Abstract: A multiple clip applier includes a handle portion and a pair of handles pivotably connected to opposite sides of the housing. A shaft extends from the housing and has a plurality of clips located within. A pair of opposed moveable jaws are attached to and extend from the distal end of the shaft. The jaws receive one of the clips serially when they are open and form the clip received serially when they close. A moveable forming mechanism is operatively connected to the handles by a pair of forming links. As the handles close, the forming mechanism closes the jaws to form the clip received therein, and as the handles are opened, the forming mechanism opens the jaws to receive another clip therein . A feeding mechanism is provided that has a moveable feed plate attached to the handles by a pair of feed links. The feed plate is releasably coupled to a clip pusher. As the handles are closed, the clip pusher remains stationary and uncoupled with the moving feed plate.