Patents by Inventor Todd K. Jones

Todd K. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbamate compounds and methods of making and using same
    Patent number: 12018004
    Abstract: This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: June 25, 2024
    Assignees: H. LUNDBECK A/S, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Justin S. Cisar, Cheryl A. Grice, Todd K. Jones, Micah J. Niphakis, Jae Won Chang, Kenneth M. Lum, Benjamin F. Cravatt
  • Crystalline forms of a MAGL inhibitor
    Patent number: 11993588
    Abstract: Described herein is the MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate, including crystalline forms and pharmaceutically acceptable salts and solvates thereof.
    Type: Grant
    Filed: September 8, 2021
    Date of Patent: May 28, 2024
    Assignee: H. LUNDBECK A/S
    Inventors: Cheryl A. Grice, Todd K. Jones, Kurt G. Grimm, Jacqueline Lorayne Blankman, Channing Rodney Beals
  • Carbamate compounds and methods of making and using same
    Patent number: 11530189
    Abstract: This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: December 20, 2022
    Assignees: H. LUNDBECKA/S, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Justin S. Cisar, Cheryl A. Grice, Todd K. Jones, Micah J. Niphakis, Jae Won Chang, Kenneth M. Lum, Benjamin F. Cravatt
  • Systems and methods for identifying available services at a physical address
    Patent number: 11153719
    Abstract: A system described herein may determine location information (e.g., two-dimensional location information) associated with an asset, generate or receive a first code based on the received location information, determine height information associated with the asset; generate a second code based on the first code and the height information; and store association information associating the first asset with the second code. The system may further receive a first request for location information associated with the asset; and output, in response to the first request, the second code, thus providing three-dimensional location information for the asset in response to the request.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: October 19, 2021
    Assignee: Verizon Patent and Licensing Inc.
    Inventors: Randolph Torres, Ashuma Singh Kaul, Todd K. Jones, Ravi K. Sharma, Peter D. Maxwell, Sandeep Juneja
  • Spirocycle compounds and methods of making and using same
    Patent number: 11142526
    Abstract: Provided herein are compounds and compositions useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: October 12, 2021
    Assignee: H. LUNDBECK A/S
    Inventors: Cheryl A. Grice, Olivia D. Weber, Daniel J. Buzard, Michael B. Shaghafi, Todd K. Jones
  • Crystalline forms of a MAGL inhibitor
    Patent number: 11142517
    Abstract: Described herein is the MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate, including crystalline forms and pharmaceutically acceptable salts and solvates thereof.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: October 12, 2021
    Assignee: H. LUNDBECK A/S
    Inventors: Cheryl A. Grice, Todd K. Jones, Kurt G. Grimm, Jacqueline Lorayne Blankman, Channing Rodney Beals
  • Methods of treating inflammation or neuropathic pain
    Patent number: 11034674
    Abstract: Provided herein are methods of treating inflammation or neuropathic pain using an effective dose of a monoacylglycerol lipase inhibitor or a composition thereof.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: June 15, 2021
    Assignee: H. LUNDBECK A/S
    Inventors: Jacqueline Lorayne Blankman, Jason Robert Clapper, R. Alan B. Ezekowitz, Iain Peter Fraser, Cheryl A. Grice, Todd K. Jones, Gary Paul O'Neill, Archie Wayne Thurston, Jr., Channing Rodney Beals
  • Carbamate compounds and methods of making and using same
    Patent number: 11021453
    Abstract: This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for a method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: June 1, 2021
    Assignees: LUNDBECK LA JOLLA RESEARCH CENTER, INC., THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Justin S. Cisar, Cheryl A. Grice, Todd K. Jones, Micah J. Niphakis, Jae Won Chang, Kenneth M. Lum, Benjamin F. Cravatt
  • SYSTEMS AND METHODS FOR IDENTIFYING AVAILABLE SERVICES AT A PHYSICAL ADDRESS
    Publication number: 20210160660
    Abstract: A system described herein may determine location information (e.g., two-dimensional location information) associated with an asset, generate or receive a first code based on the received location information, determine height information associated with the asset; generate a second code based on the first code and the height information; and store association information associating the first asset with the second code. The system may further receive a first request for location information associated with the asset; and output, in response to the first request, the second code, thus providing three-dimensional location information for the asset in response to the request.
    Type: Application
    Filed: August 27, 2020
    Publication date: May 27, 2021
    Applicant: Verizon Patent and Licensing Inc.
    Inventors: Randolph Torres, Ashuma Singh Kaul, Todd K. Jones, Ravi K. Sharma, Peter D. Maxwell, Sandeep Juneja
  • Spirocycle compounds and methods of making and using same
    Patent number: 10781211
    Abstract: Provided herein are spirocycle compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: September 22, 2020
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Daniel J. Buzard, Michael B. Shaghafi, Justin S. Cisar, Cheryl A. Grice, Todd K. Jones, Olivia D. Weber
  • Pyrazole compounds and methods of making and using same
    Patent number: 10519134
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: December 31, 2019
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Olivia D. Weber, Michael B. Shaghafi, Cheryl A. Grice, Todd K. Jones
  • Radiolabeled monoacylglycerol lipase occupancy probe
    Patent number: 10463753
    Abstract: Provided herein are monoacylglycerol lipase (MGLL) occupancy probes comprising a MGLL inhibitor containing a positron emission tomography (PET) tracer radionuclide. Also provided are methods of assessing MGLL enzyme occupancy of a MGLL inhibitor using the radiolabeled occupancy probes described herein.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: November 5, 2019
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Cheryl A. Grice, Todd K. Jones, Justin S. Cisar, Iain Peter Fraser
  • Methods of treating inflammation or neuropathic pain
    Patent number: 10450302
    Abstract: Provided herein are methods of treating inflammation or neuropathic pain using an effective dose of a monoacylglycerol lipase inhibitor or a composition thereof.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: October 22, 2019
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Jacqueline Lorayne Blankman, Jason Robert Clapper, R. Alan B. Ezekowitz, Iain Peter Fraser, Cheryl A. Grice, Todd K. Jones, Gary Paul O'Neill, Archie Wayne Thurston, Jr., Channing Rodney Beals
  • Pyrazole compounds and methods of making and using same
    Patent number: 10385057
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or FAAH. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: August 20, 2019
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Cheryl A. Grice, Todd K. Jones, Katharine K. Duncan, Olivia D. Weber, Justin S. Cisar, Jeffrey E. Merit
  • Lp-PLA2 inhibitors
    Patent number: 10336709
    Abstract: Provided herein are lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitors, pharmaceutical compositions thereof, and methods of their use for the treatment of disease.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: July 2, 2019
    Assignee: ABIDE THERAPEUTICS, INC
    Inventors: Cheryl A. Grice, Micah Niphakis, Todd K. Jones
  • Pyrazole compounds and methods of making and using same
    Patent number: 10323038
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or FAAH. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: June 18, 2019
    Assignee: ABIDE THERAPEUTICS, INC.
    Inventors: Cheryl A. Grice, Todd K. Jones, Katharine K. Duncan, Justin S. Cisar, Jeffrey E. Merit, Olivia D. Weber
  • RADIOLABELED MONOACYLGLYCEROL LIPASE OCCUPANCY PROBE
    Publication number: 20190046668
    Abstract: Provided herein are monoacylglycerol lipase (MGLL) occupancy probes comprising a MGLL inhibitor containing a positron emission tomography (PET) tracer radionuclide. Also provided are methods of assessing MGLL enzyme occupancy of a MGLL inhibitor using the radiolabeled occupancy probes described herein.
    Type: Application
    Filed: February 17, 2017
    Publication date: February 14, 2019
    Inventors: Cheryl A Grice, Todd K Jones, Justin S Cisar, Iain Peter Fraser
  • Pyrazole compounds and methods of making and using same
    Patent number: 10093630
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of one or more of MAGL, ABHD6, and FAAH. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain, solid tumors and/or obesity.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: October 9, 2018
    Assignees: ABIDE THERAPEUTICS, INC., THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Dale L. Boger, Katerina Otrubova, Justin S. Cisar, Cheryl A. Grice, Todd K. Jones
  • Spirocycle compounds and methods of making and using same
    Patent number: 10030020
    Abstract: Provided herein are spirocycle compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: July 24, 2018
    Assignee: ABIDE THERAPEUTICS, INC.
    Inventors: Justin S. Cisar, Cheryl A. Grice, Todd K. Jones, Olivia D. Weber, Daniel J. Buzard, Michael B. Shaghafi
  • Piperazine carbamates and methods of making and using same
    Patent number: 9994537
    Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: June 12, 2018
    Assignee: ABIDE THERAPEUTICS, INC.
    Inventors: Justin S. Cisar, Cheryl A. Grice, Todd K. Jones, Olivia D. Weber, Dong-Hui Wang