Patents by Inventor Todd S. Gac

Todd S. Gac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted cyclopentanes for inducing hair growth
    Patent number: 9499478
    Abstract: Provided herein, inter alia, are, methods of using esters of bimatoprost with the Formula (I):
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: November 22, 2016
    Assignee: ALLERGAN, INC.
    Inventors: David F. Woodward, Jenny W. Wang, Neil J. Poloso, Todd S. Gac, Robert M. Burk, Michael E. Garst
  • Compounds and methods for treating ocular diseases
    Patent number: 9340534
    Abstract: Described herein are compounds of formula I compositions and methods for the treatment of diseases affecting the eye, including glaucoma or ocular hypertension.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: May 17, 2016
    Assignee: ALLERGAN, INC.
    Inventors: Robert M. Burk, Todd S. Gac
  • Therapeutic cyclopentanols, compositions thereof, and methods for use thereof
    Patent number: 9315486
    Abstract: Described herein are well-defined cyclopentanols useful for treating glaucoma and ocular hypertension.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: April 19, 2016
    Assignee: ALLERGAN, INC.
    Inventors: Robert M. Burk, Todd S. Gac
  • COMPOUNDS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20160024068
    Abstract: Described herein are compounds of formula I compositions and methods for the treatment of diseases affecting the eye, including glaucoma or ocular hypertension.
    Type: Application
    Filed: July 27, 2015
    Publication date: January 28, 2016
    Inventors: Robert M. Burk, Todd S. Gac
  • THERAPEUTIC CYCLOPENTANOLS, COMPOSITIONS THEREOF, AND METHODS FOR USE THEREOF
    Publication number: 20150119454
    Abstract: Described herein are well-defined cyclopentanols useful for treating glaucoma and ocular hypertension.
    Type: Application
    Filed: October 29, 2014
    Publication date: April 30, 2015
    Inventors: Robert M. Burk, Todd S. Gac
  • Phosphate Esters of Bimatoprost and the Prostamides
    Publication number: 20150119367
    Abstract: Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.
    Type: Application
    Filed: October 29, 2013
    Publication date: April 30, 2015
    Applicant: Allergan, Inc.
    Inventors: David F. Woodward, Jenny W. Wang, Neil J. Poloso, Todd S. Gac, Robert M. Burk, Michael E. Garst
  • ESTER DERIVATIVES OF BIMATOPROST COMPOSITIONS AND METHODS
    Publication number: 20150005377
    Abstract: Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.
    Type: Application
    Filed: September 16, 2014
    Publication date: January 1, 2015
    Inventors: David F. Woodward, Jenny W. Wang, Neil J. Poloso, Todd S. Gac, Robert M. Burk, Michael E. Garst
  • Ester Derivatives of Bimatoprost Compositions and Methods
    Publication number: 20130324606
    Abstract: Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.
    Type: Application
    Filed: February 13, 2012
    Publication date: December 5, 2013
    Applicant: ALLERGAN, INC.
    Inventors: David F. Woodward, Jenny W. Wang, Neil J. Poloso, Todd S. Gac, Robert M. Burk, Michael E. Garst
  • Substituted cyclopentanes or cyclopentanones as therapeutic agents
    Patent number: 8541603
    Abstract: Therapeutic compounds, methods, and compositions are disclosed herein for treating glaucoma and baldness in mammals. The specific compounds are described herein and are modified prostaglandin derivates.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: September 24, 2013
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Todd S. Gac, Vinh X. Ngo
  • SUBSTITUTED CYCLOPENTANES OR CYCLOPENTANONES AS THERAPEUTIC AGENTS
    Publication number: 20110190301
    Abstract: Therapeutic compounds, methods, and compositions are disclosed herein for treating glaucoma and baldness in mammals. The specific compounds are described herein and are modified prostaglandin derivates.
    Type: Application
    Filed: May 13, 2009
    Publication date: August 4, 2011
    Applicant: ALLERGAN, INC.
    Inventors: David W. Old, Vinh X. Ngo, Todd S. Gac
  • THERAPEUTIC AGENTS FOR TREATMENT OF OCULAR HYPERTENSION
    Publication number: 20110184055
    Abstract: The invention provides well-defined amides for treating glaucoma and ocular hypertension.
    Type: Application
    Filed: January 21, 2011
    Publication date: July 28, 2011
    Applicant: ALLERGAN, INC.
    Inventors: David W. Old, Todd S. Gac
  • Therapeutic amides
    Patent number: 7985767
    Abstract: Compounds of the formula are disclosed herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: July 26, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Robert M. Burk, Todd S. Gac
  • Therapeutic compounds
    Patent number: 7897629
    Abstract: Disclosed herein is a compound having a structure or a pharmaceutically acceptable salt thereof, or a prodrug thereof. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: March 1, 2011
    Assignee: Allergan, Inc.
    Inventors: Robert M. Burk, David W. Old, Todd S. Gac
  • Substituted cyclopentanes or cyclopentanones as therapeutic agents
    Patent number: 7635716
    Abstract: Novel compounds, and therapeutic methods, compositions and medicament related thereto are disclosed herein.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: December 22, 2009
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Todd S. Gac, Vinh X. Ngo
  • Substituted cyclopentanes or cyclopentanones as therapeutic agents
    Patent number: 7405240
    Abstract: The compounds disclosed herein are useful for treating glaucoma, ocular hypertension, and baldness.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: July 29, 2008
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Todd S. Gac, Vinh X. Ngo
  • THERAPEUTIC AMIDES
    Publication number: 20080119539
    Abstract: Compounds of the formula are disclosed herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: September 6, 2007
    Publication date: May 22, 2008
    Inventors: David W. Old, Robert M. Burk, Todd S. Gac
  • Substituted cyclopentanes or cyclopentanones as therapeutic agents
    Patent number: 7323591
    Abstract: Therapeutic compounds, methods, and compositions are disclosed herein. These compounds have prostaglandin EP2 activity, and are useful to treat and/or prevent glaucoma and/or ocular hypertension in a mammal.
    Type: Grant
    Filed: January 4, 2007
    Date of Patent: January 29, 2008
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Todd S. Gac, Vinh X. Ngo
  • Prostanoic acid derivatives as agents for lowering intraocular pressure
    Patent number: 6670485
    Abstract: The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; wherein hatched lines represent the &agr; configuration, a triangle represents the &bgr; configuration and a dotted line represents the presence or absence of a double bond; A and B are CH2; D represents a covalent bond or CH2, O, S or NH; X is CO2R, CONR2, CH2OR, P(O)(OR)2, CONRSO2R SONR2 or Y is O, OH, OCOR2, halogen or cyano; Z is CH2 or a covalent bond; R is H or R2; R1 is H, R2, phenyl, or COR2; R2 is C1-C5 lower alkyl or alkenyl and R3 is benzothienyl, benzofuranyl, naphthyl or substituted derivatives thereof, wherein the substituents maybe selected from the group consisting of C1-C5 alkyl, halogen, CF3, CN, NO2, NR2, CO2R and OR.
    Type: Grant
    Filed: November 13, 2002
    Date of Patent: December 30, 2003
    Assignee: Allergan, Inc.
    Inventors: Robert M. Burk, Todd S. Gac
  • Prostanoic acid derivatives as agents for lowering intraocular pressure
    Publication number: 20030105155
    Abstract: The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; 1
    Type: Application
    Filed: November 13, 2002
    Publication date: June 5, 2003
    Applicant: Allergan Sales, Inc.
    Inventors: Robert M. Burk, Todd S. Gac
  • Prostanoic acid derivatives as agents for lowering intraocular pressure
    Patent number: 6531504
    Abstract: The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; wherein hatched lines represent the &agr; configuration, a triangle represents the &bgr; configuration and a dotted line represents the presence or absence of a double bond; A and B are CH2; D represents a covalent bond or CH2, O, S or NH; X is CO2R, CONR2, CH2OR, P(O)(OR)2, CONRSO2R SONR2 or Y is O, OH, OCOR2, halogen or cyano; Z is CH2 or a covalent bond; R is H or R2; R1 is H, R2, phenyl, or COR2; R2 is C1-C5 lower alkyl or alkenyl and R3 is benzothienyl, benzofuranyl, naphthyl or substituted derivatives thereof, wherein the substituents maybe selected from the group consisting of C1-C5 alkyl, halogen, CF3, CN, NO2, NR2, CO2R and OR.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: March 11, 2003
    Assignee: Allergan, Inc.
    Inventors: Robert M. Burk, Todd S. Gac