Patents by Inventor Todd Lenwell Randolph

Todd Lenwell Randolph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS FOR PREDICTING PRETERM BIRTH IN A PREGNANT FEMALE EXPOSED TO PROGESTOGENS
    Publication number: 20190369109
    Abstract: The present invention provides compositions and methods for predicting the probability of preterm birth in a pregnant female. The present invention provides a composition comprising one or more biomarkers selected from the biomarkers set forth in FIGS. 1, 3 through 12 and Tables 7 through 19, or optionally at least one pair of biomarkers selected from the biomarkers listed Tables 7 through 19, wherein the pair consists of one overexpressed and one underexpressed biomarker of the biomarkers set forth in Tables 7 through 19. In one embodiment, the invention provides a method of determining probability for preterm birth in a pregnant female, optionally in a pregnant female treated with a progestogen (e.g., 17-alpha hydroxyprogesterone caproate (17P)), the method comprising measuring in a biological sample obtained from the pregnant female one or biomarkers selected from the group consisting of one or more of the biomarkers of the invention.
    Type: Application
    Filed: December 21, 2018
    Publication date: December 5, 2019
    Inventors: John Jay Boniface, Julja Burchard, Gregory Charles Critchfield, Tracey Cristine Fleischer, Durlin Edward Hickok, Todd Lenwell Randolph, Babak Shahbaba
  • BIOMARKERS FOR PREDICTING PRETERM BIRTH IN A PREGNANT FEMALE EXPOSED TO PROGESTOGENS
    Publication number: 20180143202
    Abstract: The present invention provides compositions and methods for predicting the probability of preterm birth in a pregnant female. The present invention provides a composition comprising one or more biomarkers selected from the biomarkers set forth in FIGS. 1, 3 through 12 and Tables 7 through 19, or optionally at least one pair of biomarkers selected from the biomarkers listed Tables 7 through 19, wherein the pair consists of one overexpressed and one underexpressed biomarker of the biomarkers set forth in Tables 7 through 19. In one embodiment, the invention provides a method of determining probability for preterm birth in a pregnant female, optionally in a pregnant female treated with a progestogen (e.g., 17-alpha hydroxyprogesterone caproate (17P)), the method comprising measuring in a biological sample obtained from the pregnant female one or biomarkers selected from the group consisting of one or more of the biomarkers of the invention.
    Type: Application
    Filed: August 4, 2017
    Publication date: May 24, 2018
    Inventors: John Jay BONIFACE, Julja Burchard, Gregory Charles Critchfield, Tracey Cristine Fleischer, Durlin Edward Hickok, Todd Lenwell Randolph, Babak Shahbaba