Patents by Inventor Todd W. Seeley

Todd W. Seeley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced erythropoiesis and iron metabolism
    Patent number: 8604012
    Abstract: The present invention relates to methods and compounds for increasing serum iron in a subject.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: December 10, 2013
    Assignee: Fibrogen, Inc.
    Inventors: Stephen J. Klaus, Christopher J. Molineaux, Thomas B. Neff, Volkmar Guenzler-Pukall, Ingrid Langsetmo Parobok, Todd W. Seeley, Robert C. Stephenson
  • Compounds and methods for treatment of cancer
    Patent number: 8530404
    Abstract: The invention relates to methods and compounds for treating or preventing cancer. Methods for treating or preventing cancer, for inhibiting tumor growth, reducing tumor volume, inhibiting tumor progression, inhibiting metastasis, and improving survival are provided herein.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: September 10, 2013
    Assignee: FibroGen, Inc.
    Inventors: Todd W. Seeley, David Y. Liu, Stephen J. Klaus
  • CONNECTIVE TISSUE GROWTH FACTOR ANTISENSE OLIGONUCLEOTIDES
    Publication number: 20130178510
    Abstract: The present invention relates to antisense oligonucleotides that target human CTGF mRNA and inhibit CTGF mRNA expression. Additionally, regions of human CTGF mRNA that are exceptionally sensitive to antisense inhibition are disclosed. Pharmaceutical compositions comprising the antisense oligonucleotides are further disclosed. These compositions are useful for treating disorders and conditions that are associated with or influenced by CTGF expression.
    Type: Application
    Filed: July 11, 2012
    Publication date: July 11, 2013
    Applicant: FibroGen, Inc.
    Inventors: Mark D. Sternlicht, Todd W. Seeley
  • Fat regulation
    Patent number: 8202834
    Abstract: The present invention provides methods and compounds for regulating fat metabolism and achieving fat homeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e.g., obesity, diabetes, atherosclerosis, etc.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: June 19, 2012
    Assignee: FibroGen, Inc.
    Inventors: Patrick D. Fourney, Volkmar Guenzler-Pukall, Stephen J. Klaus, Al Y. Lin, Thomas B. Neff, Todd W. Seeley
  • Treatment of diabetes
    Patent number: 8124582
    Abstract: The present invention relates to methods and compounds for regulating glucose metabolism, achieving glucose homeostasis, and decreasing blood glucose levels. Methods and compounds for treating or preventing diabetes, hyperglycemia, and disorders and conditions associated with altered or impaired glucose metabolism are also provided.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: February 28, 2012
    Assignee: FibroGen, Inc.
    Inventors: Volkmar Guenzler-Pukall, Stephen J. Klaus, Ingrid Langsetmo Parobok, Todd W. Seeley
  • Enhanced erythropoiesis and iron metabolism
    Publication number: 20110038950
    Abstract: The present invention relates to methods and compounds for regulating or enhancing erythropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
    Type: Application
    Filed: July 12, 2010
    Publication date: February 17, 2011
    Inventors: Stephen J. Klaus, Christopher J. Molineaux, Thomas B. Neff, Volkmar Guenzler-Pukall, Ingrid Langsetmo Parobok, Todd W. Seeley, Robert C. Stephenson
  • Enhanced erythropoiesis and iron metabolism
    Publication number: 20110039886
    Abstract: The present invention relates to methods and compounds for regulating or enhancing erthropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
    Type: Application
    Filed: July 12, 2010
    Publication date: February 17, 2011
    Inventors: Stephen J. Klaus, Christopher J. Molineaux, Thomas B. Neff, Volkmar Guenzler-Pukall, Ingrid Langsetmo Parobok, Todd W. Seeley, Robert C. Stephenson
  • Compounds and methods for treatment of cancer-related anemia
    Publication number: 20110015223
    Abstract: The invention relates to methods and compounds for treating anemia of cancer. In particular, methods for treating anemia of cancer in a subject having cancer, and methods for increasing reticulocytes, increasing hemoglobin, increasing hematocrit, and increasing red blood cell count in subjects having anemia of cancer, wherein such subjects are refractory to treatment with recombinant human erythropoietin (EPO) are encompassed herein.
    Type: Application
    Filed: August 16, 2010
    Publication date: January 20, 2011
    Applicant: FibroGen, Inc.
    Inventors: Todd W. Seeley, David Y. Liu, Stephen J. Klaus
  • Enhanced erythropoiesis and iron metabolism
    Publication number: 20100278941
    Abstract: The present invention relates to methods and compounds for regulating or enhancing erthropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
    Type: Application
    Filed: July 12, 2010
    Publication date: November 4, 2010
    Inventors: Stephen J. Klaus, Christopher J. Molineaux, Thomas B. Neff, Volkmar Guenzler-Pukall, Ingrid Langsetmo Parobok, Todd W. Seeley, Robert C. Stephenson
  • Enhanced erythropoiesis and iron metabolism
    Publication number: 20100280044
    Abstract: The present invention relates to methods and compounds for regulating or enhancing erthropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
    Type: Application
    Filed: July 12, 2010
    Publication date: November 4, 2010
    Inventors: Stephen J. Klaus, Christopher J. Molineaux, Thomas B. Neff, Volkmar Guenzler-Pukall, Ingrid Langsetmo Parobok, Todd W. Seeley, Robert C. Stephenson
  • Compounds and methods for treatment of chemotherapy-induced anemia
    Publication number: 20100204269
    Abstract: The invention relates to methods and compounds for treating chemotherapy-induced anemia. In particular, methods for treating chemotherapy-induced anemia in subjects refractory to treatment with recombinant human erythropoietin are encompassed herein.
    Type: Application
    Filed: April 13, 2010
    Publication date: August 12, 2010
    Applicant: FibroGen, Inc.
    Inventors: Todd W. Seeley, David Y. Liu, Stephen J. Klaus
  • Fat regulation
    Publication number: 20100168152
    Abstract: The present invention provides methods and compounds for regulating fat metabolism and achieving fat homeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e.g., obesity, diabetes, atherosclerosis, etc.
    Type: Application
    Filed: October 19, 2009
    Publication date: July 1, 2010
    Applicant: FibroGen, Inc.
    Inventors: Patrick D. Fourney, Volkmar Guenzler-Pukall, Stephen J. Klaus, Al Y. Lin, Thomas B. Neff, Todd W. Seeley
  • Compounds and methods for treatment of chemotherapy-induced anemia
    Patent number: 7713986
    Abstract: The invention relates to methods and compounds for treating chemotherapy-induced anemia. In particular, methods for treating chemotherapy-induced anemia in subjects refractory to treatment with recombinant human erythropoietin are encompassed herein.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: May 11, 2010
    Assignee: FibroGen, Inc.
    Inventors: Todd W. Seeley, David Y. Liu, Stephen J. Klaus
  • Fat regulation
    Patent number: 7618940
    Abstract: The present invention provides methods and compounds for regulating fat metabolism and achieving fat homoeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e.g., obesity, diabetes, atherosclerosis, etc.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: November 17, 2009
    Assignee: FibroGen, Inc.
    Inventors: Patrick D. Fourney, Volkmar Guenzler-Pukall, Stephen J. Klaus, Al Y. Lin, Thomas B. Neff, Todd W. Seeley
  • Compounds and methods for treatment of chemotherapy-induced anemia
    Publication number: 20070292433
    Abstract: The invention relates to methods and compounds for treating chemotherapy-induced anemia. In particular, methods for treating chemotherapy-induced anemia in subjects refractory to treatment with recombinant human erythropoietin are encompassed herein.
    Type: Application
    Filed: June 15, 2006
    Publication date: December 20, 2007
    Applicant: FibroGen, Inc.
    Inventors: Todd W. Seeley, David Y. Liu, Stephen J. Klaus
  • Compounds and methods for treatment of cancer-related anemia
    Publication number: 20070293575
    Abstract: The invention relates to methods and compounds for treating anemia of cancer. In particular, methods for treating anemia of cancer in a subject having cancer, and methods for increasing reticulocytes, increasing hemoglobin, increasing hematocrit, and increasing red blood cell count in subjects having anemia of cancer, wherein such subjects are refractory to treatment with recombinant human erythropoietin (EPO) are encompassed herein.
    Type: Application
    Filed: June 15, 2006
    Publication date: December 20, 2007
    Applicant: FibroGen, Inc.
    Inventors: Todd W. Seeley, David Y. Liu, Stephen J. Klaus
  • Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers
    Patent number: 6974867
    Abstract: Inhibitors of KIAA0175 are provided that reduce the expression or biological activities of KIAA0175, p53 and/or p21 in a mammalian cell. KIAA0175 inhibitors include anti-sense molecules, ribozymes, antibodies and antibody fragments, proteins and polypeptides as well as small molecules. KIAA0175 inhibitors find use in compositions and methods for decreasing KIAA0175, p53 and/or p21 gene expression as well as methods for increasing the chemo and/or radiosensitivity of mammalian cells, including tumor cells, methods for decreasing the side effects of cancer therapy and methods for treating neoplastic diseases.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: December 13, 2005
    Assignee: Chiron Corporation
    Inventors: Bin Wu, Todd W. Seeley, Lewis T. Williams
  • Fat regulation
    Publication number: 20040235082
    Abstract: The present invention provides methods and compounds for regulating fat metabolism and achieving fat homoeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e.g., obesity, diabetes, atherosclerosis, etc.
    Type: Application
    Filed: December 4, 2003
    Publication date: November 25, 2004
    Inventors: Patrick D. Fourney, Volkmar Guenzler-Pukall, Stephen J. Klaus, Al Y. Lin, Thomas B. Neff, Todd W. Seeley
  • Treatment of diabetes
    Publication number: 20040204356
    Abstract: The present invention relates to methods and compounds for regulating glucose metabolism, achieving glucose homeostasis, and decreasing blood glucose levels. Methods and compounds for treating or preventing diabetes, hyperglycemia, and disorders and conditions associated with altered or impaired glucose metabolism are also provided.
    Type: Application
    Filed: December 4, 2003
    Publication date: October 14, 2004
    Inventors: Volkmar Guenzler-Pukall, Stephen J. Klaus, Ingrid Langsetmo Parobok, Todd W. Seeley
  • Bovine collagens and gelatins
    Publication number: 20040018592
    Abstract: The present invention provides animal collagens and gelatins and compositions thereof, and methods of producing the same.
    Type: Application
    Filed: March 26, 2003
    Publication date: January 29, 2004
    Applicant: FibroGen, Inc.
    Inventors: Marcum P. Bell, Thomas B. Neff, James W. Polarek, Todd W. Seeley