weight N polymer. Ink formulations for three-dimensional printing are also disclosed. Additionally, provided herein are methods for manufacturing devices and uses thereof, e.g., in treating a condition in a subject in need thereof.
    Type: Application
    Filed: August 19, 2020
    Publication date: October 13, 2022
    Inventors: Luis ALVAREZ, Todd HEIL