Patents by Inventor Todd S. McDermott

Todd S. McDermott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF (2S,5R)-5-ETHYNYL-1-PYRROLIDINE-2-CARBONITRILE
    Publication number: 20160152600
    Abstract: A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
    Type: Application
    Filed: January 18, 2016
    Publication date: June 2, 2016
    Inventors: Todd S. McDermott, Seble H. Wagaw, Kenneth M. Engstrom, Jorge Gandarilla, Albert Kruger, Michael J. Rozema, Michael G. Fickes, Steven J. Wittenberger, Lakshmi Bhagavatula, Thomas B. Borchardt
  • Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
    Patent number: 9260411
    Abstract: A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: February 16, 2016
    Assignee: AbbVie Inc.
    Inventors: Todd S. McDermott, Seble H. Wagaw, Kenneth M. Engstrom, Jorge Gandarilla, Albert Kruger, Michael J. Rozema, Michael G. Fickes, Steven J. Wittenberger, Lakshmi Bhagavatula, Thomas B. Borchardt
  • Tablet Dosage Forms
    Publication number: 20140234415
    Abstract: The present invention features tablet dosage forms comprising two or more different active ingredients. In one embodiment, a tablet dosage form of the invention comprises a first layer and a second layer, wherein the first layer comprises polymer-based solid dispersion particles having a mean particle size of no more than 200 ?m.
    Type: Application
    Filed: February 19, 2014
    Publication date: August 21, 2014
    Inventors: Todd S. McDermott, Peter T. Mayer, Benjamin M. Collman, Weili Wang, Bei Chen
  • Process for the preparation of farnesyltransferase inhibitors
    Patent number: 6248919
    Abstract: A process for the preparation of preparation of farnesyltransferase inhibitors of formula (I) or pharmaceutically acceptable salts or prodrugs thereof, is disclosed.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: June 19, 2001
    Assignee: Abbott Laboratories
    Inventors: Todd S. McDermott, Anne E. Bailey, Ramiya Premchandran, Lakshima Bhagavatula