Abstract: Embodiments described herein provide for training an artificial intelligence model to boost dose depositions. The artificial intelligence model receives medical images and a dose deposition determined according to a first dose deposition model. The artificial intelligence model modifies the received dose deposition determined according to the first dose deposition model such that the dose deposition simulates a dose deposition determined by a second dose deposition model.

Abstract: Embodiments described herein provide for coupling Monte Carlo source modeling with deterministic dose calculations. An internal volumetric first scatter distributed source of a patient is determined using Monte Carlo simulations and ingested into one or more dosing algorithms. The dosing algorithms use the source model to determine a dose deposition.

Abstract: In accordance with at least some embodiments of the present disclosure, a process to estimate scattered radiation contained in x-ray projections for computed tomography (CT) reconstruction is provided. The process may construct an object model based on a plurality of projection images generated by CT scanning of an object using an x-ray radiation source and a detector panel. The process may construct a virtual radiation source based on the x-ray radiation source, and a virtual detector panel based on the detector panel. The process may perform a simulated CT scanning of the object model by simulating macroscopic behavior of particles being emitted from the virtual radiation source, passing through the object model, and being detected by the virtual detector panel. And the process may generate a simulated scatter image based on a first subset of particles scattered during the simulated CT scanning of the object model.

Abstract: In accordance with at least some embodiments of the present disclosure, a process to estimate scattered radiation contained in x-ray projections for computed tomography (CT) reconstruction is provided. The process may construct an object model based on a plurality of projection images generated by CT scanning of an object using an x-ray radiation source and a detector panel. The process may construct a virtual radiation source based on the x-ray radiation source, and a virtual detector panel based on the detector panel. The process may perform a simulated CT scanning of the object model by simulating macroscopic behavior of particles being emitted from the virtual radiation source, passing through the object model, and being detected by the virtual detector panel. And the process may generate a simulated scatter image based on a first subset of particles scattered during the simulated CT scanning of the object model.

Abstract: Various embodiments of the present invention provide processes for applying deterministic radiation transport solution methods for calculating doses and predicting scatter in radiotherapy and imaging applications. One method embodiment of the present invention is a process for using deterministic methods to calculate dose distributions resulting from radiotherapy treatments, diagnostic imaging, or industrial sterilization, and for calculating image scatter for the purposes of image reconstruction. In one embodiment of the present invention, a method provides a means for transport of external radiation sources through field-shaping devices. In another embodiment of the present invention, a method includes a process for calculating the dose response at selected points and volumes prior to radiotherapy treatment planning.

Abstract: Method and system that allows patient dose response functions to be calculated, prior to treatment planning, for external photon beam radiotherapy. In one embodiment, for each location where a separate dose value is desired, referred to as a dose region, adjoint calculations are performed to calculate the adjoint solution fields associated with that dose region. Once potential beam directions are specified, a ray tracing process is performed to transport the adjoint solution fields out of the patient and to locations where treatment plan parameters may be specified. The output of this process is the dose response at each dose region resulting from a prescribed photon fluence, at a given location, direction, and energy.

Abstract: One method embodiment of the present invention is a process for using deterministic methods to calculate dose distributions resulting from radiotherapy treatments, diagnostic imaging, or industrial sterilization, and for calculating scatter corrections used for image reconstruction. In one embodiment of the present invention, the method provides a means for constructing a deterministic computational grid from an acquired 3-D image representation, transport of an external radiation source through field shaping devices and into the computational grid, calculation of the radiation scatter and/or delivered dose in the computational grid, and subsequent transport of the scattered radiation to detectors external to the computational grid.