Patents by Inventor Todd Koretke

Todd Koretke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyridines as DNMT1 inhibitors
    Patent number: 12285436
    Abstract: The invention relates to substituted pyridine derivatives that are inhibitors of the activity of DNA methyltransferase 1 (DNMT1). The invention also relates to pharmaceutical compositions comprising such compounds and methods of using such compounds in the treatment of cancer, pre-cancerous syndromes, beta haemoglobinopathy disorders, and other diseases associated with inappropriate DNMT1 activity.
    Type: Grant
    Filed: July 26, 2023
    Date of Patent: April 29, 2025
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Andrew B. Benowitz, David T. Fosbenner, Bryan Wayne King, Stuart Paul Romeril, Megan Ketchum, Todd Koretke, Elizabeth Ann Moroz, Grace Price