Abstract: A method and apparatus are disclosed for quickly and exactly locating a desired structure in a specimen or the like located on a plate or slide, and then preparing an accurate, embedded specimen block for later use, and particularly for preparing thin sections, e.g., 0.1 microns or less, on a microtome machine, for microscopic examination.

Abstract: An improved capsule and clamping apparatus and a method of using the same are disclosed. The capsule has a filling end and specimen end with a preformed opening at its filling end. The capsule has portions on the filling end for holding the capsule in a perpendicular position on a slide or the like so that the capsule may be clamped perpendicular in sealed relationship with the slide. Embedding material can then be poured into the filling end of the capsule for quickly preparing an accurate, embedded specimen block for later use, such as preparing sections, and particularly thick sections (1 to 6 microns) on a microtome machine, for microscopic examination.