Patents by Inventor Todd Robert Ryder

Todd Robert Ryder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers
    Patent number: 6989448
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, asthma, amyotropic lateral sclerosis, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: January 24, 2006
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder, Anthony Denver Sercel, Yuntao Song
  • Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases
    Patent number: 6809119
    Abstract: The invention relates to BCAT inhibitors and the use thereof for treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome, treating or preventing the adverse consequences of the overstimulation of the excitatory amino acids, treating anxiety, psychosis, convulsions, aminoglycoside antibiotics-induced hearing loss, migraine headache, chronic pain, neuropathic pain, Parkinson's disease, diabetic retinopathy, glaucoma, CMV retinitis, urinary incontinence, opioid tolerance or withdrawal, and inducing anesthesia, as well as for enhancing cognition.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: October 26, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Lain-Yen Hu, Suzanne Ross Kesten, Huangshu Lei, Todd Robert Ryder, David Juergen Wustrow
  • Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases
    Publication number: 20030149110
    Abstract: The invention relates to BCAT inhibitors and the use thereof for treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome, treating or preventing the adverse consequences of the overstimulation of the excitatory amino acids, treating anxiety, psychosis, convulsions, aminoglycoside antibiotics-induced hearing loss, migraine headache, chronic pain, neuropathic pain, Parkinson's disease, diabetic retinopathy, glaucoma, CMV retinitis, urinary incontinence, opioid tolerance or withdrawal, and inducing anesthesia, as well as for enhancing cognition.
    Type: Application
    Filed: November 26, 2002
    Publication date: August 7, 2003
    Inventors: Lain-Yen Hu, Suzanne Ross Kesten, Huangshu Lei, Todd Robert Ryder, David Juergen Wustrow
  • Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers
    Publication number: 20030060419
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below.
    Type: Application
    Filed: September 25, 2002
    Publication date: March 27, 2003
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder, Anthony Denver Sercel, Yuntao Song
  • Calcium channel blockers
    Publication number: 20030060632
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below.
    Type: Application
    Filed: September 23, 2002
    Publication date: March 27, 2003
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder
  • Calcium channel blockers
    Patent number: 6495715
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: December 17, 2002
    Assignee: Warner-Lambert Company
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder
  • Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers
    Patent number: 6469038
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, asthma, amyotropic lateral sclerosis, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: October 22, 2002
    Assignee: Warner-Lambert Company
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder, Anthony Denver Sercel, Yuntao Song
  • Substituted diarylalkyl amides as calcium channel antagonists
    Patent number: 6458781
    Abstract: The present invention provides compounds that block calcium channels and have the Formula I: The present invention also provides pharmaceutical compositions containing the compounds of Formula I and methods of using them to treat stroke, cerebral ischemia, head trauma, and epilepsy.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: October 1, 2002
    Inventors: David Thomas Connor, Lain-Yen Hu, Thomas Charles Malone, Michael Francis Rafferty, Bruce David Roth, Todd Robert Ryder, Anthony Denver Sercel, Yuntao Song
  • Calcium channel blockers
    Publication number: 20010023249
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below.
    Type: Application
    Filed: January 25, 2001
    Publication date: September 20, 2001
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder
  • Heterocyclic substituted aniline calcium channel blockers
    Patent number: 6251919
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, epilepsy, asthma, amyotrophic lateral sclerosis, or pain and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: June 26, 2001
    Assignee: Warner-Lambert
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder
  • Aniline derivatives as calcium channel blockers
    Patent number: 6251918
    Abstract: The present invention provides compounds that block calcium channels having formula (I). The present invention also provides methods of using the compounds of formula (I) to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds of formula (I).
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: June 26, 2001
    Assignee: Warner-Lambert Company
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder
  • Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers
    Patent number: 6166052
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. ##STR1## The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, asthma, amyotropic lateral sclerosis, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: December 26, 2000
    Assignee: Warner-Lambert Company
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder, Anthony Denver Sercel, Yuntao Song
  • Substituted peptidylamine calcium channel blockers
    Patent number: 6117841
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. ##STR1## The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: September 12, 2000
    Assignee: Warner-Lambert Company
    Inventors: Lain-Yen Hu, Thomas Charles Malone, Laszlo Nadasdi, Michael Francis Rafferty, Todd Robert Ryder, Diego F. Silva, Yuntao Song, Balazs G. Szoke, Laszlo Urge