Patents by Inventor Tohru Kino

Tohru Kino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Publication number: 20050124646
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Application
    Filed: November 9, 2004
    Publication date: June 9, 2005
    Applicant: FUJISAWA PHARMACEUTICAL CO., LTD.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Publication number: 20040029908
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplanation, graft-versus-host diseases by medulla ossium transplanation, autoimmune diseases, infectious diseases, and the like, which can be represented by the formula: 1
    Type: Application
    Filed: May 1, 2003
    Publication date: February 12, 2004
    Applicant: FUJISAWA PHARMACEUTICAL CO., LTD.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and pharmaceutical composition containing the same
    Publication number: 20030229115
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: 1
    Type: Application
    Filed: April 25, 2003
    Publication date: December 11, 2003
    Applicant: FUJISAWA PHARMACEUTICAL CO., LTD.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Publication number: 20030170831
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: 1
    Type: Application
    Filed: September 20, 2002
    Publication date: September 11, 2003
    Applicant: Fujisawa Pharmaceutical Co. Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Method for inhibiting interleukin-2 production using tricyclo compounds
    Patent number: 6482845
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: November 19, 2002
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Method for inhibiting lymphokine production
    Patent number: 6201005
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: March 13, 2001
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Method of immunosuppression
    Patent number: 6028097
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: February 22, 2000
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Process for production of tricyclo compounds with streptomyces
    Patent number: 5830717
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: December 3, 1996
    Date of Patent: November 3, 1998
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Strain of Streptomyces for the production of tricyclo compounds
    Patent number: 5624842
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: April 29, 1997
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 5565559
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: October 15, 1996
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 5496727
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: March 5, 1996
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Process for producing WS-9326A and WS-9326B
    Patent number: 5436140
    Abstract: The novel peptides WS-9326A, WS-9326B, their derivatives and pharmaceutically acceptable salts thereof have useful pharmacological activities, particularly in the treatment and/or prevention of asthma and/or pain. A method for the production of the peptides WS-9326A and WS-9326B and derivatives thereof using Streptomyces violaceoniger No. 9326 in a biologically pure form is described herein.
    Type: Grant
    Filed: April 11, 1994
    Date of Patent: July 25, 1995
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Tohru Kino, Motoaki Nishikawa, Masami Ezaki, Sumio Kiyoto, Masakuni Okuhara, Shigehiro Takase, Satoshi Okada, Nobuharu Shigematsu
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 5266692
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: June 18, 1992
    Date of Patent: November 30, 1993
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 5254562
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: June 18, 1992
    Date of Patent: October 19, 1993
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Peptides WS-9326a and WS-9326b, derivatives thereof and uses thereof
    Patent number: 5217952
    Abstract: This invention relates to the novel peptides WS-9326A, WS-9326B, their derivatives and pharmaceutically acceptable salts thereof which have pharmacological activities, particularly in the treatment and/or prevention of asthma and/or pain.
    Type: Grant
    Filed: November 20, 1991
    Date of Patent: June 8, 1993
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Tohru Kino, Motoaki Nishikawa, Masami Ezaki, Sumio Kiyoto, Masakuni Okuhara, Shigehiro Takase, Satoshi Okada, Nobuharu Shigematsu
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 5110811
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: March 9, 1990
    Date of Patent: May 5, 1992
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 4956352
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: August 17, 1989
    Date of Patent: September 11, 1990
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Method for immunosuppression
    Patent number: 4929611
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: May 30, 1986
    Date of Patent: May 29, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka
  • Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
    Patent number: 4894366
    Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
    Type: Grant
    Filed: November 20, 1985
    Date of Patent: January 16, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka