Patents by Inventor Todd Hoare

Todd Hoare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stimulus activated cork-shell capsules
    Patent number: 11883540
    Abstract: The present application relates to a vehicle whose shell material is modified with at least one additional secondary phase that acts as a cork. In the presence of an energy source (preferably ultrasound), the corks embedded in the shell are either removed from the shell to create permanent pores or perturbed within the shell to create transient pores that can control transport in or out of the vehicle.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: January 30, 2024
    Assignee: McMaster University
    Inventors: Todd Hoare, Jonathan Dorogin, David Koff, Andrew Singh
  • IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF
    Publication number: 20230220166
    Abstract: The disclosure relates to an in situ-gelling hydrogel composition based on functionalized zwitterionic polymers. The resulting hydrogels exhibit highly anti-fouling, anti-adhesive, and lubricating properties to enable the fabrication of bulk hydrogels or hydrogel-based coatings of relevance to biomedical applications.
    Type: Application
    Filed: May 28, 2021
    Publication date: July 13, 2023
    Inventors: Todd Hoare, Jonathan Dorogin, Zhicheng Pan, Nahieli Iyeida Preciado Rivera
  • DIFFERENTIAL SIGNAL BIOSENSING FOR DETECTING AN ANALYTE
    Publication number: 20220317082
    Abstract: The present application relates to a biosensor for detecting an analyte comprising a first and second working electrode; a detection probe functionalized on the first working electrode, the detection probe comprising a reporter moiety and a recognition moiety for an analyte; a capture probe functionalized on the second working electrode; and a counter electrode. Each working electrode is configured to provide a change in signal if the analyte is present. The biosensor can be used to detect an analyte in a sample.
    Type: Application
    Filed: March 20, 2020
    Publication date: October 6, 2022
    Applicant: MCMASTER UNIVERSITY
    Inventors: Leyla SOLEYMANI, Richa PANDEY, Yingfu LI, Todd HOARE, Dingran CHANG, Yang LU
  • IN SITU GELLING POLYSACCHARIDE-BASED NANOPARTICLE HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF
    Publication number: 20210361570
    Abstract: The present application relates to in situ gelling hydrogel structures formed by the crosslinking of polysaccharide-based nanoparticles and functional polymers. Such systems can be designed to release the nanoparticles and/or encapsulated therapeutics either over time or in response to environmental stimuli.
    Type: Application
    Filed: May 18, 2021
    Publication date: November 25, 2021
    Inventors: Todd Hoare, Ali Babar, Michael J. Majcher, Xiaoyun Li, Andrew D. Lofts, Matthew A. Campea
  • STIMULUS ACTIVATED CORK-SHELL CAPSULES
    Publication number: 20210353550
    Abstract: The present application relates to a vehicle whose shell material is modified with at least one additional secondary phase that acts as a cork. In the presence of an energy source (preferably ultrasound), the corks embedded in the shell are either removed from the shell to create permanent pores or perturbed within the shell to create transient pores that can control transport in or out of the vehicle.
    Type: Application
    Filed: May 14, 2021
    Publication date: November 18, 2021
    Inventors: Todd Hoare, Jonathan Dorogin, David Koff, Andrew Singh
  • Brush amphiphilic block copolymers, and self-assembled nanoparticles therefrom
    Patent number: 10774169
    Abstract: The present application relates to brush amphiphilic block copolymers comprising at least one block which is hydrophilic and at least another block which is hydrophobic.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: September 15, 2020
    Assignee: McMaster University
    Inventors: Lukas Sadowski, Todd Hoare, Haiming (Daniel) Luo, Maryam Badv
  • PRINTABLE HYDROGELS FOR BIOMOLECULE IMMOBILIZATION AND STABILIZATION
    Publication number: 20200256860
    Abstract: The invention pertains to a printable hydrogel that can both immobilize and stabilize a wide range of biomolecules and/or cells on a substrate while restricting the access of surrounding chemicals to the biomolecule active site. Such hydrogels can be adapted to high-throughput screening applications and can discriminate between true inhibitors and promiscuous aggregating inhibitors as well as enable the determination of dose-response relationships of biomolecule and/or cell inhibitory chemicals with high accuracy.
    Type: Application
    Filed: February 10, 2020
    Publication date: August 13, 2020
    Inventors: Rabia Mateen, Monsur Ali, Todd Hoare
  • POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF
    Publication number: 20190321512
    Abstract: The present application relates to hydrogel compositions comprising first and second precursor polymers, wherein the precursor polymers are modified poly(oligoethylene glycol methacrylate) copolymers that are crosslinked through electrophile-nucleophile reactions.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 24, 2019
    Inventors: Todd Hoare, Emilia Bakaic, Niels M.B. Smeets, Xudong Deng
  • Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof
    Patent number: 10363340
    Abstract: The present application relates to hydrogel compositions comprising first and second precursor polymers, wherein the precursor polymers are modified poly(oligoethylene glycol methacrylate) copolymers that are crosslinked through electrophile-nucleophile reactions.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: July 30, 2019
    Assignee: McMaster University
    Inventors: Todd Hoare, Emilia Bakaic, Niels M. B. Smeets, Xudong Deng
  • BRUSH AMPHIPHILIC BLOCK COPOLYMERS, AND SELF-ASSEMBLED NANOPARTICLES THEREFROM
    Publication number: 20180009924
    Abstract: The present application relates to brush amphiphilic block copolymers comprising at least one block which is hydrophilic and at least another block which is hydrophobic.
    Type: Application
    Filed: July 11, 2017
    Publication date: January 11, 2018
    Inventors: Lukas Sadowski, Todd Hoare, Haiming (Daniel) Luo, Maryam Badv
  • POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF
    Publication number: 20160151535
    Abstract: The present application relates to hydrogel compositions comprising first and second precursor polymers, wherein the precursor polymers are modified poly(oligoethylene glycol methacrylate) copolymers that are crosslinked through electrophile-nucleophile reactions.
    Type: Application
    Filed: November 4, 2015
    Publication date: June 2, 2016
    Inventors: Todd Hoare, Emilia Bakaic, Niels M.B. Smeets, Xudong Deng
  • METHOD FOR THE PREPARATION OF DEGRADABLE MICROGEL PARTICLES, AND MICROGEL COMPOSITIONS THEREOF
    Publication number: 20160106676
    Abstract: The present application relates to an aqueous method for the preparation of microgel particles using a stimuli-responsive prepolymer
    Type: Application
    Filed: October 19, 2015
    Publication date: April 21, 2016
    Inventors: Todd Hoare, Daryl Sivakumaran, Madeline Simpson, Eva Mueller