Abstract: Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.

Abstract: A garden edging connector includes an elongated member that has a first end, a second end and a perimeter wall having an outer surface. A longitudinal axis of the elongated member extends through the first and second ends. The elongated member has a central area and defining a first portion and a second portion of the elongated member with the first portion including the first end and the second portion including the second end. The outer surface has a plurality of teeth extending upwardly therefrom wherein each of the first and second portions includes some of the teeth. The teeth each have an upper edge being angled away from the central area and each of the teeth has inner edge directed toward the central area. A juncture of associated ones of the upper and inner edges forms a sharp edge to engage garden edging.

Abstract: A system and computerized method for managing faculty resources includes providing an input/output interface, a memory, and one or more processors communicably coupled to the input/output interface and the memory, providing a faculty database structure communicably coupled to the one or more processors and one or more databases, wherein the faculty database structure comprises a faculty profile for each faculty member that links personal data, position data, evaluation criteria and performance data together for the faculty member, selecting one or more of the faculty profiles using the input/output interface, determining a performance score for each selected faculty profile by comparing the performance data to the evaluation criteria using the one or more processors, and providing the performance score for each selected faculty profile to the input/output interface.