Patents by Inventor Todd O. McKinley

Todd O. McKinley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapy for post-traumatic osteoarthritis
    Patent number: 11565022
    Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: January 31, 2023
    Assignee: University of Iowa Research Foundation
    Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
  • Methods and systems for tissue damage identification and quantification
    Patent number: 11211166
    Abstract: Example embodiments are described that relate to the analysis of tissue damage in an injured patient. Example embodiments are methods and systems for collecting medical imaging data, identifying tissue damage in the medical imaging data, analyzing the tissue damage shown in the medical imaging data, and/or quantifying the tissue damage shown in the medical imaging data. The disclosed methods allow for determining a risk for multiple organ failure and systemic inflammation in a multiply injured patient.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: December 28, 2021
    Assignee: Indiana University Research & Technology Corp
    Inventors: Todd O. McKinley, Scott D. Steenburg
  • PREVENTATIVE THERAPY FOR POST-TRAUMATIC OSTEOARTHRITIS
    Publication number: 20210085827
    Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.
    Type: Application
    Filed: May 12, 2020
    Publication date: March 25, 2021
    Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
  • PREVENTATIVE THERAPY FOR POST-TRAUMATIC OSTEOARTHRITIS
    Publication number: 20200078491
    Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.
    Type: Application
    Filed: April 16, 2019
    Publication date: March 12, 2020
    Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
  • Preventative therapy for post-traumatic osteoarthritis
    Patent number: 10314941
    Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: June 11, 2019
    Assignee: University of Iowa Research Foundation
    Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
  • PREVENTATIVE THERAPY FOR POST-TRAUMATIC OSTEOARTHRITIS
    Publication number: 20180169298
    Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.
    Type: Application
    Filed: February 13, 2018
    Publication date: June 21, 2018
    Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
  • METHODS AND SYSTEMS FOR TISSUE DAMAGE IDENTIFICATION AND QUANTIFICATION
    Publication number: 20160078187
    Abstract: Example embodiments are described that relate to the analysis of tissue damage in an injured patient. Example embodiments are methods and systems for collecting medical imaging data, identifying tissue damage in the medical imaging data, analyzing the tissue damage shown in the medical imaging data, and/or quantifying the tissue damage shown in the medical imaging data. The disclosed methods allow for determining a risk for multiple organ failure and systemic inflammation in a multiply injured patient.
    Type: Application
    Filed: September 11, 2015
    Publication date: March 17, 2016
    Inventors: Todd O. McKinley, Scott D. Steenburg