Abstract: The present invention provides a switch suitable for efficient microfabric. The switch elements are disposed in several layers. Various embodiments provide various switching capabilities and operational characteristics. The switches can be protected by suitable packaging, and can be efficiently fabricated in groups or arrays.

Abstract: A long life balloon formed from a lamination. The lamination includes a polyester film with a total thickness of 4 ?m to 12 ?m. The polyester film includes a biaxially oriented polyester core layer and at least one amorphous copolyester skin layer. The lamination also includes a sealant layer and a gas barrier layer on an opposite side of the polyester film from the sealant layer. The oxygen transmission rate of the balloon is less than 0.1 cc/100 sqin/day, a bonding strength of the gas barrier layer to the surface of the polyester film is more than 300 g/in at dry conditions, a sealing strength of the balloon is more than 3.5 kg/in, and a floating time of the balloon is more than 20 days.

Abstract: The present invention relates to a method of treating an HIV-I infection with a compound according to formula I where R1, R2, R3, R4, R5, are as defined herein.

Abstract: An apparatus, comprising a plurality of closed cells disposed on a surface of a substrate. Each of the closed cells has at least one dimension that is less than about 1 millimeter and are configured to hold a medium therein. The apparatus also comprises a foam that contacts the closed cells. The foam has fluid walls that include a surfactant, and bubbles of the foam layer are filled with the medium.

Abstract: The present invention provides a switch suitable for efficient microfabrication. The switch elements are disposed in several layers. Various embodiments provide various switching capabilities and operational characteristics. The switches can be protected by suitable packaging, and can be efficiently fabricated in groups or arrays.

Abstract: An integrating impact switch that can discriminate between accelerations due to different stimuli is provided. Embodiments of the present invention actuate only in response to an acceleration whose magnitude is equal to or greater than an acceleration threshold for a predetermined continuous period of time. Embodiments of the present invention comprise an impact switch having a throw that is operatively coupled with a viscous damper that dampens motion of the throw. As a result, a stimulus that imparts an acceleration that meets or exceeds an acceleration threshold for a time period less than a predetermined time-period threshold does not actuate the switch. A stimulus that imparts an acceleration whose magnitude is equal to or greater than the acceleration threshold for a time period equal to the time-period threshold, however, does actuate the switch.

Abstract: A method of controlling the flow resistance of a fluid disposed on a surface of a substrate. The method comprises contacting a fluid with a plurality of cells on a substrate and adjusting amounts of a surfactant and a medium in the fluid to thereby form a foam layer contacting the walls of the cells. Each of the cells has at least one dimension that is less than about 1 millimeter and is configured to hold the medium therein. Each of the cells has walls that laterally enclose an area of a surface of the substrate and has a top opening. Bubbles of the foam layer have fluid walls that include a surfactant, are filled with the medium, and remain substantially stationary on the top openings of the cells for a period on average of at least about 1 minute.

Abstract: A long life balloon formed from a lamination. The lamination includes a polyester film with a total thickness of 4 ?m to 12 ?m. The polyester film includes a biaxially oriented polyester core layer and at least one amorphous copolyester skin layer. The lamination also includes a sealant layer and a gas barrier layer on an opposite side of the polyester film from the sealant layer. The oxygen transmission rate of the balloon is less than 0.1 cc/100 sqin/day, a bonding strength of the gas barrier layer to the surface of the polyester film is more than 300 g/in at dry conditions, a sealing strength of the balloon is more than 3.5 kg/in, and a floating time of the balloon is more than 20 days.

Abstract: The application discloses compounds of Formula I: wherein Q1, Q2, R1, R2, R3, and n are defined as described herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subject compounds.

Abstract: Disclosed is a method and system for integrating a plurality of isolated components to automatically provide real-time support to a participant in an online auction, particularly for live online auctions that may require quick decision making. An embodiment may automatically display information from the plurality of isolated components for the current item being auctioned in the online auction in a single user interface window. An embodiment may further update any information from any of the plurality of isolated components in real-time as the online auction is occurring. Examples of various isolated components that may be integrated into the single user interface window include: item history reports, third party valuation reports on the item, and the interface into the online auction. Various embodiments may have additional user interface windows concurrently monitoring/automatically integrating with different online auction locations that are concurrently auctioning different items.

Abstract: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.

Abstract: Heat sink comprising a base and a plurality of heat exchange elements. The elements are connected to and raised above, a surface of the base. There is a first row of the elements, with each of the elements having a long dimension that is substantially parallel to the long dimension of the other elements of the first row and to the surface. There is a second row of the elements, each of the elements having a long dimension that is substantially parallel to the long dimension of the other elements of the second row and to the surface. The first row and the second row are substantially opposed to each other such that one set of ends of the elements of the first row are staggered with respect to one set of ends of the elements of the second row.

Abstract: An apparatus comprising a heat sink and a plenum. The heat sink includes a base and a plurality of heat exchange elements, connected to and raised above, a surface of the base. The plenum is located above the heat exchange elements. The plenum includes a housing configured to hold a positive air-pressure therein, and openings in a surface of the housing. The opening are positioned such that air exiting the plenum through the openings is directed to the heat sink.

Abstract: A cooler block for an agricultural tractor comprising a cooler assembly mounted on a radiator and coupled to the radiator by upper and lower linkages. The cooler assembly can be moved between a first position in which the cooler assembly lies parallel to the radiator and a second position in which the cooler assembly is inclined relative to the radiator. The cooler assembly is pivotable about a pivot in the upper linkage that is itself movable relative to the radiator. The lower linkage allows the entire cooler assembly to rise and the pivot of the upper linkage to move away from the radiator as the cooler assembly is pivoted from the first to the second position. A detent is incorporated into one of the two linkages to retain the cooler assembly in the second position.

Abstract: An artificial insemination system and its use requires a sheath, a pumping device, and an AI gun-straw of semen assembly. As intended for the present invention, the AI gun-straw of semen assembly is insertable into the central lumen of the sheath. There, the distal end of the straw of semen is insertable into a slidable insert, which, in turn, is insertable into a transfer tunnel. Last, the transfer tunnel opens into an ejection port in the ventrodistal portion of the sheath. As further intended for the present invention, the pumping device is attachable to the proximal portion of the sheath for inflating a balloon on the distal portion of the sheath. The balloon, when expanded within the uterine body, anchors the ejection port within the uterine body during insemination.

Abstract: Device including channel having channel input and output. Channel has interior channel surface extending along channel path from channel input to output. In one implementation, channel includes plurality of channel sections in serial communication along channel path. Each of channel sections includes first internal circumference spaced apart along channel path from second internal circumference, in each of channel sections the first and second internal circumferences being substantially different. Each of channel sections includes sub-surface of interior channel surface. At least region of sub-surface of each channel section includes distribution of raised micro-scale features. As another implementation, at least first region of interior channel surface includes distribution of raised micro-scale features interrupted by plurality of raised barriers spaced apart along channel path on interior channel surface.

Abstract: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q1, R, and X are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.

Abstract: The present invention relates to a method of treating an HIV-I infection with a compound according to formula I where R1, R2, R3, R4, R5, are as defined herein.

Abstract: Compounds of the formula: wherein R1, R2, Ar1, Ar2, and n are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subject compounds.

Abstract: Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.