Patents by Inventor Todd Richard Elworthy

Todd Richard Elworthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-pyrrolidone derivatives as prostanoid agonists
    Patent number: 6849657
    Abstract: This invention relates to 8-aza prostanoid analogs which are generally EP4 receptor agonists and are represented by Formula I: wherein Q, B, X, J, Z, A and R1-R6 are as defined, their synthesis and use for treatment of osteoporosis and increasing bone density.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: February 1, 2005
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Todd Richard Elworthy, Michael Garret Roepel, David Bernard Smith
  • 2-Piperidone derivatives as prostaglandin agonists
    Publication number: 20040142969
    Abstract: The invention provides compounds of the Formula: 1
    Type: Application
    Filed: January 8, 2004
    Publication date: July 22, 2004
    Inventor: Todd Richard Elworthy
  • 8-Aza-11-deoxy prostaglandin analogues
    Publication number: 20030120079
    Abstract: This invention relates to compounds which are generally EP4 receptor agonists and which are represented by Formula I: 1
    Type: Application
    Filed: July 16, 2002
    Publication date: June 26, 2003
    Inventors: Todd Richard Elworthy, Tara Mirzadegan, Michael Garret Roepel, David Bernard Smith, Keith Adrian Walker
  • 2-pyrrolidone derivatives as prostanoid agonists
    Publication number: 20030064964
    Abstract: This invention relates to 8-aza prostanoid analogs which are generally EP4 receptor agonists and are represented by Formula I: 1
    Type: Application
    Filed: July 16, 2002
    Publication date: April 3, 2003
    Inventors: Todd Richard Elworthy, Michael Garret Roepel, David Bernard Smith
  • ?3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as .alpha..sub.1 -adrenoceptor antagonists
    Patent number: 5688795
    Abstract: The present invention relates to novel .alpha..sub.1 -adrenoceptor antagonists of Formula I: ##STR1## in which: p is 0 or 1;t is 0, 1 or 2;X is O, S or NR.sup.6 (in which R.sup.6 is hydro or (C.sub.1-6)alkyl);Y and Z are independently CH or N;R.sup.1 is hydro, hydroxy, halo, nitro, amino, cyano, (C.sub.1-4)alkylthio, acetylamino, trifluoroacetylamino, methylsulfonylamino, (C.sub.1-6)alkyl, (C.sub.3-6)cycloalkyl, (C.sub.3-6)cycloalkyl (C.sub.1-4)alkyl, oxazol-2-yl, aryl, heteroaryl, aryl (C.sub.1-4)alkyl, heteroaryl (C.sub.1-4)alkyl, (C.sub.1-6)alkyloxy, (C.sub.3-6)cycloalkyloxy, (C.sub.3-6)cycloalkyl (C.sub.1-4)alkyloxy, 2-propynyloxy, aryloxy, heteroaryloxy, aryl (C.sub.1-4)alkyloxy or heteroaryl (C.sub.1-4)alkyloxy (wherein alkyl is optionally substituted with one to three halo atoms and aryl or heteroaryl is optionally substituted with one to two substituents independently selected from halo and cyano);R.sup.2 is hydro, hydroxy, halo, cyano, (C.sub.1-6)alkyl or (C.sub.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: November 18, 1997
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Jurg Roland Pfister, David Ernest Clarke, Todd Richard Elworthy, David John Morgans, Jr., David Bruce Repke, Eric Brian Sjorgren, Helen Yen-hui Wu