Patents by Inventor Tohru DAIRI

Tohru DAIRI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICROORGANISM PRODUCING EICOSAPENTAENOIC ACID AND METHOD FOR PRODUCING EICOSAPENTAENOIC ACID
    Publication number: 20230235271
    Abstract: An object of the present invention is to provide a microorganism that efficiently produces EPA and a method for producing EPA using the microorganism. The present invention relates to a microorganism having an ability to produce docosahexaenoic acid (DHA), wherein the microorganism contains a protein composed of an amino acid sequence in which at least one of the amino acid residues at positions 6, 65, 230, 231, and 275 in the amino acid sequence represented by SEQ ID NO: 2 has been substituted with another amino acid residue (mutated OrfB), and is capable of producing eicosapentaenoic acid (EPA), and the like.
    Type: Application
    Filed: February 15, 2023
    Publication date: July 27, 2023
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Tohru DAIRI, Yasuharu SATOH, Shohei HAYASHI, Mai NAKA, Tetsuro UJIHARA
  • Microorganism producing eicosapentaenoic acid and method for producing eicosapentaenoic acid
    Patent number: 11613728
    Abstract: An object of the present invention is to provide a microorganism that efficiently produces EPA and a method for producing EPA using the microorganism. The present invention relates to a microorganism having an ability to produce docosahexaenoic acid (DHA), wherein the microorganism contains a protein composed of an amino acid sequence in which at least one of the amino acid residues at positions 6, 65, 230, 231, and 275 in the amino acid sequence represented by SEQ ID NO: 2 has been substituted with another amino acid residue (mutated OrfB), and is capable of producing eicosapentaenoic acid (EPA), and the like.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: March 28, 2023
    Assignee: KYOWA HAKKO BIO CO., LTD.
    Inventors: Tohru Dairi, Yasuharu Satoh, Shohei Hayashi, Mai Naka, Tetsuro Ujihara
  • MICROORGANISM PRODUCING EICOSAPENTAENOIC ACID AND METHOD FOR PRODUCING EICOSAPENTAENOIC ACID
    Publication number: 20210309960
    Abstract: An object of the present invention is to provide a microorganism that efficiently produces EPA and a method for producing EPA using the microorganism. The present invention relates to a microorganism having an ability to produce docosahexaenoic acid (DHA), wherein the microorganism contains a protein composed of an amino acid sequence in which at least one of the amino acid residues at positions 6, 65, 230, 231, and 275 in the amino acid sequence represented by SEQ ID NO: 2 has been substituted with another amino acid residue (mutated OrfB), and is capable of producing eicosapentaenoic acid (EPA), and the like.
    Type: Application
    Filed: August 9, 2019
    Publication date: October 7, 2021
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Tohru DAIRI, Yasuharu SATOH, Shohei HAYASHI, Mai NAKA, Tetsuro UJIHARA
  • MICROORGANISM PRODUCING POLYUNSATURATED FATTY ACID AND METHOD FOR PRODUCING POLYUNSATURATED FATTY ACID
    Publication number: 20210309987
    Abstract: An object of the present invention is to provide a microorganism that efficiently produces a PUFA and a method for producing a PUFA using the microorganism. The present invention relates to a microorganism capable of producing a polyunsaturated fatty acid (PUFA), in which a gene encoding an exogenous polyketide synthase dehydratase (PS-DH) domain having a higher activity against 3-hydroxyhexanoyl acyl carrier protein (3-hydroxyhexanoyl ACP) than an endogenous FabA-like ?-hydroxyacyl-ACP dehydratase (FabA-DH) domain has been introduced into a microorganism having a PUFA metabolic pathway, and the like.
    Type: Application
    Filed: August 9, 2019
    Publication date: October 7, 2021
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Tohru DAIRI, Yasuharu SATOH, Shohei HAYASHI, Yasushi OGASAWARA, Tetsuro UJIHARA