Abstract: A toner comprising a toner particle comprising a magnetic body, and a silica fine particle on a surface of the toner particle, wherein fragment ions corresponding to a D unit structure are observed in a specific measurement; when the silica fine particle is dispersed in a mixed solution of ethanol and aqueous solution of NaCl, followed by a titration operation using sodium hydroxide, a titer is within a specific range; in a chemical shift obtained by a specific measurement, with D as an area of a peak having a peak top present in a range from ?25 to ?15 ppm, and with D1 as an area of a peak having a peak top present in a range of more than ?19 ppm and ?17 ppm or less, D and D1 are in a specific ratio; and the magnetic body is present on the surface of the toner particle.

Abstract: A toner comprises a toner particle and silica fine particles, wherein, fragment ions of a D unit structure are observed in time-of-flight secondary ion mass spectrometry measurement of the silica fine particles, in a titration operation of the silica fine particles using NaOH, the titer is within a specific range, an area of a peak from ?25 to ?15 ppm in 29Si-NMR measurement of the silica fine particles is denoted by D, the sum of the areas of peaks from ?140 to 100 ppm is denoted by S, and an area of a peak from more than ?19 ppm to ?17 ppm or less is denoted by D1, the specific surface area of the silica fine particles, D, D1, and S satisfy specific relationships, and a specific amount of a specific polyvalent metal element is present on the surface of the toner particle.

Abstract: A toner including a polyester resin-including toner particle and a silica fine particle, wherein fragment ions corresponding to a D unit structure are observed in TOF-SIMS measurement of the silica fine particle, where the silica fine particle is dispersed in a specific mixed liquid and a titration operation using sodium hydroxide is performed, the titer is within a specific range, where an area of a peak having a peak top within the range from ?25 to ?15 ppm in 29Si-NMR measurement of the silica fine particle is denoted by D and an area of a peak having a peak top within the range from more than ?19 ppm to ?17 ppm or less is denoted by D1, the specific surface area of the silica fine particle, D and D1 satisfy specific relationships, and the polyester resin is present on the surface of the toner particle.

Abstract: A toner includes a toner particle including a release agent, and a silica fine particle on a surface of the toner particle. Fragment ions corresponding to a D unit structure are observed in a specific measurement; when the silica fine particle is dispersed in a mixed solution of ethanol and aqueous solution of NaCl, followed by a titration operation using sodium hydroxide a titer is within a specific range; in a chemical shift obtained by a specific measurement, with D as an area of a peak having a peak top present in a range from -25 to -15 ppm, and with D1 as an area of a peak having a peak top present in a range of more than -19 ppm and -17 ppm or less, D and D1 are in a specific ratio. The release agent is present on the surface of the toner particle.

Abstract: A toner includes a toner particle, and a silica fine particle on a surface of the toner particle. Fragment ions corresponding to a D unit structure are observed in a specific measurement; when the silica fine particle is dispersed in a mixed solution of ethanol and aqueous solution of NaCl, followed by a titration operation using sodium hydroxide, a titer is within a specific range; in a chemical shift obtained by a specific measurement, with D as an area of a peak having a peak top present in a range from -25 to -15 ppm, and with D1 as an area of a peak having a peak top present in a range of more than -19 ppm and -17 ppm or less, D and D1 are in a specific ratio; and a vinyl-based resin having a specific structure is present on the surface of the toner particle.

Abstract: A toner comprising a toner particle comprising a binder resin, a crystalline material, and a silica particle, wherein a number average particle diameter D1 of the silica particle comprised in the toner particle is 400 to 3000 nm; the silica particle has a pointed portion; and the crystalline material comprises a compound having an ester group.

Abstract: The toner is a toner including a toner particle comprising a binder resin, a crystalline material, wherein, when a ratio of an area occupied by the crystalline material in a toner surface observed with a scanning electron microscope after ruthenium-staining the toner under a specific condition (1) is represented by S1 (%), a ratio of an area occupied by the crystalline material in the toner surface observed with the scanning electron microscope after ruthenium-staining the toner under a condition (2) is represented by S2 (%), and a dispersion diameter of a plurality of domains formed of the crystalline material on the toner surface observed with the scanning electron microscope after the ruthenium-staining the toner under the condition (2) is represented by R2 (nm), the following expressions (1), (2), and (3) are satisfied. 0 . 0 ? S 1 ? 0.5 ( 1 ) 1.0 ? S 2 ? 10.

Abstract: There is provided a toner containing: a toner particle containing a binder resin, a releasing agent, and a colorant; and an iron oxide particle present on a surface of the toner particle, in which the iron oxide particle has a surface containing a compound having a specific structure.

Abstract: Provided is a method of producing a toner including a toner particle, the method including: a granulation step of mixing a polymerizable monomer composition containing a polymerizable monomer and an aqueous medium to form a suspension of particles of the polymerizable monomer composition; and a polymerization step of polymerizing the polymerizable monomer in each of the particles of the polymerizable monomer composition in the presence of a metal phosphate containing aluminum as a metal element to provide the toner particle, the content ratio of aluminum in the metal phosphate containing aluminum being 1.0 mol % or more and 95.0 mol % or less with respect to all metal elements, the metal phosphate containing aluminum being obtained by adding an aluminum compound to the aqueous medium and/or the suspension.

Abstract: Provided is a method of producing a toner including a toner particle, the method including: a granulation step of mixing a polymerizable monomer composition containing a polymerizable monomer and an aqueous medium to form a suspension of particles of the polymerizable monomer composition; and a polymerization step of polymerizing the polymerizable monomer in each of the particles of the polymerizable monomer composition in the presence of a metal phosphate containing aluminum as a metal element to provide the toner particle, the content ratio of aluminum in the metal phosphate containing aluminum being 1.0 mol % or more and 95.0 mol % or less with respect to all metal elements, the metal phosphate containing aluminum being obtained by adding an aluminum compound to the aqueous medium and/or the suspension.

Abstract: A sample processing device for a microchip, including: a sample vessel for packing a sample therein; and a reaction vessel which is continuous with the sample vessel through a channel, and to which the sample is sequentially delivered to be packed and mixed therein, in which the sample is repeatedly delivered between the sample vessel and the reaction vessel through the channel so that the sample is stirred and mixed.

Abstract: Provided is a sample packing device for packing a sample with respect to a microchip for performing reaction of a micro component contained in the sample, the microchip at least including: a sample reservoir; a reaction reservoir; and a channel connected between the sample reservoir and the reaction reservoir, in which a package including a sample chamber packed in advance with the sample is mounted on the microchip so as to pack the sample in the sample chamber into the sample reservoir.

Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.

Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.

Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.

Abstract: Provided is a sample packing device for packing a sample with respect to a microchip for performing reaction of a micro component contained in the sample, the microchip at least including: a sample reservoir; a reaction reservoir; and a channel connected between the sample reservoir and the reaction reservoir, in which a package including a sample chamber packed in advance with the sample is mounted on the microchip so as to pack the sample in the sample chamber into the sample reservoir.

Abstract: Provided is a sample packing device for packing a sample with respect to a microchip for performing reaction of a micro component contained in the sample, the microchip at least including: a sample reservoir; a reaction reservoir; and a channel connected between the sample reservoir and the reaction reservoir, in which a package including a sample chamber packed in advance with the sample is mounted on the microchip so as to pack the sample in the sample chamber into the sample reservoir.

Abstract: For heating or cooling a sample contained in a vessel portion through a heat transfer member held in contact with the vessel portion, there is used the vessel portion, which has a part formed of an elastic member, expands and contracts for injection and discharge of the sample, is closed other than a connecting port with a channel connected to the vessel, and expands and contracts for injection and discharge of the sample. The vessel portion expands correspondingly to the injection when the sample is injected through an inflow path serving as the channel into the vessel portion contracting in a non-contacting state with the heat transfer member. A predetermined amount of sample is injected into the vessel portion so as to expand the vessel portion, and the vessel portion comes into contact with the heat transfer member. The vessel portion is heated or cooled through the heat transfer member.

Abstract: For heating or cooling a sample contained in a vessel portion through a heat transfer member held in contact with the vessel portion, there is used the vessel portion, which has a part formed of an elastic member, expands and contracts for injection and discharge of the sample, is closed other than a connecting port with a channel connected to the vessel, and expands and contracts for injection and discharge of the sample. The vessel portion expands correspondingly to the injection when the sample is injected through an inflow path serving as the channel into the vessel portion contracting in a non-contacting state with the heat transfer member. A predetermined amount of sample is injected into the vessel portion so as to expand the vessel portion, and the vessel portion comes into contact with the heat transfer member. The vessel portion is heated or cooled through the heat transfer member.

Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.