Patents by Inventor Todd M. Vannelli

Todd M. Vannelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7229806
    Abstract: An in vivo method for the production of pHS via a recombinant host cell is disclosed. The host cell expresses at least one gene encoding a polypeptide having para-hydroxycinnamic acid decarboxylase activity in combination with either at least one gene encoding a polypeptide having tyrosine ammonia lyase activity or at least one gene encoding a polypeptide having phenylalanine ammonia lyase activity.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: June 12, 2007
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Arie Ben-Bassat, Wei Wei Qi, Fateme Sima Sariaslani, Xiao-Song Tang, Todd M. Vannelli
  • Patent number: 6951751
    Abstract: A novel tyrosine-inducible tyrosine ammonia lyase enzyme was isolated from the yeast Trichosporon cutaneum. This enzyme has a higher activity for tyrosine than for phenylalanine and is useful for the production of para-hydroxycinnamic acid directly from tyrosine. The gene encoding this enzyme was sequenced using 3? and 5? RACE cloning of the TAL cDNA and the gene was expressed in the yeast Saccharomyces cerevisiae and in the bacterium Escherichia coli.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: October 4, 2005
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Sabine Breinig, Wei Wei Qi, Fateme Sima Sariaslani, Todd M. Vannelli, Zhixiong Xue
  • Publication number: 20040023357
    Abstract: A novel tyrosine-inducible tyrosine ammonia lyase enzyme was isolated from the yeast Trichosporon cutaneum. This enzyme has a higher activity for tyrosine than for phenylalanine and is useful for the production of para-hydroxycinnamic acid directly from tyrosine. The gene encoding this enzyme was sequenced using 3′ and 5′ RACE cloning of the TAL cDNA and the gene was expressed in the yeast Saccharomyces cerevisiae and in the bacterium Escherichia coli.
    Type: Application
    Filed: May 16, 2003
    Publication date: February 5, 2004
    Inventors: Sabine Breinig, Wei Wei Qi, Fateme Sima Sariaslani, Todd M. Vannelli, Zhixiong Xue
  • Publication number: 20040018600
    Abstract: An in vivo method for the production of pHS via a recombinant host cell is disclosed. The host cell expresses at least one gene encoding a polypeptide having para-hydroxycinnamic acid decarboxylase activity in combination with either at least one gene encoding a polypeptide having tyrosine ammonia lyase activity or at least one gene encoding a polypeptide having phenylalanine ammonia lyase activity.
    Type: Application
    Filed: May 16, 2003
    Publication date: January 29, 2004
    Inventors: Arie Ben-Bassat, Wei Wei Qi, Fateme Sima Sariaslani, Xiao-Song Tang, Todd M. Vannelli