Patents by Inventor Todd Yeates

Todd Yeates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220062430
    Abstract: Disclosed herein are self-assembling protein nanoparticles comprising passenger molecules of interest.
    Type: Application
    Filed: August 25, 2020
    Publication date: March 3, 2022
    Inventors: Todd Yeates, Yen-Ting Lai, Justin Miller, Phillip Nguyen, Yashes Srinivasan, Nithin Dharmaraj, Scott Taylor, Andrew Liu
  • Patent number: 8969521
    Abstract: Methods and systems for computationally designing self-assembling polypeptides are disclosed. A representation of a docked configuration of a symmetric protein architecture can be determined by a computing device configured to computationally symmetrically dock representations of protein building blocks within a representation of a symmetric protein architecture, where symmetrically docking a representation of a particular protein building block can include determining a configuration of the protein building blocks in three-dimensional space within the symmetric protein architecture configured to generate interfaces between building blocks suitable for computational protein interface design. The amino acid sequence of the docked protein building blocks can be computationally modified to specify protein-protein interfaces between the plurality of protein building blocks that are energetically favorable to drive self-assembly of a protein that includes the modified amino acid sequence.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: March 3, 2015
    Assignee: University of Washington Through its Center for Commercialization
    Inventors: David Baker, Neil King, William Sheffler, Todd Yeates
  • Publication number: 20130274441
    Abstract: Methods and systems for computationally designing self-assembling polypeptides are disclosed. A representation of a docked configuration of a symmetric protein architecture can be determined by a computing device configured to computationally symmetrically dock representations of protein building blocks within a representation of a symmetric protein architecture, where symmetrically docking a representation of a particular protein building block can include determining a configuration of the protein building blocks in three-dimensional space within the symmetric protein architecture configured to generate interfaces between building blocks suitable for computational protein interface design. The amino acid sequence of the docked protein building blocks can be computationally modified to specify protein-protein interfaces between the plurality of protein building blocks that are energetically favorable to drive self-assembly of a protein that includes the modified amino acid sequence.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 17, 2013
    Applicants: The Regents of the University of California, University of Washington through its Center for Commercialization
    Inventors: David Baker, Neil King, William Sheffler, Todd Yeates
  • Publication number: 20070218547
    Abstract: Self-assembling fusion proteins and nucleic acids encoding the same are provided. The subject fusion proteins include a first dimer forming oligomerization domain and a second tetramer forming oligomerization domain rigidly linked to each other. Also provided are regular structures made up of a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of self-assembled nanostructures, e.g., two-dimensional layers and three-dimensional networks, which structures find use in a variety of different applications.
    Type: Application
    Filed: March 31, 2004
    Publication date: September 20, 2007
    Inventors: Todd Yeates, Jennifer Padilla, Stephanie Yoshida, Chris Colovos