Abstract: Methods of directly bonding a non-sliding archform to a patient's teeth are disclosed herein. An IDB tray with wells sized and shaped to form orthodontic brackets can be filled with a fluid, such as an adhesive or bonding agent. The IDB tray with the fluid-filled wells can be placed over the teeth of the patient. The fluid in the wells can contact the surfaces of the teeth. The fluid can be cured by way of exposure to UV light, forming orthodontic brackets and bonding the orthodontic brackets to the patient's teeth.

Abstract: A syringe includes a syringe body, a first plunger, a second plunger, and an inner tube. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger is disposed within the syringe cavity and defines a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The second plunger is disposed within the syringe cavity, the first plunger and the second plunger cooperatively defining a second chamber in the syringe cavity. The inner tube comprises an inner tube lumen, wherein the inner tube and a first plunger shaft lumen of a first plunger shaft define an annulus therebetween, the annulus in fluid communication with a first plunger channel of the first plunger and the annulus permits fluid communication between the syringe port and the first plunger channel.

Abstract: An indirect orthodontic bonding (IDB) tray preloaded with one or more orthodontic brackets with uncured pre-pasted adhesive. The loaded IDB tray can be produced by an IDB tray manufacturer and distributed to an orthodontist in a container that prevents the adhesive from curing. The loaded IDB tray can be removed from the container when the patient is ready for treatment. The loaded IDB tray can be placed over the dental arch of the patient such that the one or more orthodontic brackets can bond, via curing of the adhesive, to the teeth of the patient.

Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.

Abstract: A needleless connector includes a housing having a central longitudinal axis, a body portion, and a base portion. The body portion includes an inner surface forming an internal cavity, and a first port forming a first fluid passage to the housing cavity. The base portion includes a top end section and a bottom end section. The top end section has a protrusion, and the bottom end portion has a second port forming a second fluid passage to the housing cavity. The needleless connector further includes a valve having a wall with an inner surface forming a valve cavity. The valve is coupled with the housing such that the protrusion is positioned in the valve cavity, and a proximal end of the protrusion is spaced apart from a proximal end of the valve cavity.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a retention member. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member is coupled to the first plunger shaft, wherein the biasing member urges the first plunger to advance toward the syringe port. The retention mechanism prevents the biasing member from advancing the first plunger in an engaged position and permits the biasing member to advance the first plunger in a released position.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Abstract: A needleless connector includes a housing having a central longitudinal axis, a body portion, and a base portion. The body portion includes an inner surface forming an internal cavity, and a first port forming a first fluid passage to the housing cavity. The base portion includes a top end section and a bottom end section. The top end section has a protrusion, and the bottom end portion has a second port forming a second fluid passage to the housing cavity. The needleless connector further includes a valve having a wall with an inner surface forming a valve cavity. The valve is coupled with the housing such that the protrusion is positioned in the valve cavity, and a proximal end of the protrusion is spaced apart from a proximal end of the valve cavity.

Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.

Abstract: A needleless access connector having an access port and a sustained release antimicrobial coating only on a top surface of the access port is disclosed. The top surface of the access port can be defined by a top surface of a proximal end of a housing and a top surface of a head portion of a compressible valve disposed within an internal cavity of the housing. In certain embodiments of the present disclosure, the sustained release antimicrobial coating is on: (i) the top surface the proximal end of the housing, or (ii) the top surface of the head portion of the compressible valve, or (iii) the sustained release antimicrobial coating is only on both the top surface the proximal end of the housing and the top surface of the head portion of the compressible valve.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Abstract: A dual-chamber syringe may include an end wall and a primary plunger. The primary plunger may include a primary stopper. The primary stopper may form a primary chamber with the end wall. A secondary plunger may be in mechanical association with the primary plunger. The secondary plunger may include a secondary stopper. The secondary stopper may form a secondary chamber with the primary stopper. A primary nozzle may extend from the end wall and may be in fluid communication with the primary chamber. A secondary nozzle may extend from the end wall and may be in fluid communication with the secondary chamber.

Abstract: A valve including an antimicrobial agent can be used with needleless access connectors. The valve can have an insert that includes an antimicrobial coating thereon and/or the valve can have physical features, such as a series of tunnels or groves or a patterned surface, containing an antimicrobial formulation and/or the valve can be made of a material that includes an antimicrobial agent.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: A needleless access connector having an access port and a sustained release antimicrobial coating only on a top surface of the access port is disclosed. The top surface of the access port can be defined by a top surface of a proximal end of a housing and a top surface of a head portion of a compressible valve disposed within an internal cavity of the housing. In certain embodiments of the present disclosure, the sustained release antimicrobial coating is on: (i) the top surface the proximal end of the housing, or (ii) the top surface of the head portion of the compressible valve, or (iii) the sustained release antimicrobial coating is only on both the top surface the proximal end of the housing and the top surface of the head portion of the compressible valve.

Abstract: A valve including an antimicrobial agent can be used with needleless access connectors. The valve can have an insert that includes an antimicrobial coating thereon and/or the valve can have physical features, such as a series of tunnels or groves or a patterned surface, containing an antimicrobial formulation and/or the valve can be made of a material that includes an antimicrobial agent.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a dry disconnect shuttle valve comprising a male portion and a female portion, the dry disconnect shuttle valve configured for needleless use and maintaining a leak-free seal at disconnection with the at least one diluent port comprising the female portion of the dry disconnect shuttle valve.