Patents by Inventor Tohru Yoshimura

Tohru Yoshimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210043739
    Abstract: Provided is a semiconductor device comprising a semiconductor substrate, wherein the semiconductor substrate includes a hydrogen containing region including hydrogen, and the hydrogen containing region includes a high concentration region with a higher carrier concentration than a virtual carrier concentration determined based on a concentration of hydrogen included and an activation ratio of hydrogen. The semiconductor substrate includes an N type drift region, an N type emitter region that has a higher carrier concentration than that in the drift region, a P type base region, a P type collector region provided to be in contact with a lower surface of the semiconductor substrate, and an N type buffer region that is provided between the collector region and the drift region, and has a higher carrier concentration than that in the drift region, and the hydrogen containing region is included in the buffer region.
    Type: Application
    Filed: October 22, 2020
    Publication date: February 11, 2021
    Inventors: Yoshiharu KATO, Toru AJIKI, Tohru SHIRAKAWA, Misaki TAKAHASHI, Kaname MITSUZUKA, Takashi YOSHIMURA, Yuichi ONOZAWA, Hiroshi TAKISHITA, Soichi YOSHIDA
  • Publication number: 20190359712
    Abstract: The present invention provides a novel antibody binding to human CD3, and a molecule having antigen binding activity that includes the antibody. The present invention provides a novel antibody binding to human CD3, a molecule having antigen binding activity that includes the antibody, and a pharmaceutical composition having cytotoxic activity that includes the antibody or the molecule as an active ingredient.
    Type: Application
    Filed: December 21, 2017
    Publication date: November 28, 2019
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Tohru TAKAHASHi, Chigusa YOSHIMURA, Shiho KOZUMA, Kensuke NAKAMURA, Chikako SUZUKI, Junya ICHIKAWA
  • Publication number: 20190257264
    Abstract: A fuel injection device including a valve body having an injection hole-formed part having a plurality of injection holes on the leading end side of the valve body. An injection hole comprises a crossing angle, ?1, between a central axis of the injection hole-formed part and an injection hole axis, and another injection hole comprises a crossing angle, ?2, between the central axis and another injection hole axis. ?2 is larger than ?1. The injection holes are formed such that a distance between the central axis and an inlet surface center of the injection hole is longer than a distance between the central axis and another inlet surface center of the another injection hole. A straight line beyond an outlet surface in the injection hole axis does not intersect with another straight line beyond another outlet surface in the another injection hole axis.
    Type: Application
    Filed: November 21, 2017
    Publication date: August 22, 2019
    Applicant: HITACHI AUTOMOTIVE SYSTEMS, LTD.
    Inventors: Akira IIZUKA, Tohru ISHIKAWA, Takao MIYAKE, Kazuki YOSHIMURA
  • Patent number: 8367368
    Abstract: A novel D-serine quantification method that can overcome various disadvantages of a conventional D-serine quantification method; a novel enzyme that can be used in the D-serine quantification method; a gene encoding the enzyme; and the like. Specifically, a novel D-serine dehydratase including (a) a protein having an amino acid sequence set forth in SEQ ID NO: 1 or (b) a protein having an amino acid sequence homologous to the amino acid sequence set forth in SEQ ID NO: 1 and having a D-serine dehydratase activity; and a D-serine quantification method including the steps of reacting a sample with the enzyme, quantifying ammonia or pyruvic acid produced by the reaction, and calculating the amount of D-serine in the sample based on a value produced by the quantification.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: February 5, 2013
    Assignee: National University Corporation Nagoya University
    Inventors: Tohru Yoshimura, Tomokazu Ito
  • Publication number: 20120244520
    Abstract: A novel D-serine quantification method that can overcome various disadvantages of a conventional D-serine quantification method; a novel enzyme that can be used in the D-serine quantification method; a gene encoding the enzyme; and the like. Specifically, a novel D-serine dehydratase including (a) a protein having an amino acid sequence set forth in SEQ ID NO: 1 or (b) a protein having an amino acid sequence homologous to the amino acid sequence set forth in SEQ ID NO: 1 and having a D-serine dehydratase activity; and a D-serine quantification method including the steps of reacting a sample with the enzyme, quantifying ammonia or pyruvic acid produced by the reaction, and calculating the amount of D-serine in the sample based on a value produced by the quantification.
    Type: Application
    Filed: March 26, 2012
    Publication date: September 27, 2012
    Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Tohru Yoshimura, Tomokazu Ito
  • Publication number: 20100190196
    Abstract: A novel D-serine quantification method that can overcome various disadvantages of a conventional D-serine quantification method; a novel enzyme that can be used in the D-serine quantification method; a gene encoding the enzyme; and the like. Specifically, a novel D-serine dehydratase including (a) a protein having an amino acid sequence set forth in SEQ ID NO: 1 or (b) a protein having an amino acid sequence homologous to the amino acid sequence set forth in SEQ ID NO: 1 and having a D-serine dehydratase activity; and a D-serine quantification method including the steps of reacting a sample with the enzyme, quantifying ammonia or pyruvic acid produced by the reaction, and calculating the amount of D-serine in the sample based on a value produced by the quantification.
    Type: Application
    Filed: October 16, 2007
    Publication date: July 29, 2010
    Applicant: National University Corporation Nagoya University
    Inventors: Tohru Yoshimura, Tomokazu Ito
  • Patent number: 7135306
    Abstract: A method for detecting or measuring homocysteine in a sample includes the steps of (a) reacting a D-amino acid present in a sample with a D-amino acid converting enzyme to convert the D-amino acid into a substance that does not serve as a substrate of D-amino acid oxidase or D-amino acid acetyltransferase; (b) reducing homocysteine in the sample with a thiol compound; (c) reacting the reduced homocysteine with a methyltransferase and a methyl donor to newly produce D-amino acid; and (d) reacting the produced D-amino acid with the D-amino acid oxidase or the D-amino acid acetyltransferase in the presence of an SH reagent to produce hydrogen peroxide, and color-developing the produced hydrogen peroxide by using an oxidative color-developing agent.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: November 14, 2006
    Assignee: Alfresa Pharma Corproation
    Inventors: Nobuyoshi Esaki, Tohru Yoshimura, Naoto Matsuyama, Koji Mizuno, Takayuki Bogaki, Toshitaka Minetoki, Kenji Ozeki
  • Publication number: 20060166300
    Abstract: A method for detecting or measuring homocysteine in a sample includes the steps of (a) reacting a D-amino acid present in a sample with a D-amino acid converting enzyme to convert the D-amino acid into a substance that does not serve as a substrate of D-amino acid oxidase or D-amino acid acetyltransferase; (b) reducing homocysteine in the sample with a thiol compound; (c) reacting the reduced homocysteine with a methyltransferase and a methyl donor to newly produce D-amino acid; and (d) reacting the produced D-amino acid with the D-amino acid oxidase or the D-amino acid acetyltransferase in the presence of an SH reagent to produce hydrogen peroxide, and color-developing the produced hydrogen peroxide by using an oxidative color-developing agent.
    Type: Application
    Filed: January 28, 2004
    Publication date: July 27, 2006
    Applicant: ALFRESA PHARMA CORPORATION
    Inventors: Nobuyoshi Esaki, Tohru Yoshimura, Naoto Matsuyama, Koji Mizuno, Takayuki Bogaki, Toshitaka Minetoki, Kenji Ozeki
  • Publication number: 20010006823
    Abstract: A chromatography assay device and method for use with whole blood samples utilizing a red blood cell separating agent to aggregate red blood cells and permit plasma or serum to flow by capillary action and a neutralizing agent to neutralize any effects the red blood cell separating agent may have on the device and method.
    Type: Application
    Filed: January 15, 1998
    Publication date: July 5, 2001
    Inventors: TOHRU YOSHIMURA, TOSHIHIRO OGASAWARA, MICHIHIRO SAITO, JOHN P. GROFF
  • Patent number: 5023327
    Abstract: An organism which generates energy through the decomposition of cellulose such as termites can be selectively destroyed with a fluorine-containing glycoside of the formula: ##STR1## wherein n is an even number of 2 to 20, and m is an integer of 0 to 5.
    Type: Grant
    Filed: February 27, 1989
    Date of Patent: June 11, 1991
    Assignee: Daikin Industries Ltd.
    Inventors: Ryohei Yamaoka, Keizo Hayashiya, Tohru Yoshimura, Eiji Seki, Tetsuya Masutani, Katsuhiko Kitahara
  • Patent number: 4007364
    Abstract: A writing instrument internally houses a miniature electronic calculator which includes a key input section comprising a single key which is subjected to a rotational or translational movement to select one of a plurality of switches. When the key is depressed against a bias applied thereto while in a position in which it has selected one of the switches, the selected switch is controlled thereby to input an associated information into an arithmetic unit of the calculator. The instrument case or key is marked with indicia which designate the key positions for the convenience of selecting input informations. The key input section comprises an insulating substrate on which an array of a plurality of stationary contacts are formed along the direction of movement of the key, a flexible insulating film disposed in opposing relationship with the stationary contacts, and a movable contact deposited on the side of film which faces the stationary contacts so as to extend in the direction of movement of the key.
    Type: Grant
    Filed: April 28, 1975
    Date of Patent: February 8, 1977
    Assignee: Hoshidenki-Seizo Kabushiki Kaisha
    Inventors: Shin Ojima, Kazuhiko Ohgami, Kazutaka Watanabe, Tohru Yoshimura, Masaya Katou, Nozomu Matsuoka