Abstract: The present invention addresses the problem of providing an exceptional GLP-1 secretagogue that is a component derived from milk, a composition for promoting GLP-1 secretion, and a food/beverage or drug containing the same. Any selected from the group consisting of micellar casein, a hydrolysate thereof, a fraction thereof, a purified product thereof, and peptides including an amino acid sequence indicated by any of SEQ ID NOS.: 1-7 is configured as an active ingredient of a GLP-1 secretagogue and a composition for promoting GLP-1 secretion.

Abstract: An object of the present invention is to provide a GLP-1 secretagogue which is an incretin hormone-related drug relatively inexpensive, excellent in safety, and capable of promoting GLP-1 secretion without containing sucrose as an essential constituent. The object is achieved by a GLP-1 secretagogue characterized by containing D-psicose as an active ingredient.

Abstract: A method is provided to promote secretion of cholecystokinin (CCK) by administering an active component. The active component includes acrylic acid and/or an unsaturated aldehyde having a main chain of 4 to 12 carbon atoms having a double bond in at least position 2 or 4, where the main chain has 4 to 9 carbon atoms when there is a double bond in only position 2, and the main chain has 9 to 12 carbon atoms when there is a double bond in only position 4. The cholecystokinin secretion-promoting composition can be used as an appetite suppressant. By adding this cholecystokinin secretion-promoting composition to food, appetite-suppressing food products can be provided.

Abstract: A method is provided to promote secretion of cholecystokinin (CCK) by administering an active component. The active component includes acrylic acid and/or an unsaturated aldehyde having a main chain of 4 to 12 carbon atoms having a double bond in at least position 2 or 4, where the main chain has 4 to 9 carbon atoms when there is a double bond in only position 2, and the main chain has 9 to 12 carbon atoms when there is a double bond in only position 4. The cholecystokinin secretion-promoting composition can be used as an appetite suppressant. By adding this cholecystokinin secretion-promoting composition to food, appetite-suppressing food products can be provided.

Abstract: A CCK secretion-promoting substance and a use thereof are provided. This cholecystokinin secretion-promoting composition contains, as an active component, acrylic acid and/or an unsaturated aldehyde having a main chain of 4-12 carbon atoms having a double bond in at least position 2 or 4, wherein the main chain has 4-9 carbon atoms if there is a double bond only in position 2 and the main chain has 9-12 carbon atoms if there is a double bond only in position 4. This cholecystokinin secretion-promoting composition can be used as an appetite suppressant. By adding this cholecystokinin secretion-promoting composition to food, appetite-suppressing food products can be provided.

Abstract: Disclosed is a safe and non-toxic prophylactic or therapeutic composition for diabetes or obesity. The prophylactic or therapeutic composition for diabetes or obesity comprises as an active ingredient, a calcium receptor activator such as ?-Glu-X-Gly, wherein X represents an amino acid or an amino acid derivative; ?-Glu-Val-Y, wherein Y represents an amino acid or an amino acid derivative; ?-Glu-Ala; ?-Glu-Gly; ?-Glu-Cys; ?-Glu-Met; ?-Glu-Thr; ?-Glu-Val; ?-Glu-Orn; Asp-Gly; Cys-Gly; Cys-Met; Glu-Cys; Gly-Cys; Leu-Asp; ?-Glu-Met(O); ?-Glu-?-Glu-Val; ?-Glu-Val-NH2; ?-Glu-Val-ol; ?-Glu-Ser; ?-Glu-Tau; ?-Glu-Cys(S-Me)(O); ?-Glu-Leu; ?-Glu-Ile; ?-Glu-t-Leu; ?-Glu-Cys(S-Me); cinacalcet; a cinacalcet analogue compound and protamine.