Abstract: Described is a medical device lead including a lead body having a conductor lumen including an inner surface. The lead also includes a conductor assembly extending through the conductor lumen; the conductor assembly comprising a conductor member and an outer insulative layer; and an electrode coupled to the conductor cable. The outer insulative layer includes a textured external surface that reduces the coefficient of friction between the outer insulative layer and the inner surface of the conductor lumen through which the conductor assembly extends. Methods of forming the conductor assembly are also described.

Abstract: The inventions disclosed herein relate to systems for securing medical devices to a blood vessel of a patient, including securing a vessel deforming component to a blood vessel. Certain embodiments relate to wraps configured to be secured around a blood vessel, including wraps configured to hold a vessel deformer adjacent a blood vessel, and further including, for example, a pulsatile balloon adjacent the aorta.

Abstract: Systems, methods, and devices for treating pulmonary arterial hypertension are provided. The system comprises an implantable actuator that compresses the pulmonary artery.

Abstract: Described is a medical device lead including a lead body having a conductor lumen including an inner surface. The lead also includes a conductor assembly extending through the conductor lumen; the conductor assembly comprising a conductor member and an outer insulative layer; and an electrode coupled to the conductor cable. The outer insulative layer includes a textured external surface that reduces the coefficient of friction between the outer insulative layer and the inner surface of the conductor lumen through which the conductor assembly extends. Methods of forming the conductor assembly are also described.

Abstract: Described is a medical device lead including a lead body having a conductor lumen including an inner surface. The lead also includes a conductor assembly extending through the conductor lumen; the conductor assembly comprising a conductor member and an outer insulative layer; and an electrode coupled to the conductor cable. The outer insulative layer includes a textured external surface that reduces the coefficient of friction between the outer insulative layer and the inner surface of the conductor lumen through which the conductor assembly extends. Methods of forming the conductor assembly are also described.

Abstract: The inventions disclosed herein relate to systems for securing medical devices to a blood vessel of a patient, including securing a vessel deforming component to a blood vessel. Certain embodiments relate to wraps configured to be secured around a blood vessel, including wraps configured to hold a vessel deformer adjacent a blood vessel, and further including, for example, a pulsatile balloon adjacent the aorta.

Abstract: A solventless method for forming a coating on a medical electrical lead is described. The method includes combining particles of a therapeutic agent with a polymeric material in a flowable form in the absence of a solvent to form a uniform suspension. A predetermined amount of the suspension is dispensed onto a portion of the lead and is then cured to form the therapeutic agent eluting layer. Additional layers such as a primer layer, fluoro-opaque layer and/or a topcoat layer can be formed using the solventless method. Employing a solventless method may avoid contraction of the layer being formed due to solvent evaporation during the curing process, and may facilitate greater control over the thickness of the therapeutic agent eluting coating.

Abstract: The various embodiments disclosed herein relate to percutaneous interface lines and related methods for implanting such lines. Each percutaneous interface line has an internal component coupleable to a percutaneous component with an internal connector. The percutaneous component can have a Y-shaped end having two arms, one arm having a lumen and another arm having at least one wire. The methods for implanting a percutaneous interface line include the use of a tunneling tool having a flexible rod and a replaceable dilator tip.

Abstract: Described is a medical device lead including a lead body having a conductor lumen including an inner surface. The lead also includes a conductor assembly extending through the conductor lumen; the conductor assembly comprising a conductor member and an outer insulative layer; and an electrode coupled to the conductor cable. The outer insulative layer includes a textured external surface that reduces the coefficient of friction between the outer insulative layer and the inner surface of the conductor lumen through which the conductor assembly extends. Methods of forming the conductor assembly are also described.

Abstract: A solventless method for forming a coating on a medical electrical lead is described. The method includes combining particles of a therapeutic agent with a polymeric material in a flowable form in the absence of a solvent to form a uniform suspension. A predetermined amount of the suspension is dispensed onto a portion of the lead and is then cured to form the therapeutic agent eluting layer. Additional layers such as a primer layer, fluoro-opaque layer and/or a topcoat layer can be formed using the solventless method. Employing a solventless method may avoid contraction of the layer being formed due to solvent evaporation during the curing process, and may facilitate greater control over the thickness of the therapeutic agent eluting coating.