Abstract: A method and device for carrying out a chemical reaction, by supplying to the chemical reaction energy from an electron- and, optionally, photon-containing energy wave that is induced in one or more aggregated molecular ensembles, wherein the emission of which is stimulated from the ensembles. Emission is stimulated from the ensembles by a wide variety of energy inputs, and energy derived from this electron and/or photon energy wave is advantageously used as an energy source to assist chemical reduction reactions.

Abstract: A method and device for carrying out a chemical reaction, by supplying to the chemical reaction energy from an electron- and, optionally, photon-containing energy wave that is induced in one or more aggregated molecular ensembles, wherein the emission of which is stimulated from the ensembles. Emission is stimulated from the ensembles by a wide variety of energy inputs, and energy derived from this electron and/or photon energy wave is advantageously used as an energy source to assist chemical reduction reactions.

Abstract: A method and device for carrying out a chemical reaction, by supplying to the chemical reaction energy from an electron- and, optionally, photon-containing energy wave that is induced in one or more aggregated molecular ensembles, wherein the emission of which is stimulated from the ensembles. Emission is stimulated from the ensembles by a wide variety of energy inputs, and energy derived from this electron and/or photon energy wave is advantageously used as an energy source to assist chemical reduction reactions.

Abstract: An energy conversion device comprises an apparatus and a method for employing energy from an electron- and, optionally, photon-containing energy wave that is induced in one or more aggregated molecular ensembles. Emission is stimulated from the ensembles by a wide variety of energy inputs, and energy derived from this electron and/or photon energy wave is useful for modulation of signals in circuits; performing chemical reduction reactions; and performing as an energy conversion device, e.g., as a photovoltaic energy converter. Although differing from a laser by virtue its production of, inter alia, a charge transfer rather than merely light, the device of the invention can be employed in virtually all of the same fields in which a laser is utilized.

Abstract: An energy conversion device comprises an apparatus and a method for employing energy from an electron- and, optionally, photon-containing energy wave that is induced in one or more aggregated molecular ensembles. Emission is stimulated from the ensembles by a wide variety of energy inputs, and energy derived from this electron and/or photon energy wave is useful for modulation of signals in circuits; performing chemical reduction reactions; and performing as an energy conversion device, e.g., as a photovoltaic energy converter. Although differing from a laser by virtue its production of, inter alia, a charge transfer rather than merely light, the device of the invention can be employed in virtually all of the same fields in which a laser is utilized.

Abstract: This invention provides methods for selectively antagonizing the ?4?1 integrin heterodimer in a subject in need thereof, and preferably in a human subject. The methods of the invention utilize conjugates comprising two or more ?4?1 small molecule antagonists covalently attached to a biocompatible polymer. These methods of selectively inhibiting ?4?1 may be used modulate both normal and pathological biological processes mediated at least in part through ?4?1 activity.

Abstract: Methods are provided for using methotrexate (MTX) active agents in which reduced host toxicity is observed. Aspects of the methods include administering to a subject an effective amount of an MTX active agent in conjunction with a MTX toxicity-reducing adjuvant, such as a 2,2?-anhydropyrimidine, a derivative thereof or a uridine phosphorylase inhibitor. Also provided are compositions and kits that find use in practicing embodiments of the invention. The methods and compositions find use in a variety of applications, including the treatment of a variety of different disease conditions.

Abstract: YIGSR peptidomimetics and methods for making and using the same are provided. The subject YIGSR peptidomimetics are non-peptidic, biodegradation-resistant molecules that mimic the pentapeptide tyrosine-isoleucine-glycine-serine-arginine (YIGSR) binding site for the 67 kiloDalton (kDa) laminin binding protein (LBP). The subject peptidomimetics include a rigid or substantially rigid non-peptidic scaffold that effectively presents or positions a tyrosine or tyrosine-like group, an isoleucine or isoleucine-like group, a serine or serine-like group, and an arginine or arginine-like group in substantially the same manner as occurs in the YIGSR peptide itself. The subject peptidomimetics find use in a variety of different applications, including diagnostic and therapeutic applications.