Patents by Inventor Todd Holmes
Todd Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240001152Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: ApplicationFiled: September 14, 2023Publication date: January 4, 2024Inventors: Christof BALTES, Todd HOLMES
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Patent number: 11786758Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: GrantFiled: May 26, 2021Date of Patent: October 17, 2023Assignees: SIEMENS HEALTHINEERS INTERNATIONAL AG, VARIAN MEDICAL SYSTEMS, INC.Inventors: Christof Baltes, Todd Holmes
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Publication number: 20210283427Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: ApplicationFiled: May 26, 2021Publication date: September 16, 2021Inventors: Christof BALTES, Todd HOLMES
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Patent number: 11090512Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: GrantFiled: April 10, 2020Date of Patent: August 17, 2021Assignees: VARIAN MEDICAL SYSTEMS, INC., VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventors: Christof Baltes, Todd Holmes
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Patent number: 10969083Abstract: A flashlight that includes a body with a first end and a second end. A first side protrusion extends outwardly from the body and a second side protrusion extends outwardly from another side of the body. A cover apparatus is engaged to the first end, and a button assembly is engaged to the second end. A light assembly is disposed within the body for projecting light outwardly from the first end of the body.Type: GrantFiled: February 28, 2019Date of Patent: April 6, 2021Inventor: Darryl Todd Holmes
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Publication number: 20200278104Abstract: A flashlight that includes a body with a first end and a second end. A first side protrusion extends outwardly from the body and a second side protrusion extends outwardly from another side of the body. A cover apparatus is engaged to the first end, and a button assembly is engaged to the second end. A light assembly is disposed within the body for projecting light outwardly from the first end of the body.Type: ApplicationFiled: February 28, 2019Publication date: September 3, 2020Inventor: Darryl Todd HOLMES
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Publication number: 20200238103Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: ApplicationFiled: April 10, 2020Publication date: July 30, 2020Inventors: Christof BALTES, Todd HOLMES
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Patent number: 10682527Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: GrantFiled: January 16, 2019Date of Patent: June 16, 2020Assignees: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG, VARIAN MEDICAL SYSTEMS, INC.Inventors: Christof Baltes, Todd Holmes
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Publication number: 20190160308Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: ApplicationFiled: January 16, 2019Publication date: May 30, 2019Inventors: Christof BALTES, Todd HOLMES
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Patent number: 10286229Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: GrantFiled: January 21, 2016Date of Patent: May 14, 2019Assignees: VARIAN MEDICAL SYSTEMS, INC., VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventors: Christof Baltes, Todd Holmes
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Publication number: 20160136460Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: ApplicationFiled: January 21, 2016Publication date: May 19, 2016Inventors: Christof BALTES, Todd HOLMES
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Patent number: 9265971Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: GrantFiled: February 7, 2014Date of Patent: February 23, 2016Assignees: Varian Medical Systems, Inc., Varian Medical Systems International AGInventors: Christof Baltes, Todd Holmes
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Publication number: 20150241069Abstract: A cooking oven includes a first heatable oven chamber, a second heatable oven chamber below the first oven chamber. A cooling plenum is located above the first oven chamber including a suction portion to supply cool air and an exhaust portion to discharge heated air. A cooling fan produces a primary cooling airflow through the cooling plenum. An electronic device is located at least partially within the cooling plenum and in flow communication with the heated air. A bypass element is located within the cooling plenum that at least partially surrounds the electronic device to divert the heated air away from the electronic device. In one example, the cooling fan produces a secondary cooling airflow through a vertical channel at the rear of the cooking oven. In another example, a second cooling plenum is located above the second oven chamber.Type: ApplicationFiled: February 27, 2014Publication date: August 27, 2015Applicant: Electrolux Home Products, Inc.Inventors: Ronald Gene Brant, Aaron Todd Holmes
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Publication number: 20150224342Abstract: A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.Type: ApplicationFiled: February 7, 2014Publication date: August 13, 2015Applicants: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG, VARIAN MEDICAL SYSTEMS, INC.Inventors: Christof BALTES, Todd HOLMES
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Publication number: 20070190603Abstract: Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino acids, are complementary and are structurally compatible. Specifically, two peptides, (AEAEAKAK)2 (ARARADAD)2, were shown to self-assemble into macroscopic membranes. Conditions under which the peptides self-assemble into macroscopic membranes and methods for producing the membranes are also described. The macroscopic membranes have several interesting properties: they are stable in aqueous solution, serum, and ethanol, are highly resistant to heat, alkaline and acidic pH, chemical denaturants, and proteolytic digestion, and are non-cytotoxic.Type: ApplicationFiled: August 29, 2006Publication date: August 16, 2007Inventors: Todd Holmes, Shuguang Zhang, Alexander Rich, C. DiPersio, Curtis Lockshin
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Patent number: 7098028Abstract: Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino acids, are complementary and are structurally compatible. Specifically, two peptides, (AEAEAKAK)2 (ARARADAD)2, were shown to self-assemble into macroscopic membranes. Conditions under which the peptides self-assemble into macroscopic membranes and methods for producing the membranes are also described. The macroscopic membranes have several interesting properties: they are stable in aqueous solution, serum, and ethanol, are highly resistant to heat, alkaline and acidic pH, chemical denaturants, and proteolytic digestion, and are non-cytotoxic.Type: GrantFiled: March 17, 2003Date of Patent: August 29, 2006Assignee: Massachusetts Institute of TechnologyInventors: Todd Holmes, Shuguang Zhang, Alexander Rich, C. Michael DiPersio, Curtis Lockshin
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Patent number: 6800481Abstract: Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino acids, are complementary and are structurally compatible. Specifically, two peptides, (AEAEAKAK)2 (ARARADAD)2, were shown to self-assemble into macroscopic membranes. Conditions under which the peptides self-assemble into macroscopic membranes and methods for producing the membranes are also described. The macroscopic membranes have several interesting properties: they are stable in aqueous solution, serum, and ethanol, are highly resistant to heat, alkaline and acidic pH, chemical denaturants, and proteolytic digestion, and are non-cytotoxic.Type: GrantFiled: March 26, 1997Date of Patent: October 5, 2004Assignee: Massachusetts Institute of TechnologyInventors: Todd Holmes, Shuguang Zhang, Alexander Rich, C. Michael DiPersio, Curtis Lockshin
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Publication number: 20040087013Abstract: Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino acids, are complementary and are structurally compatible. Specifically, two peptides, (AEAEAKAK)2 (ARARADAD)2, were shown to self-assemble into macroscopic membranes. Conditions under which the peptides self-assemble into macroscopic membranes and methods for producing the membranes are also described. The macroscopic membranes have several interesting properties: they are stable in aqueous solution, serum, and ethanol, are highly resistant to heat, alkaline and acidic pH, chemical denaturants, and proteolytic digestion, and are non-cytotoxic.Type: ApplicationFiled: March 17, 2003Publication date: May 6, 2004Inventors: Todd Holmes, Shuguang Zhang, Alexander Rich, C. Michael DiPersio, Curtis Lockshin
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Patent number: 6548630Abstract: Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino acids, are complementary and are structurally compatible. Specifically, two peptides, (AEAEAKAK)2 (ARARADAD)2, were shown to self-assemble into macroscopic membranes. Conditions under which the peptides self-assemble into macroscopic membranes and methods for producing the membranes are also described. The macroscopic membranes have several interesting properties: they are stable in aqueous solution, serum, and ethanol, are highly resistant to heat, alkaline and acidic pH, chemical denaturants, and proteolytic digestion, and are non-cytotoxic.Type: GrantFiled: July 22, 1997Date of Patent: April 15, 2003Assignee: Massachusettes Insitute of TechnologyInventors: Shuguang Zhang, Curtis Lockshin, Alexander Rich, Todd Holmes
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Patent number: D913552Type: GrantFiled: February 28, 2019Date of Patent: March 16, 2021Inventor: Darryl Todd Holmes