Patents by Inventor Tohru Iino

Tohru Iino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9957496
    Abstract: Provided are a method for regulating acid resistance of a microorganism by suppressing the expression of the fadD gene therein and a screening method for a microorganism having acid resistance by using the expression level of the fadD gene as an index. A method for regulating acid resistance of a microorganism, including suppressing the expression of fadD gene present in the microorganism.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: May 1, 2018
    Assignee: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Hoshitaka Matsumoto, Mika Miura, Mayumi Kiwaki, Tohru Iino
  • Patent number: 9788557
    Abstract: Disclosed is a novel lactic acid bacterium belonging to Lactobacillus plantarum, which has an excellent fermentative ability affording high achievable cell counts even if various vegetable or fruit juices are used as fermentative substrates. The lactic acid bacterium belonging to Lactobacillus plantarum is characterized by the achievable viable cell counts being 108 CFU/ml or more in both cases when 100% juice of grape or of orange is used as fermentative substrate.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: October 17, 2017
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Tohru Iino, Norie Masuoka, Fumiyasu Ishikawa, Koichi Yoshimura, Eiji Hayashida
  • Publication number: 20170022491
    Abstract: Provided are a method for regulating acid resistance of a microorganism by suppressing the expression of the fadD gene therein and a screening method for a microorganism having acid resistance by using the expression level of the fadD gene as an index. A method for regulating acid resistance of a microorganism, including suppressing the expression of fadD gene present in the microorganism.
    Type: Application
    Filed: December 3, 2014
    Publication date: January 26, 2017
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Hoshitaka MATSUMOTO, Mika MIURA, Mayumi KIWAKI, Tohru IINO
  • Patent number: 9139837
    Abstract: Provided is a gene that is useful for imparting hydrogen peroxide resistance to a microorganism. Also provided is a method for using the same. The hydrogen peroxide resistance-imparting gene encoding a protein selected from the following proteins (a) to (c): (a) a protein having the amino acid sequence of SEQ ID NO: 2; (b) a protein which has an amino acid sequence equivalent to the amino acid sequence of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits hydrogen peroxide resistance-imparting activity; and (c) a protein which has an amino acid sequence having an identity of 85% or higher to the amino acid sequence of (a), and which exhibits hydrogen peroxide resistance-imparting activity.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: September 22, 2015
    Assignee: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Masaki Serata, Mayumi Kiwaki, Tohru Iino
  • Publication number: 20140141437
    Abstract: Provided is a gene that is useful for imparting hydrogen peroxide resistance to a microorganism. Also provided is a method for using the same. The hydrogen peroxide resistance-imparting gene encoding a protein selected from the following proteins (a) to (c): (a) a protein having the amino acid sequence of SEQ ID NO: 2; (b) a protein which has an amino acid sequence equivalent to the amino acid sequence of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits hydrogen peroxide resistance-imparting activity; and (c) a protein which has an amino acid sequence having an identity of 85% or higher to the amino acid sequence of (a), and which exhibits hydrogen peroxide resistance-imparting activity.
    Type: Application
    Filed: March 2, 2012
    Publication date: May 22, 2014
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Masaki Serata, Mayumi Kiwaki, Tohru Iino
  • Publication number: 20130064928
    Abstract: Disclosed is a novel lactic acid bacterium belonging to Lactobacillus plantarum, which has an excellent fermentative ability affording high achievable cell counts even if various vegetable or fruit juices are used as fermentative substrates. The lactic acid bacterium belonging to Lactobacillus plantarum is characterized by the achievable viable cell counts being 108 CFU/ml or more in both cases when 100% juice of grape or of orange is used as fermentative substrate.
    Type: Application
    Filed: March 15, 2011
    Publication date: March 14, 2013
    Applicant: Kabushiki Kaisha Yakult Honsha
    Inventors: Tohru Iino, Norie Masuoka, Fumiyasu Ishikawa, Koichi Yoshimura, Eiji Hayashida
  • Patent number: 7993903
    Abstract: To provide a bacterium belonging to the genus Bifidobacterium which is excellent in a survival ability in the gastrointestinal tract, has an effect of inhibiting the cholesterol absorption in the intestinal tract, and is excellent in lipid metabolism ameliorating effects including decreasing the blood cholesterol level and the like, and shows a high survival rate after storage, and a cholesterol absorption inhibitor using the same. The invention provides a cholesterol absorption inhibitor containing, as an active ingredient, at least one microorganism selected from Bifidobacterium animalis subsp. animalis YIT 10394, Bifidobacterium animalis subsp. lactis JCM 1253, Bifidobacterium animalis subsp. lactis JCM 7117, and Bifidobacterium pseudolongum subsp. globosum.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: August 9, 2011
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Hiroko Hayakawa, Tohru Iino, Fumiyasu Ishikawa
  • Publication number: 20090170185
    Abstract: To provide a bacterium belonging to the genus Bifidobacterium which is excellent in a survival ability in the gastrointestinal tract, has an effect of inhibiting the cholesterol absorption in the intestinal tract, and is excellent in lipid metabolism ameliorating effects including decreasing the blood cholesterol level and the like, and shows a high survival rate after storage, and a cholesterol absorption inhibitor using the same. The invention provides a cholesterol absorption inhibitor containing, as an active ingredient, at least one microorganism selected from Bifidobacterium animalis subsp. animalis YIT 10394, Bifidobacterium animalis subsp. lactis JCM 1253, Bifidobacterium animalis subsp. lactis JCM 7117, and Bifidobacterium pseudolongum subsp. globosum.
    Type: Application
    Filed: September 7, 2006
    Publication date: July 2, 2009
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Hiroko Hayakawa, Tohru Iino, Fumiyasu Ishikawa